Title: Uridine
CAS Registry Number: 58-96-8
Synonyms: 1-b-D-Ribofuranosyluracil; uracil riboside
Molecular Formula: C9H12N2O6
Molecular Weight: 244.20
Percent Composition: C 44.27%, H 4.95%, N 11.47%, O 39.31%
Literature References: Nucleoside; widely distributed in nature. Prepd by hydrolysis of yeast nucleic acid with weak alkali,
cf. Levene, Bass,
Nucleic Acids (New York, 1931). Improved isolns: Harris, Thomas,
J. Chem. Soc. 1948, 1936; Elmore,
ibid. 1950, 2084; Lorine, Ploeser,
J. Biol. Chem. 178, 439 (1949). Crystal structure: Green
et al., Chem. Commun. 1971, 53.
Review: Basic Principles in Nucleic Acid Chemistry vol. 1, P. O. P. Ts'o, Ed. (Academic Press, New York, 1974)
passim.
Properties: Needles from dil alc, mp 165°. [a]D20 +4° (c = 2). uv max (pH 7.3): 261, 205 nm (e ′ 10-3 10.1, 9.8), Voet
et al., Biopolymers 1, 193 (1963). Sol in water. Upon prolonged refluxing with HCl, furfurol is formed.
Melting point: mp 165°
Optical Rotation: [a]D20 +4° (c = 2)
Absorption maximum: uv max (pH 7.3): 261, 205 nm (e ′ 10-3 10.1, 9.8), Voet
et al., Biopolymers 1, 193 (1963)
