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CAS No 53003-10-4 , Salinomycin

  • Name: Salinomycin
  • Synonyms: (2r)-2-((5s)-6-{5-((10s,12r)-2-((6s,5r)-5-ethyl-5-hydroxy-6-methylperhydro-2h-pyran-2-yl)-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro(4.1.5.3)pentadec-13-en-9-yl)(1s,2s,3s,5r)-2-hydroxy-1,3-dimethyl-4-oxoheptyl}-5-methylperhydro-2h-pyran-2-yl)butanoic acid;(2R)-2-((5S)-6-{5-[(10S,12R)-2-((6S,5R)-5-Ethyl-5-hydroxy-6-methylperhydro-2H-pyran-2-yl)-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[4.1.5.3]pentadec-13-en-9-yl](1S,2S,3S,5R)-2-hydroxy-1,3-dimethyl-4-oxoheptyl}-5-methylperhydro-2H-pyran-2-yl)butanoic acid;Salinomycin;
  • CAS Registry Number:
  • Transport: UN 3462
  • Melting Point: 112.5-113.5 ºC
  • Density: 1.18 g/cm3
  • Water Solubility: Soluble in ethanol
  • Safety Statements: R25
  • Hazard Symbols: T: Toxic;
  • EINECS: 258-290-1
  • Molecular Weight: 751.01
  • InChI: InChI=1/C42H70O11/c1-11-29(38(46)47)31-15-14-23(4)36(50-31)27(8)34(44)26(7)35(45)30(12-2)37-24(5)22-25(6)41(51-37)19-16-32(43)42(53-41)21-20-39(10,52-42)33-17-18-40(48,13-3)28(9)49-33/h16,19,23-34,36-37,43-44,48H,11-15,17-18,20-22H2,1-10H3,(H,46,47)/t23-,24-,25+,26-,27-,28-,29+,30-,31?,32+,33+,34+,36+,37-,39-,40+,41+,42+/m0/s1
  • Risk Statements: S45
  • Molecular Formula: C42H70O11
  • Molecular Structure:CAS No:53003-10-4 Salinomycin

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53003-10-4 Salinomycin

  • "Appearance White or light yellow crystalline powder Identification Coloration with vanillin positive(red) UV spectrum absorption Maximun absorption at 285~300nm Particle size 850μm : ≥100% Loss on drying 7.0% max Residue on ignition 7.0%~11.0% Hea...
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53003-10-4 Salinomycin

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53003-10-4 Salinomycini

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53003-10-4 Salinomycin

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53003-10-4 Salinomycin

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53003-10-4 Salinomycin

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53003-10-4 SALINOMYCIN

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53003-10-4 Salinomycin Sodium

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53003-10-4 Salinomycin

  • United States CBSCHEM LIMITED null
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References of Salinomycin
Title: Salinomycin
CAS Registry Number: 53003-10-4
Molecular Formula: C42H70O11
Molecular Weight: 751.00
Percent Composition: C 67.17%, H 9.39%, O 23.43%
Literature References: Polyether ionophoric antibiotic having a unique tricyclic spiroketal ring system and an unsaturated 6-membered ring in the molecule. Produced by a strain of Streptomyces albus (FERM-P No. 419 and ATCC 21838). Production: Y. Miyazaki et al., JP Kokai 72 25392 (1972 to Kaken Chem.), C.A. 78, 41561 (1973). Structure: H. Kinashi et al., Tetrahedron Lett. 1973, 4955. Taxonomy, production, isolation and physicochemical and biological properties: Y. Miyazaki et al., J. Antibiot. 27, 814 (1974). Use as a coccidiostat: Y. Tanaka et al., DE 2253031; eidem, US 3857948 (1973, 1974 to Kaken Chem.). Anticoccidial efficacy: T. T. Migaki et al., Poult. Sci. 58, 1192 (1979). Total synthesis: Y. Kishi et al., Front. Chem., Plenary Keynote Lect. IUPAC Congr., 28th 1981, K. J. Laidler, Ed. (Pergamon, Oxford, 1982) pp 287-304; R. C. D. Brown, P. J. Kocienski, Synlett 1994, 415, 417. HPLC determn in animal feeds: M. R. LaPointe, H. Cohen, J. Assoc. Off. Anal. Chem. 71, 480 (1988).
Properties: mp 112.5-113.5°. pKa￠ 6.4 (DMF). [a]D25 -63° (c = 1 in ethanol). uv max (ethanol-water, 2:1): 284 nm (e 126). LD50 in mice (mg/kg): 18 i.p.; 50 orally (Miyazaki).
Melting point: mp 112.5-113.5°
pKa: pKa￠ 6.4 (DMF)
Optical Rotation: [a]D25 -63° (c = 1 in ethanol)
Absorption maximum: uv max (ethanol-water, 2:1): 284 nm (e 126)
Toxicity data: LD50 in mice (mg/kg): 18 i.p.; 50 orally (Miyazaki)
 
Derivative Type: Sodium salt
CAS Registry Number: 55721-31-8
Trademarks: Bio-Cox (Alpharma); Sacox (Intervet); Salocin (Intervet)
Molecular Formula: C42H69NaO11
Molecular Weight: 772.98
Percent Composition: C 65.26%, H 9.00%, Na 2.97%, O 22.77%
Properties: mp 140-142°. [a]D25 -37° (c = 1 in ethanol).
Melting point: mp 140-142°
Optical Rotation: [a]D25 -37° (c = 1 in ethanol)
 
Therap-Cat-Vet: Anticoccidial agent.