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CAS No 54182-58-0 , Sucralfate

  • Name: Sucralfate
  • Synonyms: Sucralfate; Sucrose octasulfate Caluminum complex;Sucrose octasulfate-aluminum complex;
  • CAS Registry Number:
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: g/cm3
  • Flash Point: °C
  • EINECS: 259-018-4
  • Molecular Weight: 2086.74
  • InChI: InChI=1/C12H22O35S8/c13-48(14,15)37-1-4-6(43-51(22,23)24)8(45-53(28,29)30)9(46-54(31,32)33)11(40-4)42-12(3-39-50(19,20)21)10(47-55(34,35)36)7(44-52(25,26)27)5(41-12)2-38-49(16,17)18/h4-11H,1-3H2,(H,13,14,15)(H,16,17,18)(H,19,20,21)(H,22,23,24)(H,25,26,27)(H,28,29,30)(H,31,32,33)(H,34,35,36)/p-8/t4-,5-,6-,7-,8+,9-,10+,11-,12+/m1/s1
  • Molecular Formula: C12H30Al8O51S8.8(H3AlO3)
  • Molecular Structure:CAS No:54182-58-0 Sucralfate
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54182-58-0 sucrose octasulfate - aluminum complex

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54182-58-0 sucrose octasulfate - aluminum complex

  • United States HBCChem, Inc. [Manufacturers]
  • Tel: +1-510-219-6317
  • Fax: +1-510-675-0318
  • Address: Union City,CaliforniaUnited States
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54182-58-0 sucrose octasulfate - aluminum complex

  • China YiPeng Chemical [Manufacturers]
  • Tel: 571 85376369
  • Fax: 571 88233092
  • Address: Building 4,High-tech Industrial Park,No. 588 Feijiatang Road,Xiacheng District, Hangzhou, China ,ZheJiangChina
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54182-58-0 Sucralfate

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 ,United States
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54182-58-0 Sucralfate

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54182-58-0 sucrose octasulfate - aluminum complex

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54182-58-0 A3101 SUCRALFATE

  • United Kingdom Carbosynth Limited [Manufacturer]
  • Tel: +44 (0)1635 578444
  • Fax: +44 (0)1635 579444
  • Address: Carbosynth Limited
    8&9 Old Station Business Park
    Compton
    Berkshire
    RG20 6NE
    UK ,United Kingdom
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54182-58-0 sucrose octasulfate - aluminum complex

  • China Hangzhou Starshine Pharmaceutical Co., LTD [Manufacturers]
  • Tel: +86-571-89939756 85122191
  • Fax: +86-571-85122157
  • Address: ROOM A, 20 TH FLOOR, WEST BUILDING, INTERNATIONAL GARDEN, NO.160 TIANMUSHAN ROAD, HANGZHOU, CHINA ,ZhejiangChina
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54182-58-0 SUCRALFATE

  • United States NetQem, LLC [Manufacturer]
  • Tel: (919) 544-4122
  • Fax: (919) 544-4109
  • Address: NetQem, LLC
    P.O. Box 12091
    Research Triangle Park
    NC 27709, USA ,United States
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54182-58-0 sucrose octasulfate - aluminum complex

  • China KINFON PHARMACEUTICAL AND CHEMICAL CO.LTD [Manufacturer, Trading Company, Distributor/Wholesaler]
  • Tel: +86-23-8650081
  • Fax: +86-23-8650081
  • Address: 7F,Commercial Building, No.3 Nanping West Road,Nan ,China
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References of Sucralfate
Title: Sucralfate
CAS Registry Number: 54182-58-0
CAS Name: Hexadeca-m-hydroxytetracosahydroxy[m8-[1,3,4,6-tetra-O-sulfo-b-D-fructofuranosyl-a-D-glucopyranoside tetrakis(hydrogen sulfato)(8-)]]hexadecaaluminum
Synonyms: b-D-fructofuranosyl-a-D-glucopyranoside octakis(hydrogen sulfate) aluminum complex; sucrose octakis(hydrogen sulfate) aluminum complex
Trademarks: Antepsin (Wyeth); Carafate (Aventis); Citogel (Zyma); Hexagastron (Durascan); Keal (Sinbio); Succosa (Astra HÝsle); Sucralfin (Inverni); Sucrate (Lisapharma); Sugast (Alfa); Sulcrate (Aventis); Ulcar (Houd?; Ulcerlmin (Chugai); Ulcogant (Merck KGaA)
Molecular Formula: C12H54Al16O75S8
Molecular Weight: 2086.74
Percent Composition: C 6.91%, H 2.61%, Al 20.69%, O 57.50%, S 12.29%
Literature References: A basic aluminum sucrose sulfate complex which inhibits peptic hydrolysis and stomach acidity. Prepn: M. Nametaka et al., Yakugaku Zasshi 87, 889 (1967), C.A. 68, 20831d (1968); FR 1500571; N. Yoshihiro et al., US 3432489 (1967, 1969 both to Chugai). Structure and properties: R. Nagashima, N. Yoshida, Arzneim.-Forsch. 29, 1668 (1979). In vitro and in vivo study of antipeptic and antiulcer activity: L. E. Borella, et al., ibid. 793. Series of articles on mode of action: ibid. 30, 73-88 (1980). Pharmacokinetics, metabolism and selective binding studies: K. Steiner et al., ibid. 32, 512 (1982). Clinical studies: J. F. Mayberry et al., Br. J. Clin. Pract. 32, 291 (1978). Symposium on clinical studies: J. Clin. Gastroenterol. 3, Suppl. 2, 103-184 (1981); Scand. J. Gastroenterol. 18, Suppl. 83, 1-82 (1983). Review of pharmacology and clinical studies: R. N. Brogden et al., Drugs 27, 194 (1984). Series of articles on clinical efficacy in peptic ulcer disease and gastritis: Am. J. Med. 79, Suppl. 2C, 1-64 (1985).
Properties: White amorphous powder. Sol in dil HCL and NaOH solns. Practically insol in water, ethanol, CHCl3. pKa = 0.43 to 1.19. Dissolution of aluminum occurs at pH <3; of sucrose sulfate at pH >4.
pKa: pKa = 0.43 to 1.19
Therap-Cat: Antiulcerative.
Keywords: Antiulcerative; Cytoprotectant (Gastric).