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CAS No 51-45-6 , 2-(1H-imidazol-5-yl)ethanamine

  • Name: 2-(1H-imidazol-5-yl)ethanamine
  • Synonyms: 1H-Imidazole-4-ethanamine; 51-45-6;2-(1H-imidazol-5-yl)ethanamine; 5-Imidazoleethylamine; Eramin; Ergotidine; 2-(4-Imidazolyl)ethylamine; Theramine; Ergamine;
  • CAS Registry Number:
  • Transport: UN 2811
  • Melting Point: 83-84 ºC
  • Flash Point: 180.3°C
  • Boiling Point: 167 ºC (0.8 MMHG)
  • Density: 1.14g/cm3
  • Refractive index: 1.562
  • Safety Statements: R22;R36/37/38;R42/43
  • Hazard Symbols: Xn: Harmful;
  • Flash Point: 180.3°C
  • EINECS: 200-100-6
  • Molecular Weight: 111.14506
  • InchiKey: NTYJJOPFIAHURM-UHFFFAOYSA-N
  • InChI: InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)
  • Risk Statements: S22;S26;S36/37
  • Molecular Formula: C5H9N3
  • Molecular Structure:CAS No:51-45-6 2-(1H-imidazol-5-yl)ethanamine
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51-45-6 HISTAMINE, FREE BASE

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong ,Hong kong
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51-45-6 2-imidazol-4-ylethylamine

  • United States HBCChem, Inc. [Manufacturers]
  • Tel: +1-510-219-6317
  • Fax: +1-510-675-0318
  • Address: Union City,CaliforniaUnited States
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51-45-6 L-HISTAMIN BASE

  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany ,Germany
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51-45-6 HISTAMINE 96%

  • United States Advanced Synthesis Technologies [Manufacturer]
  • Tel: 619-423-7821
  • Fax: 619-423-7793
  • Address: Advanced Synthesis
    P.O. Box 437920
    San Ysidro, CA 92173 ,United States
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51-45-6 2-imidazol-4-ylethylamine

  • China Modachem Shanghai Co., Ltd. [Manufacturers]
  • Tel: 021-51371369
  • Fax: 021-51371369
  • Address: zhangjiang, Shanghai 200230, P.R.China shanghai,shanghaiChina
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51-45-6 HISTAMINE

  • Germany Cfm Oskar Tropitzsch [Manufacturer]
  • Tel: +49-9231-9619-0
  • Fax: +49-9231-9619-60
  • Address: Cfm Oskar Tropitzsch
    Waldershofer Str. 49-51
    95615 Marktredwitz
    Germany ,Germany
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51-45-6 2-imidazol-4-ylethylamine

  • China Shanghai FWD Chemicals Co., Ltd. [Manufacturers]
  • Tel: 86 21-64251365
  • Fax: +86-21- 54293447
  • Address: Shanghai FWD Chemicals Limited Meilong Rd 428, Suite 1501Lingyun ApartmentXuhui District, Shanghai, 200237, P.R.China Shanghai,ShanghaiChina
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51-45-6 HISTAMINE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China ,China
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References of 2-(1H-imidazol-5-yl)ethanamine
Title: Histamine
CAS Registry Number: 51-45-6
CAS Name: 1H-Imidazole-4-ethanamine
Synonyms: 2-(4-imidazolyl)ethylamine; 4-imidazoleethylamine; 5-imidazoleethylamine; b-aminoethylimidazole; b-aminoethylglyoxaline
Molecular Formula: C5H9N3
Molecular Weight: 111.15
Percent Composition: C 54.03%, H 8.16%, N 37.80%
Literature References: Biogenic amine widely distributed in nature; decarboxylation product of histidine, q.v. Present in most mammalian tissues; primarily stored in mast cells and basophils. Exhibits multiple biological effects through at least 3 specific receptors. Induces bronchoconstriction and vasodilation; stimulates gastric acid secretion; and acts as a neurotransmitter. Synthesis: A. Windaus, W. Vogt, Ber. 40, 3691 (1907); F. L. Pyman, J. Chem. Soc. 101, 530 (1912). Identification as vasodilator: H. H. Dale, P. P. Laidlaw, J. Physiol. 41, 318 (1910). Toxicity data: K. Nagai et al., Arzneim.-Forsch. 17, 1575 (1967). Diagnostic use in pheochromocytoma: T. Nakai, R. Yamada, J. Clin. Endocrinol. Metab. 57, 19 (1983); in airway responsiveness: A. James, G. Ryan, Respirology 2, 97 (1997). Clinical efficacy in combination with interleukin-2, q.v., in treatment of acute myelogenous leukemia: K. Hellstrand et al., Leuk. Lymphoma 27, 429 (1997). Mechanism of antineoplastic activity: eidem, Acta Oncol. 37, 347 (1998). Review of assay methods for determn in plasma: E. Oosting et al., Clin. Exp. Allergy 20, 349-357 (1990). Review of role in allergic disease: M. V. White, J. Allergy Clin. Immunol. 86, 599-605 (1990); in gastric acid secretion: K. J. Obrink, Scand. J. Gastroenterol. 26, Suppl. 180, 4-8 (1991); in homeostatic energy metabolism: T. Sakata et al., Nutrition 13, 403-411 (1997). Review of pharmacology and classification of receptors: S. J. Hill et al., Pharmacol. Rev. 49, 253-278 (1997).
Properties: Deliquescent needles from chloroform, mp 83-84°. bp18 209-210°. Freely sol in water, alcohol, hot chloroform. Practically insol in ether. LD50 i.p. in mice: 2020 mg/kg (Nagai).
Melting point: mp 83-84°
Boiling point: bp18 209-210°
Toxicity data: LD50 i.p. in mice: 2020 mg/kg (Nagai)
 
Derivative Type: Dihydrochloride
CAS Registry Number: 56-92-8
Trademarks: Maxamine (Maxim)
Molecular Formula: C5H9N3.2HCl
Molecular Weight: 184.07
Percent Composition: C 32.63%, H 6.02%, N 22.83%, Cl 38.52%
Properties: Prisms from ethanol, mp 244-246°. Freely sol in water, methanol; sol in ethanol.
Melting point: mp 244-246°
 
Derivative Type: Phosphate
CAS Registry Number: 51-74-1
Molecular Formula: C5H9N3.2H3PO4
Molecular Weight: 307.14
Percent Composition: C 19.55%, H 4.92%, N 13.68%, P 20.17%, O 41.67%
Properties: Clear, colorless prisms from water, mp 132-133°. Readily sol in hot water.
Melting point: mp 132-133°
 
Therap-Cat: Antineoplastic (immunomodulator); diagnostic aid (gastric secretion, pheochromocytoma, bronchial hyperreactivity).
Keywords: Antiallergic (Hyposensitization Therapy); Diagnostic Aid.