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CAS No 53678-77-6 , D-a-Glutamine,N-(N-acetylmuramoyl)-L-alanyl-

  • Name: D-a-Glutamine,N-(N-acetylmuramoyl)-L-alanyl-
  • Synonyms: N-(Acetylmuramoyl)alanyl-D-isoglutamine; N-Acetylmuramyl dipeptide;N-Acetylmuramyl-L-alanine-D-isoGln; MDP;N-(Acetylmuramyl)-L-alanyl-D-isoglutamine;D-a-Glutamine,N2-[N-(N-acetylmuramoyl)-L-alanyl]-; 2: PN: WO2009039971 PAGE: 99 claimedsequence; Acetylmuramyl-L-alanyl-D-isoglutamine; Muramyl dipeptide;D-a-Glutamine,N-(N-acetylmuramoyl)-L-alanyl-;
  • CAS Registry Number:
  • Flash Point: 572.9°C
  • Boiling Point: 1023.7°Cat760mmHg
  • Density: 1.45g/cm3
  • Refractive index: 1.578
  • Safety Statements: S22S24/25
  • Flash Point: 572.9°C
  • EINECS: 258-696-9
  • Molecular Weight: 492.48
  • InChI: InChI=1/C19H32N4O11/c1-7(17(30)23-10(16(20)29)4-5-12(26)27)21-18(31)8(2)33-15-13(22-9(3)25)19(32)34-11(6-24)14(15)28/h7-8,10-11,13-15,19,24,28,32H,4-6H2,1-3H3,(H2,20,29)(H,21,31)(H,22,25)(H,23,30)(H,26,27)/t7-,8+,10+,11+,13+,14+,15+,19+/m0/s1
  • Molecular Formula: C19H32N4O11
  • Molecular Structure:CAS No:53678-77-6 D-a-Glutamine,N-(N-acetylmuramoyl)-L-alanyl-

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53678-77-6 D-a-Glutamine,N-(N-acetylmuramoyl)-L-alanyl-

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53678-77-6 D-a-Glutamine,N-(N-acetylmuramoyl)-L-alanyl-

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53678-77-6 ADJUVANT PEPTIDE

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53678-77-6 321075 N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE HYDRATE ADJUVANT PEPTIDE

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53678-77-6 N-Acetylmuramyl-L-alanyl-D-isoglutamine

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53678-77-6 AC-MURAMYL-ALA-D-GLU-NH2

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References of D-a-Glutamine,N-(N-acetylmuramoyl)-L-alanyl-
Title: Muramyl Dipeptide
CAS Registry Number: 53678-77-6
CAS Name: N-(N-Acetylmuramoyl)-L-alanyl-D-a-glutamine
Synonyms: N-acetylmuramyl-L-alanyl-D-isoglutamine; 2-acetamido-2-deoxy-3-O-(D-2-propionyl-L-alanyl-D-isoglutamine)-D-glucopyranose; MDP
Molecular Formula: C19H32N4O11
Molecular Weight: 492.48
Percent Composition: C 46.34%, H 6.55%, N 11.38%, O 35.74%
Literature References: Synthetic immunoadjuvant corresponding to the smallest immunologically active glycopeptide subunit of the bacterial cell wall. Prepn: A. Adam et al., DE 2450355; eidem, US 4235771 (1975, 1980 both to Agen. Nat. Valor. Recher.); C. Merser et al., Biochem. Biophys. Res. Commun. 66, 1316 (1975); P. Lefrancier et al., Int. J. Pept. Protein Res. 9, 249 (1977). Structure-activity relationships: F. Ellouz et al., Biochem. Biophys. Res. Commun. 59, 1317 (1974); A. Adam et al., ibid. 72, 339 (1976). Review of immunoregulating activity: L. Chedid et al., Prog. Allergy 25, 63-105 (1978). Tissue distribution in mice: M. Parant et al., Int. J. Immunopharmacol. 1, 35 (1979). Potentiation of antitumor immunity: S. Sone et al., J. Biol. Response Modif. 3, 185 (1984); A. E. Eggers, ibid. 7, 229 (1988).
Properties: Crystals from methanol-acetone-ether. [a]D25 +44° (acetic acid).
Optical Rotation: [a]D25 +44° (acetic acid)
Use: Immunological adjuvant.