Title: Tyramine
CAS Registry Number: 51-67-2
CAS Name: 4-(2-Aminoethyl)phenol
Synonyms: 4-hydroxyphenethylamine; tyrosamine; 2-
p-hydroxyphenylethylamine;
p-b-aminoethylphenol; a-(4-hydroxyphenyl)-b-aminoethane
Molecular Formula: C8H11NO
Molecular Weight: 137.18
Percent Composition: C 70.04%, H 8.08%, N 10.21%, O 11.66%
Literature References: Decarboxylation product of tyrosine. Found in mistletoes, putrefied animal tissue, ripe cheese, ergot. Synthesis: Barger,
J. Chem. Soc. 95, 1127 (1909); Waser,
Helv. Chim. Acta 8, 766 (1925); Buck,
J. Am. Chem. Soc. 55, 3389 (1933). Crystal and molecular structure: A. Podder
et al., Acta Crystallogr. B35, 649 (1979).
Properties: Crystals from benzene or alcohol, mp 164-165°. bp25 205-207°; bp2 166°. Alkaline reaction. One gram dissolves in 95 ml water at 15°; in 10 ml boiling alcohol. Sparingly sol in benzene, xylene.
Melting point: mp 164-165°
Boiling point: bp25 205-207°; bp2 166°
Derivative Type: Hydrochloride
CAS Registry Number: 60-19-5
Trademarks: Mydrial (Winzer)
Molecular Formula: C8H11NO.HCl
Molecular Weight: 173.64
Percent Composition: C 55.34%, H 6.97%, N 8.07%, O 9.21%, Cl 20.42%
Properties: Crystals from alcohol + ether, mp 269°. Sol in water with neutral reaction.
Melting point: mp 269°
Therap-Cat: Adrenergic.
Keywords: a-Adrenergic Agonist.