Home > Name List By 5 > 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine

CAS No 51322-75-9 , 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine

  • Name: 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine
  • Synonyms: Tizanidinum; Tizanidinum [INN-Latin]; Tizanidine (INN);Sirdalud; Sirdalud (TN); 51322-75-9; Tizanidina [INN-Spanish]; Ternelin; Tizanidina;5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine;
  • CAS Registry Number:
  • Melting Point: 221 - 223
  • Density: 1.82 g/cm3
  • Water Solubility: H2O: ~29 mg/mL
  • Safety Statements: 26-36
  • Hazard Symbols: Xn: Harmful;
  • Molecular Weight: 253.71132
  • InchiKey: XFYDIVBRZNQMJC-UHFFFAOYSA-N
  • InChI: InChI=1S/C9H8ClN5S/c10-5-1-2-6-8(15-16-14-6)7(5)13-9-11-3-4-12-9/h1-2H,
    3-4H2,(H2,11,12,13)
  • Risk Statements: 22-36/37/38
  • Molecular Formula: C9H8ClN5S
  • Molecular Structure:CAS No:51322-75-9 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine
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51322-75-9 TIZANIDINE-D4

  • India VARDA Biotech (P) Ltd. [Manufacturer]
  • Tel: +91-22-6693 5686 / 2673 0141 / 2673 4258
  • Fax: +91-22-6693 5687
  • Address: 110 & 111, Kartik Complex
    New link Road, Andheri-(W)
    Mumbai-400053, INDIA. null,nullIndia
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51322-75-9 2,1,3-Benzothiadiazol-4-amine,5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-

  • China VETCHEM Biochemistry Science [Manufacturer, Distributor/Wholesaler]
  • Tel: +86-21-593837
  • Address: No.2 Jinshanwei Industrial Zon,Shanghai 200120 China Shanghai,ShanghaiChina
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51322-75-9 TIZANIDINE HCL

  • Canada Synth?se AptoChem Inc. [Manufacturer]
  • Tel: 514-496-4252
  • Fax: 514-496-4253
  • Address: Synth?se AptoChem Inc.
    6100 Royalmount Ave
    Montreal, QC
    Canada
    H4P 2R2 null,nullCanada
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51322-75-9 Tizanidine

  • India Exim-Pharm International null
  • Tel: +91-(22)-26191948
  • Fax: +91-(22)-26191948
  • Address: 1, Ashish Mahal, 2nd Floor, Ist Road, Golibar Santacruz (E), Mumbai, Maharashtra 400 055, null,nullIndia
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51322-75-9 tizanidine

  • China Borun Chemical Co.,Ltd. [Manufacturers]
  • Tel: +86-574- 87178138;87297407
  • Fax: 86-574-87296297
  • Address: Unit 809, Liuting Xingzuo, Cangsong Road, Ningbo, China null,zhejiangChina
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51322-75-9 Tizanidine

  • China Zibo Wanchang Group [Manufacturers]
  • Tel: +86-(533)-298-8888
  • Fax: +86-(533)-209-1578
  • Address: 17 Zhaoyang Road, Zibo, Shandong 255068, Zibo,ShandongChina
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51322-75-9 2,1,3-Benzothiadiazol-4-amine,5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-

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51322-75-9 Tizanidine USP

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51322-75-9 SC-200148 TIZANIDINE HCL

  • United States Santa Cruz Biotechnology, Inc. [Manufacturer]
  • Tel: 831-457-3800/ 800-457-3801
  • Fax: 831-457-3801
  • Address: Santa Cruz Biotechnology, Inc.
    2145 Delaware Ave.
    Santa Cruz, CA 95060 null,nullUnited States
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51322-75-9 2,1,3-Benzothiadiazol-4-amine,5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-

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References of 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine
Title: Tizanidine
CAS Registry Number: 51322-75-9
CAS Name: 5-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine
Synonyms: 5-chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazole
Molecular Formula: C9H8ClN5S
Molecular Weight: 253.71
Percent Composition: C 42.61%, H 3.18%, Cl 13.97%, N 27.60%, S 12.64%
Literature References: a2-Adrenergic agonist; centrally active myotonolytic. Prepn and antitremor activity: P. Neumann, NL 7306228; eidem, US 3843668 (1973, 1974 both to Wander-Sandoz). Pharmacology: A. C. Sayers et al., Arzneim.-Forsch. 30, 793 (1980); and mechanism of action studies: L. Turski et al., Brain Res. 379, 367 (1986); H. Ono et al., Gen. Pharmacol. 17, 137 (1986). Pharmacokinetics: V. Heazlewood et al., Eur. J. Clin. Pharmacol. 25, 65 (1983). Clinical evaluation in spasticity of multiple sclerosis: P. M. Newman et al., ibid. 23, 31 (1982); M. C. Hoogstraten et al., Acta Neurol. Scand. 77, 224 (1988).
Properties: Crystals from methanol, mp 221-223°. LD50 orally in mice: 235 mg/kg (Sayers).
Melting point: mp 221-223°
Toxicity data: LD50 orally in mice: 235 mg/kg (Sayers)
 
Derivative Type: Hydrochloride
CAS Registry Number: 64461-82-1
Manufacturers' Codes: AB-021; DS-103-282
Trademarks: Sirdalud (Novartis); Ternelin (Novartis); Zanaflex (Athena)
Molecular Formula: C9H8ClN5S.HCl
Molecular Weight: 290.17
Percent Composition: C 37.25%, H 3.13%, Cl 24.44%, N 24.14%, S 11.05%
 
Therap-Cat: Muscle relaxant (skeletal).
Keywords: Muscle Relaxant (Skeletal).