Home > Name List By b > Benzeneacetamide, a-[2-(dimethylamino)propyl]-a-phenyl-

CAS No 60-46-8 , Benzeneacetamide, a-[2-(dimethylamino)propyl]-a-phenyl-

  • Name: Benzeneacetamide, a-[2-(dimethylamino)propyl]-a-phenyl-
  • Synonyms: BL 139; Dimevamide; Aminopentamide;Centrine; dl-Aminopentamide;Benzeneacetamide, a-[2-(dimethylamino)propyl]-a-phenyl-; a,a-Diphenyl-g-dimethylaminovaleramide; Valeramide-OM;Valeramide,4-(dimethylamino)-2,2-diphenyl- (6CI,7CI,8CI);
  • CAS Registry Number:
  • Flash Point: 236.6°C
  • Boiling Point: 467.7°C at 760 mmHg
  • Density: 1.069g/cm3
  • Refractive index: 1.564
  • Safety Statements: Poison by intraperitoneal and intravenous routes. Moderately toxic by ingestion. An anticholinergic. Used in veterinary medicine as an anticonvulsant and anti-emetic. When heated to decomposition it emits toxic fumes of NOx.
  • Flash Point: 236.6°C
  • EINECS: 200-479-8
  • Molecular Weight: 296.40666
  • InChI: InChI=1/C19H24N2O/c1-15(21(2)3)14-19(18(20)22,16-10-6-4-7-11-16)17-12-8-5-9-13-17/h4-13,15H,14H2,1-3H3,(H2,20,22)
  • Molecular Formula: C19H24N2O
  • Molecular Structure:CAS No:60-46-8 Benzeneacetamide, a-[2-(dimethylamino)propyl]-a-phenyl-

Related products

Search by region :

Select to

60-46-8 Aminopentamid Sulfate

  • Aminopentamid Sulfate CAS: 60-46-8 Spc.: USP 95 - 103.0 % Guangzhou Topwork Chemical Co.,Ltd. also has the capability in producing Chinese gallnut raw materials, which are widely used in medical, chemical, food, printing & dyeing, astronavigation and...
  • Min. Order: 11111
  • FOB Price: USD1 - 11 /
  • China Guangzhou Topwork Chemical Co., Ltd. [Manufacturer]
  • Tel: 86-20-87317062
  • Address: A04,Keyuan Business Centre, No.81, BULIDING32, Xianliezhong Road, Guangzhou,GuangdongChina
Contact Supplier

60-46-8 Aminopentamid Sulfate

  • FOB Price: USD8000 - 9000 /
  • China Chemland Internaitional Co,LTD [Trading Company, Buying Office, Other]
  • Tel: 852-0-13728751448
  • Fax: --
  • Address: Kowloon hongkong,HongkongChina
Contact Supplier

60-46-8 Dimevamide

  • Dimevamide, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
Contact Supplier

60-46-8 Dimevamide

  • Dimevamide, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,nullChina
Contact Supplier

60-46-8 Benzeneacetamide, a-[2-(dimethylamino)propyl]-a-phenyl-

Contact Supplier

60-46-8 DIMEVAMIDE

  • Canada Dalton Pharma Services [Manufacturer]
  • Tel: (416)-661-2102/ (800)-567-5060 (Canada Only)
  • Fax: 416-661-2108
  • Address: Dalton Pharma Services
    349 Wildcat Rd.
    Toronto, ON
    M3J 2S3
    CANADA null,nullCanada
Contact Supplier

60-46-8 METOCLORAMIDE

  • China NINGBO PANGS CHEM INT'L CO.,LTD [Manufacturer]
  • Tel: +86-574-27666821
  • Fax: +86-574-27668686 / 27668810
  • Address: FLOOR 21,BUILDING 11,
    XINTIANDI,NO.689,
    SHIJIROAD,
    NINGBO,CHINA 315040 null,nullChina
Contact Supplier

60-46-8 DIMEVAMIDE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
Contact Supplier

Select to

1/1
References of Benzeneacetamide, a-[2-(dimethylamino)propyl]-a-phenyl-
Title: Aminopentamide
CAS Registry Number: 60-46-8
CAS Name: a-[2-(Dimethylamino)propyl]-a-phenylbenzeneacetamide
Synonyms: 4-dimethylamino-2,2-diphenylvaleramide; a,a-diphenyl-g-dimethylaminovaleramide; dimevamide
Manufacturers' Codes: BL-139
Molecular Formula: C19H24N2O
Molecular Weight: 296.41
Percent Composition: C 76.99%, H 8.16%, N 9.45%, O 5.40%
Literature References: Anticholinergic. Prepn similar to that of methadone, starts by condensing diphenylmethyl cyanide with chlorodimethylaminopropane: Walton, et al., J. Chem. Soc. 1949, 648; Cheney et al., J. Org. Chem. 17, 770 (1952); Specter, US 2647926 (1953 to Bristol). Prepn of optical isomers: Wheatley et al., J. Org. Chem. 19, 794 (1954). See also Moffett, Aspergren, J. Am. Chem. Soc. 79, 4451 (1957). Toxicity study: Cazort, J. Pharmacol. Exp. Ther. 100, 325 (1950).
 
Derivative Type: dl-Form
Properties: Long prisms from dilute alcohol, mp 183-184°. Practically insol in water.
Melting point: mp 183-184°
 
Derivative Type: d-Form
Properties: Crystals from petr ether, mp 136.5-137.5° (sintering). [a]D23 +98.9° (methanol).
Melting point: mp 136.5-137.5° (sintering)
Optical Rotation: [a]D23 +98.9° (methanol)
 
Derivative Type: l-Form
Properties: Crystals from petr ether, mp 136.5-137.5° (sintering). [a]D23 -101.9° (methanol).
Melting point: mp 136.5-137.5° (sintering)
Optical Rotation: [a]D23 -101.9° (methanol)
 
Derivative Type: dl-Form hydrochloride
Molecular Formula: C19H24N2O.HCl
Molecular Weight: 332.87
Percent Composition: C 68.56%, H 7.57%, N 8.42%, O 4.81%, Cl 10.65%
Properties: Slightly deliquescent leaflets from alcohol + ether, dec 190-191°. Bitter taste. Soluble in water, alcohol. A 1% aq soln has a pH of 6.8. LD50 in mice (mg/kg): 34.7 i.v.; 396 orally (Cazort).
Toxicity data: LD50 in mice (mg/kg): 34.7 i.v.; 396 orally (Cazort)
 
Derivative Type: dl-Form acid sulfate
Trademarks: Centrine (Fort Dodge)
Molecular Formula: C19H24N2O.H2SO4
Molecular Weight: 394.49
Percent Composition: C 57.85%, H 6.64%, N 7.10%, O 20.28%, S 8.13%
Properties: Deliquescent crystals from isopropanol + ethyl acetate, mp 185-187°. The commercial medicinal grade, mp 178-181°. Bitter taste. uv max (1% H2SO4): 258.5 nm (A1%1cm 10.3); min: 249 nm. Freely sol in water, alc. Very slightly sol in chloroform. Practically insol in ether. pH of 2.5% aq soln 1.3-2.2.
Melting point: mp 185-187°; mp 178-181°
Absorption maximum: uv max (1% H2SO4): 258.5 nm (A1%1cm 10.3)
 
Therap-Cat: Antispasmodic.
Therap-Cat-Vet: Antispasmodic; antiemetic.
Keywords: Antimuscarinic; Antispasmodic.