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CAS No 58-40-2 , N,N-dimethyl-3-phenothiazin-10-ylpropan-1-amine

  • Name: N,N-dimethyl-3-phenothiazin-10-ylpropan-1-amine
  • Synonyms: Protactyl; Ampazine;N,N-dimethyl-3-phenothiazin-10-ylpropan-1-amine; Romtiazin; Promazin; Berophen; Esparin; Sinophenin; Verophen; Promwill;
  • CAS Registry Number:
  • Flash Point: 203.4°C
  • Boiling Point: 412.7°Cat760mmHg
  • Density: 1.133g/cm3
  • Safety Statements: Human poison by unspecified route. An experimental poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of NOx and SOx.
  • Flash Point: 203.4°C
  • EINECS: 200-382-0
  • Molecular Weight: 284.4191
  • InchiKey: ZGUGWUXLJSTTMA-UHFFFAOYSA-N
  • InChI: InChI=1S/C17H20N2S/c1-18(2)12-7-13-19-14-8-3-5-10-16(14)20-17-11-6-4-9-
    15(17)19/h3-6,8-11H,7,12-13H2,1-2H3
  • Molecular Formula: C17H20N2S
  • Molecular Structure:CAS No:58-40-2 N,N-dimethyl-3-phenothiazin-10-ylpropan-1-amine

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58-40-2 10H-Phenothiazine-10-propanamine,N,N-dimethyl-

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References of N,N-dimethyl-3-phenothiazin-10-ylpropan-1-amine
Title: Promazine
CAS Registry Number: 58-40-2
CAS Name: N,N-Dimethyl-10H-phenothiazine-10-propanamine
Synonyms: 10-(3-dimethylaminopropyl)phenothiazine
Manufacturers' Codes: RP-3276; Wy-1094; A-145
Molecular Formula: C17H20N2S
Molecular Weight: 284.42
Percent Composition: C 71.79%, H 7.09%, N 9.85%, S 11.27%
Literature References: Prepd by heating a xylene soln of phenothiazine and 3-dimethylamino-1-chloropropane in the presence of sodamide: Charpentier, US 2519886 (1950 to Rh?ne-Poulenc).
Properties: Oily liq. Amine odor. Alkaline reaction. bp0.3 203-210°.
Boiling point: bp0.3 203-210°
 
Derivative Type: Hydrochloride
CAS Registry Number: 53-60-1
Trademarks: Liranol (Wyeth); Promwill (Will-Pharma); Prazine (Wyeth); Protactyl (Wyeth); Sparine (Wyeth); Talofen (Fournier)
Molecular Formula: C17H20N2S.HCl
Molecular Weight: 320.88
Percent Composition: C 63.63%, H 6.60%, N 8.73%, S 9.99%, Cl 11.05%
Properties: White to slightly yellow crystals, dec 181° (microblock). Oxidizes upon prolonged exposure to air and acquires a blue or pink color. Hygroscopic. One gram dissolves in about 3 ml water. Sol in methanol, ethanol, chloroform. Practically insol in ether, benzene. Aq solns are slightly acid to litmus. Incompatible with alkalies, oxidizing agents, heavy metals.
 
Therap-Cat: Antipsychotic.
Therap-Cat-Vet: Tranquilizer.
Keywords: Antipsychotic; Phenothiazines.