Home > Name List By 5 > 5-isothiocyanato-2-[(E)-2-(4-isothiocyanato-2-sulfophenyl)ethenyl] benzenesulfonic acid

CAS No 53005-05-3 , 5-isothiocyanato-2-[(E)-2-(4-isothiocyanato-2-sulfophenyl)ethenyl]
benzenesulfonic acid

  • Name: 5-isothiocyanato-2-[(E)-2-(4-isothiocyanato-2-sulfophenyl)ethenyl]
    benzenesulfonic acid
  • Synonyms: 4,4'-Diisothiocyanostilbene-2,2'-disulfonic acid;dids; CHEBI:4286; 4,4'-Diisothiocyanato-2,2'-stilbenedisulfonic acid;5-isothiocyanato-2-[(E)-2-(4-isothiocyanato-2-sulfophenyl)ethenyl]
    benzenesulfonic acid; 53005-05-3;
  • CAS Registry Number:
  • Melting Point: >400°C
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: 1.54g/cm3
  • Refractive index: 1.693
  • Flash Point: °C
  • Molecular Weight: 454.5204
  • InchiKey: YSCNMFDFYJUPEF-OWOJBTEDSA-N
  • InChI: InChI=1S/C16H10N2O6S4/c19-27(20,
    21)15-7-13(17-9-25)5-3-11(15)1-2-12-4-6-14(18-10-26)8-16(12)28(22,
    23)24/h1-8H,(H,19,20,21)(H,22,23,24)/b2-1+
  • Molecular Formula: C16H10N2O6S4
  • Molecular Structure:CAS No:53005-05-3 5-isothiocyanato-2-[(E)-2-(4-isothiocyanato-2-sulfophenyl)ethenyl]<br />benzenesulfonic acid

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References of 5-isothiocyanato-2-[(E)-2-(4-isothiocyanato-2-sulfophenyl)ethenyl]
benzenesulfonic acid
Title: DIDS
CAS Registry Number: 53005-05-3
CAS Name: 2,2￠-(1,2-Ethenediyl)bis[5-isothiocyanatobenzenesulfonic acid]
Synonyms: 4,4￠-diisothiocyanato-2,2￠-stilbenedisulfonic acid
Molecular Formula: C16H10N2O6S4
Molecular Weight: 454.52
Percent Composition: C 42.28%, H 2.22%, N 6.16%, O 21.12%, S 28.22%
Literature References: Classic inhibitor of ion transport across biological membranes. Prepn: Z. I. Cabantchik, A. Rothstein, J. Membr. Biol. 10, 311 (1972); of tritated form: S. Ship et al., ibid. 33, 311 (1977). Inhibition of chloride transport: T. Janas et al., Am. J. Physiol. 257, C601 (1989); J.-A. Kim et al., Biochem. Biophys. Res. Commun. 309, 291 (2003); of non-selective cation conductance: A. Diakov et al., Pflugers Arch. Eur. J. Physiol. 442, 700 (2001). Effects of ionic strength and pH on membrane penetration: V. A. Tverdislov et al., Colloids Surfaces B 5, 205 (1995). Mechanism of inhibition in erythrocytes: J. M. Salhany, Blood Cells Mol. Dis. 27, 901 (2001); of cardiac ryanodine receptor: A. P. Hill, R. Sitsapesan, Biophys. J. 82, 3037 (2002).
Properties: White crystalline solid. uv max: 340 nm (e 16000).
Absorption maximum: uv max: 340 nm (e 16000)
Use: Ion channel inhibitor; especially of anion transport.