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CAS No 15176-29-1 , Uridine,2'-deoxy-5-ethyl-

  • Name: Uridine,2'-deoxy-5-ethyl-
  • Synonyms: Edoxudine; RWJ 15817;Uridine,2'-deoxy-5-ethyl-;5-Ethyl-1-(2'-deoxy-b-D-ribofuranosyl)uracil;2'-Deoxy-5-ethyluridine;Aedurid; Epoxudine; b-5-Ethyldeoxyuridine; 5-Ethyldeoxyuridine; 5-Ethyl-2'-deoxyuridine; EDU; EUDR; ORF 15817; b-5-Ethyl-2'-deoxyuridine;
  • CAS Registry Number:
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: 1.389 g/cm3
  • Refractive index: 1.569
  • Safety Statements: Mutation data reported. When heated to decomposition it emits toxic vapors of NOx.
  • Flash Point: °C
  • EINECS: 239-226-1
  • Molecular Weight: 256.29
  • InChI: InChI=1/C11H16N2O5/c1-2-6-4-13(11(17)12-10(6)16)9-3-7(15)8(5-14)18-9/h4,7-9,14-15H,2-3,5H2,1H3,(H,12,16,17)/t7-,8+,9+/m0/s1
  • Molecular Formula: C11H16 N2 O5
  • Molecular Structure:CAS No:15176-29-1 Uridine,2'-deoxy-5-ethyl-
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15176-29-1 edoxudine

  • edoxudine
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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15176-29-1 Uridine,2'-deoxy-5-ethyl-

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15176-29-1 A1143 2''-DEOXY-5-ETHYL-D-URIDINE

  • United Kingdom Carbosynth Limited [Manufacturer]
  • Tel: +44 (0)1635 578444
  • Fax: +44 (0)1635 579444
  • Address: Carbosynth Limited
    8&9 Old Station Business Park
    Compton
    Berkshire
    RG20 6NE
    UK null,nullUnited Kingdom
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15176-29-1 Edoxudine

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
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15176-29-1 Edoxudine

  • Edoxudine, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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15176-29-1 Edoxudine

  • Edoxudine, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,nullChina
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15176-29-1 5-ETHYL-2''-DEOXYURIDINE

  • United States GLSynthesis Inc. [Manufacturer]
  • Tel: 508 754-6700
  • Fax: 508 754-7075
  • Address: GLSynthesis Inc.
    One Innovation Drive
    Worcester MA 01605 null,nullUnited States
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15176-29-1 EDOXUDINE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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References of Uridine,2'-deoxy-5-ethyl-
Title: Edoxudine
CAS Registry Number: 15176-29-1
CAS Name: 2¢-Deoxy-5-ethyluridine
Synonyms: 5-ethyl-2¢-deoxyuridine; 5-ethyl-3-(2¢-deoxyribosyl)uracil; EDU; EUDR
Manufacturers' Codes: ORF-15817
Trademarks: Aedurid (Robugen); Edurid (Robugen)
Molecular Formula: C11H16N2O5
Molecular Weight: 256.26
Percent Composition: C 51.56%, H 6.29%, N 10.93%, O 31.22%
Literature References: Substituted uracil with anti-herpes activity. Prepn and properties: K. K. Gauri, GB 1170565; eidem, US 3553192 (1968, 1971 both to Robugen). Synthesis via organopalladium intermediates: D. E. Bergstrom, J. L. Ruth, J. Am. Chem. Soc. 98, 1587 (1976); D. E. Bergstrom, M. K. Ogawa, ibid. 100, 8106 (1978). Physical properties: M. Swierkowski, D. Shugar, J. Med. Chem. 12, 533 (1969). Antiviral activity: E. De Clercq, D. Shugar, Biochem. Pharmacol. 24, 1073 (1975). Preferential inhibition of herpes simplex virus type 2: C.-Z. Teh, S. L. Sacks, Antimicrob. Agents Chemother. 23, 637 (1983). Synergistic effect with interferon-b, q.v., on herpes simplex virus: C. Janz, R. Wigand, Arch. Virol. 73, 135 (1982). Inhibitory effect on growth of murine leukemia cells: J. Balzarini et al., Invest. New Drugs 2, 35 (1984).
Properties: Long clear needles from acetone, mp 152-153°. uv max: 267 nm (e 9610) at pH 2, 267 nm (e 7280) at pH 1. pKa: 9.98.
Melting point: mp 152-153°
pKa: pKa: 9.98
Absorption maximum: uv max: 267 nm (e 9610) at pH 2, 267 nm (e 7280) at pH 1
Therap-Cat: Antiviral (herpes simplex).
Keywords: Antiviral; Purines/Pyrimidinones.