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CAS No 599-04-2 , (3R)-3-hydroxy-4,4-dimethyloxolan-2-one

  • Name: (3R)-3-hydroxy-4,4-dimethyloxolan-2-one
  • Synonyms: 599-04-2;(3R)-3-hydroxy-4,4-dimethyloxolan-2-one; (R)-pantolactone; (R)-Pantoyl lactone; Pantoic acid gamma-lactone; D-(-)-Pantoyl Lactone; SBB017517; pantoyl lactone;D-(-)-Pantolactone;
  • CAS Registry Number:
  • Melting Point: 91 °C(lit.)
  • Flash Point: 99°C
  • Boiling Point: 120-122 ºC
  • Density: 1.165g/cm3
  • Refractive index: -50.8 ° (C=2, H2O)
  • Safety Statements: S22;S24/25
  • Flash Point: 99°C
  • EINECS: 209-963-3
  • Molecular Weight: 130.1418
  • InchiKey: SERHXTVXHNVDKA-BYPYZUCNSA-N
  • InChI: InChI=1S/C6H10O3/c1-6(2)3-9-5(8)4(6)7/h4,7H,3H2,1-2H3/t4-/m0/s1
  • Risk Statements: S22;S24/25
  • Molecular Formula: C6H10O3
  • Molecular Structure:CAS No:599-04-2 (3R)-3-hydroxy-4,4-dimethyloxolan-2-one
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599-04-2 D-(-)-PANTOLACTONE; 99%

  • Germany ABCR GmbH & Co KG [Manufacturer]
  • Tel: +49 721 95061-0
  • Fax: +49 721 95061-80
  • Address: Im Schlehert 10
    76187 Karlsruhe
    Germany null,nullGermany
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599-04-2 D-(-)-PANTOYL LACTONE 98+%

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong null,nullHong kong
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599-04-2 D-(-)-Pantolactone

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi null,ShanXiChina
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599-04-2 D-Pantolactone

  • China Trust&We Co., Ltd. [Manufacturer]
  • Tel: +86-21-61044582
  • Fax: +86-21-61044583
  • Address: 1-102,No.11,Dongjiaominxiang Alley,
    Dongcheng District,
    Beijing 100005,China null,nullChina
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599-04-2 D-Pantolactone

  • China Shanghai Xunxin Chemical Co., Ltd [Manufacturers]
  • Tel: +86-(21)-38218795
  • Fax: +86-(21)-38218795
  • Address: 580 Lane, Kanghong Road, Pudong New District, Shanghai 201315, Shanghai,ShanghaiChina
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599-04-2 D-Pantolactone

  • China Watson International Ltd. null
  • Tel: +86-(512)-55117610
  • Fax: +86-(512)-55117630
  • Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332, null,nullChina
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599-04-2 D-(-)-PANTOYLLACTONE

  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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599-04-2 PANTOLACTONE-D

  • United States Richman Chemical, Inc. [Manufacturer]
  • Tel: 215-628-2946
  • Fax: 215-628-4262
  • Address: Richman Chemical, Inc.
    768 North Bethlehem Pike
    Lower Gwynedd, PA 19002 null,nullUnited States
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599-04-2 D-Pantolactone

  • United States Richman Chemical Inc. [Importer/Exporter]
  • Tel: +1-(215)-628-2946
  • Fax: +1-(215)-628-4262
  • Address: 768, North Bethlehem Pike, Lower Gwynedd, Pennsylvania 19002, Lower Gwynedd,PAUnited States
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599-04-2 D-PANTOLACTONE

  • Germany Beckmann-Kenko GmbH [Manufacturer]
  • Tel: +49 4241 9308-88
  • Fax: +49 4241 9308-89
  • Address: Beckmann-Kenko GmbH
    AUF DEM SCHEUNENBRINK 8
    D-27211 BASSUM, GERMANY null,nullGermany
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References of (3R)-3-hydroxy-4,4-dimethyloxolan-2-one
Title: Pantolactone
CAS Registry Number: 599-04-2
CAS Name: Dihydro-3-hydroxy-4H-dimethyl-2(3H)-furanone
Synonyms: pantoic acid g-lactone; pantoyl lactone; pantoic lactone; 2,4-dihydroxy-3,3-dimethylbutyric acid g-lactone; a-hydroxy-b,b-dimethyl-g-butyrolactone
Molecular Formula: C6H10O3
Molecular Weight: 130.14
Percent Composition: C 55.37%, H 7.75%, O 36.88%
Literature References: A degradation product of pantothenic acid from liver: Williams, Major, Science 91, 246 (1940). Important intermediate in the synthesis of pantothenic acid. May be prepd by condensing isobutyraldehyde with formaldehyde yielding a,a-dimethyl-b-hydroxypropionaldehyde which is condensed with hydrocyanic acid in the presence of calcium chloride to form racemic pantolactone. Various modifications of this procedure exist: Glaser, Monatsh. Chem. 25, 46 (1904); Stiller et al., J. Am. Chem. Soc. 62, 1785 (1940); Reichstein, Grüssner, Helv. Chim. Acta 23, 650 (1940); Carter, Ney, J. Am. Chem. Soc. 63, 312 (1941). Vast patent literature, e.g., Beckmann et al.; Klein, US 2967869 and US 3024250 (1961, 1962, both to Nopco).
 
Derivative Type: D(-)-Form
Properties: Hygroscopic crystals from benzene + petr ether, mp 92°. [a]D25 -50.7° (c = 2.05 in H2O). Can be purified by microsublimation.
Melting point: mp 92°
Optical Rotation: [a]D25 -50.7° (c = 2.05 in H2O)
 
Derivative Type: L(+)-Form
Properties: Hygroscopic crystals from benzene, mp 91°. [a]D25 +50.1° (c = 2 in H2O).
Melting point: mp 91°
Optical Rotation: [a]D25 +50.1° (c = 2 in H2O)
 
Derivative Type: DL-Form
Properties: Hygroscopic rosettes or prisms, mp 80°, bp18 130°. Freely sol in water. Sol in ether, benzene, chloroform, alcohol, carbon disulfide.
Melting point: mp 80°
Boiling point: bp18 130°