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CAS No 516-21-2 , 1,3,5-Triazine-2,4-diamine,1-(4-chlorophenyl)-1,6-dihydro-6,6-dimethyl-

  • Name: 1,3,5-Triazine-2,4-diamine,1-(4-chlorophenyl)-1,6-dihydro-6,6-dimethyl-
  • Synonyms: 1,3,5-Triazine-2,4-diamine,1-(4-chlorophenyl)-1,6-dihydro-6,6-dimethyl-; Chlorazin;s-Triazine,4,6-diamino-1-(p-chlorophenyl)-1,2-dihydro-2,2-dimethyl- (6CI,8CI); Cycloguanyl; D 20; WR 5473;4,6-Diamino-1-(p-chlorophenyl)-1,2-dihydro-2,2-dimethyl-s-triazine;Chlorazine;TCl; Chlorguanide triazine; M 10580;1-(p-Chlorophenyl)-1,2-dihydro-2,2-dimethyl-4,6-diamino-s-triazine; 1-(4-Chlorophenyl)-4,6-diamino-1,2-dihydro-2,2-dimethyl-1,3,5-triazine; Cycloguanil;
  • CAS Registry Number:
  • Flash Point: 196.1°C
  • Boiling Point: 400.7°Cat760mmHg
  • Density: 1.4g/cm3
  • Safety Statements: Poison by intraperitoneal route. An experimental teratogen. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.
  • Flash Point: 196.1°C
  • Molecular Weight: 251.75
  • InChI: InChI=1/C11H14ClN5/c1-11(2)16-9(13)15-10(14)17(11)8-5-3-7(12)4-6-8/h3-6H,1-2H3,(H4,13,14,15,16)
  • Molecular Formula: C11H14 Cl N5
  • Molecular Structure:CAS No:516-21-2 1,3,5-Triazine-2,4-diamine,1-(4-chlorophenyl)-1,6-dihydro-6,6-dimethyl-
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516-21-2 Cycloguanil

  • Cycloguanil, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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516-21-2 Cycloguanil

  • Cycloguanil, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,nullChina
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516-21-2 CYCLOGUANIL-D6

  • India VARDA Biotech (P) Ltd. [Manufacturer]
  • Tel: +91-22-6693 5686 / 2673 0141 / 2673 4258
  • Fax: +91-22-6693 5687
  • Address: 110 & 111, Kartik Complex
    New link Road, Andheri-(W)
    Mumbai-400053, INDIA. null,nullIndia
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516-21-2 CYCLOGUANIL HCL

  • United States EJY Tech, Inc. [Manufacturer]
  • Tel: 301-526-7059
  • Fax: 301-561-6521
  • Address: 9430 Key West Avenue
    Suite 220
    Rockville , MD 20850 null,nullUnited States
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516-21-2 CYCLOGUANIL HCL

  • Canada SynFine Research Inc. [Manufacturer]
  • Tel: 905-737-2702
  • Fax: 905-737-6299
  • Address: SynFine Research Inc.
    P.O. Box 433 ? Station A
    Richmond Hill, ON L4C 4Y8
    Canada null,nullCanada
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516-21-2 CYCLOGUANIL

  • Canada TLC PharmaChem., Inc. [Manufacturer]
  • Tel: 905-760-1098
  • Fax: 905-760-2098
  • Address: TLC PharmaChem., Inc.
    5-150 Connie Crescent
    Concord, Ontario
    L4K 1L9, Canada null,nullCanada
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516-21-2 CYCLOGUANIL

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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References of 1,3,5-Triazine-2,4-diamine,1-(4-chlorophenyl)-1,6-dihydro-6,6-dimethyl-
Title: Cycloguanil
CAS Registry Number: 516-21-2
CAS Name: 1-(4-Chlorophenyl)-1,6-dihydro-6,6-dimethyl-1,3,5-triazine-2,4-diamine
Synonyms: 4,6-diamino-1-(p-chlorophenyl)-1,2-dihydro-2,2-dimethyl-s-triazine; 2,4-diamino-1-p-chlorophenyl-1,6-dihydro-6,6-dimethyl-1,3,5-triazine; 1-p-chlorophenyl-2,4-diamino-6,6-dimethyl-1,6-dihydro-1,3,5-triazine; chlorazine (Russian); chlorguanide triazine; TCl
Manufacturers' Codes: M-10580; D-20
Molecular Formula: C11H14ClN5
Molecular Weight: 251.72
Percent Composition: C 52.49%, H 5.61%, Cl 14.08%, N 27.82%
Literature References: Metabolic product formed from the antimalarial drug chlorguanide: Carrington et al., Nature 168, 1080 (1951). Prepn: Modest et al., J. Am. Chem. Soc. 74, 855 (1952); Loo, ibid. 76, 5096 (1954); Carrington et al., J. Chem. Soc. 1954, 1017; Bami, J. Sci. Ind. Res. 14C, 231 (1955); Modest, J. Org. Chem. 21, 1 (1956); US 2900385 (1959 to Children's Cancer Res. Found.); Elslager, Worth, US 3074947 (1963 to Parke, Davis).
Properties: Prisms from chloroform + ether, mp 146°. uv max (water): 241 nm (log e 4.11).
Melting point: mp 146°
Absorption maximum: uv max (water): 241 nm (log e 4.11)
 
Derivative Type: Hydrochloride
Molecular Formula: C11H14ClN5.HCl
Molecular Weight: 288.18
Percent Composition: C 45.85%, H 5.25%, Cl 24.60%, N 24.30%
Properties: Prisms from water, mp 210-215°. uv max (water): 241 nm (log e 4.12).
Melting point: mp 210-215°
Absorption maximum: uv max (water): 241 nm (log e 4.12)
 
Derivative Type: Dihydrochloride
Molecular Formula: C11H14ClN5.2HCl
Molecular Weight: 324.64
Percent Composition: C 40.70%, H 4.97%, Cl 32.76%, N 21.57%
Properties: Crystals from acetone, mp 190-196°.
Melting point: mp 190-196°
 
Derivative Type: Pamoate
CAS Registry Number: 609-78-9
Synonyms: Cycloguanil embonate
Manufacturers' Codes: CI-501
Trademarks: Camolar (Parke-Davis)
Molecular Formula: (C11H14ClN5)2.C23H16O6
Molecular Weight: 891.80
Percent Composition: C 60.61%, H 4.97%, Cl 7.95%, N 15.71%, O 10.76%
Properties: Yellow crystals, mp 231-234°. Soly in water: 0.003%.
Melting point: mp 231-234°
 
Therap-Cat: Antimalarial.
Keywords: Antimalarial.