Home > Name List By other > (2R,3Z, 5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2- carboxylic acid

CAS No 58001-44-8 , (2R,3Z,
5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-
carboxylic acid

  • Name: (2R,3Z,
    5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-
    carboxylic acid
  • Synonyms: Acide clavulanique; Acido clavulanico;(2R,3Z,
    5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-
    carboxylic acid;Clavulanate; MM 14151; Antibiotic MM 14151; acidum clavulanicum; Sodium Clavulanate;
  • CAS Registry Number:
  • Transport: 25kgs
  • Density: 1.65 g/cm3
  • Refractive index: 1.644
  • Hazard Symbols: UN NO.
  • EINECS: 261-069-2
  • Molecular Weight: 199.16076
  • InchiKey: HZZVJAQRINQKSD-PBFISZAISA-N
  • InChI: InChI=1S/C8H9NO5/c10-2-1-4-7(8(12)13)9-5(11)3-6(9)14-4/h1,6-7,10H,2-3H2,
    (H,12,13)/b4-1-/t6-,7-/m1/s1
  • Molecular Formula: C8H9NO5
  • Molecular Structure:CAS No:58001-44-8 (2R,3Z,<br />5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-<br />carboxylic acid

Related products

Search by region :

Select to

58001-44-8 4-Oxa-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 3-(2-hydroxyethylidene)-7-oxo-, (2R,3Z,5R)-

Contact Supplier

58001-44-8 Clavulanic Acid

  • Clavulanic Acid, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
Contact Supplier

58001-44-8 Clavulanic acid

  • Clavulanic acid 58001-44-8 B121859
  • China bepharm ltd. null
  • Tel: 86-21-51816456
  • Address: 128 Xiangyin Road, Room C320-321 Yangpu District, Shanghai 200433, China null,nullChina
Contact Supplier

58001-44-8 CLAVULANIC ACID

  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
Contact Supplier

58001-44-8 Clavulanic Acid

  • India Manus Aktteva null
  • Tel: +91-(79)-65123395
  • Fax: +91-(79)-26463395
  • Address: 303, 3rd Floor, Royale Manor, Law Garden, Dhulia Kot Road, Ellisbridge, Ahmedabad, Gujarat 380006, null,nullIndia
Contact Supplier

58001-44-8 Clavulanic Acid, 99%

  • Clavulanic Acid, 99%
  • China Pleapharma Co.,Ltd [Manufacturer]
  • Tel: 86 23 67030808
  • Fax: 86 23 67030809
  • Address: 22F,Jingxin center,No.70 Xingguang Road,Yubei Zone,Chongqing402232 chongqingCHINA chongqing,nullChina
Contact Supplier

58001-44-8 CLAVULANIC ACID

  • China HANGZHOU THINK CHEMICAL CO. [Manufacturer]
  • Tel: +86-571-81956191/ +86-571-81956192
  • Fax: +86-571-81956190
  • Address: 425 MOGAN HILL ROAD ,
    HANGZHOU, 310011 CHINA null,nullChina
Contact Supplier

58001-44-8 Clavulanic Acid

  • India Triveni Chemicals null
  • Tel: +91-(260)-2400022, 3258683
  • Fax: +91-(260)-2400022/3264008
  • Address: 135, Pancharatna, Char Rasta, G.I.D.C., Vapi, Gujarat 396 195, null,nullIndia
Contact Supplier

58001-44-8 Clavulanic acid

  • United States CBSCHEM LIMITED null
  • Fax: (888) 557-9843
  • Address: 621 South 48th Street, Suite 115,Tempe, AZ 85281 null,nullUnited States
Contact Supplier

58001-44-8 Clavulanic Acid

  • China Qingdao Chinaoil Co., Ltd null
  • Fax: +86-532-85713888 85723888
  • Address: 22/F,Golden Light Tower,No.56, Xianggang Zhong Road, Qingdao 266071, China null,nullChina
Contact Supplier

Select to

1/2
1 2 Next
References of (2R,3Z,
5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-
carboxylic acid
Title: Clavulanic Acid
CAS Registry Number: 58001-44-8
CAS Name: [2R-(2a,3Z,5a)]-3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Manufacturers' Codes: MM 14151
Molecular Formula: C8H9NO5
Molecular Weight: 199.16
Percent Composition: C 48.25%, H 4.55%, N 7.03%, O 40.17%
Literature References: b-Lactamase inhibitor. Antibiotic produced by Streptomyces clavuligerus; first reported naturally occurring fused b-lactam containing oxygen. Isoln: M. Cole et al., DE 2517316 (1975 to Beecham), C.A. 84, 72635t (1976); A. G. Brown et al., J. Antibiot. 29, 668 (1976). Structure, x-ray crystallography: T. T. Howarth et al., Chem. Commun. 1976, 266. Total synthesis of (±)-form: P. H. Bentley et al., ibid. 1977, 748, 905; eidem, Tetrahedron Lett. 1979, 1889. b-Lactamase inhibition and antibacterial spectrum: C. Reading, M. Cole, Antimicrob. Agents Chemother. 11, 852 (1977). Mechanism of action: B. G. Spratt et al., ibid. 12, 406 (1977). Antibacterial activity, pharmacology and clinical efficacy of combination with amoxicillin: A. P. Ball et al., Lancet 1, 620 (1980); R. N. Brogden et al., Drugs 22, 337-362 (1981). In vitro and in vivo synergism with ticarcillin: R. Sutherland et al., Am. J. Med. 79, Suppl. 5B, 13 (1985).
 
Derivative Type: Combination of potassium salt with amoxicillin trihydrate
Synonyms: Co-amoxiclav
Trademarks: Amoksiklav (Lek); Augmentin (SKB); Ciblor (Inava); Clavamox (Pfizer); Clavulin (SKB); Klavocin (Pliva); Neo-Duplamox (ISF); Synulox (Pfizer)
 
Derivative Type: Combination of potassium salt with ticarcillin disodium
CAS Registry Number: 116876-37-0
Trademarks: Betabactyl (SKB); Timentin (SKB)
 
Derivative Type: Methyl ester
Molecular Formula: C9H11NO5
Molecular Weight: 213.19
Percent Composition: C 50.70%, H 5.20%, N 6.57%, O 37.52%
Properties: Oil. [a]D22 +38°.
Optical Rotation: [a]D22 +38°
 
Derivative Type: p-Nitrobenzyl ester
Molecular Formula: C15H14N2O7
Molecular Weight: 334.28
Percent Composition: C 53.90%, H 4.22%, N 8.38%, O 33.50%
Properties: Monoclinic crystals, mp 117.5-118°.
Melting point: mp 117.5-118°
 
Therap-Cat: Combination with b-lactam antibiotics as antibacterial.
Therap-Cat-Vet: Combination with b-lactam antibiotics as antibacterial.
Keywords: Antibacterial Adjuncts; ?Lactamase Inhibitors.