Title: Kinetin
CAS Registry Number: 525-79-1
CAS Name: N-(2-Furanylmethyl)-1
H-purin-6-amine
Synonyms: N6-furfuryladenine; 6-furfurylaminopurine
Molecular Formula: C10H9N5O
Molecular Weight: 215.21
Percent Composition: C 55.81%, H 4.22%, N 32.54%, O 7.43%
Literature References: A cell division factor found in various plant parts and in yeast. Isoln from autoclaved water slurries of deoxyribonucleic acid: Miller
et al., J. Am. Chem. Soc. 77, 1392 (1955). Structure and synthesis from furfurylamine and 6-methylmercaptopurine: Miller
et al., ibid. 2662;
78, 1375 (1956);
US 2903455 (1959 to Wisc. Alumni Res. Found.). Physiologically active at very great dilutions, but only in presence of auxin,
see Indoleacetic Acid. Crystal structure: M. Soriano-Garcia, R. Parthasarathy,
Acta Crystallogr. 33B, 2674 (1977).
Review: Miller,
Annu. Rev. Plant Physiol. 12, 395 (1961).
Properties: Platelets from abs ethanol, mp 266-267° (sealed tube). Sublimes at 220°. pKa1 2.7; pKa2 9.9. uv max (ethanol): 268 nm (e 18,650). Slightly soluble in cold water, methanol, ethanol. Freely soluble in dil aq HCl or NaOH. Can be extracted from neutral aq solns by shaking with ether.
Melting point: mp 266-267° (sealed tube)
pKa: pKa1 2.7; pKa2 9.9
Absorption maximum: uv max (ethanol): 268 nm (e 18,650)
NOTE: Kinetin is also a brand of hyaluronidase,
q.v.
Use: Plant growth regulator. To augment growth of microbial cultures:
BE 632589 (1963 to Hoechst).