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CAS No 51-41-2 , 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol

  • Name: 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol
  • Synonyms: Levophed; Arterenol;4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol; L-Noradrenaline;noradrenaline; L-Norepinephrine; (-)-Norepinephrine; L-arterenol; Levarterenol;
  • CAS Registry Number:
  • Transport: UN 2811
  • Melting Point: 220-230°C
  • Density: 1.397 g/cm3
  • Refractive index: 1.66
  • Safety Statements: R26/27/28
  • Hazard Symbols: T+: Very toxic;
  • EINECS: 200-096-6
  • Molecular Weight: 169.17784
  • InchiKey: SFLSHLFXELFNJZ-QMMMGPOBSA-N
  • InChI: InChI=1S/C8H11NO3/c9-4-8(12)5-1-2-6(10)7(11)3-5/h1-3,8,10-12H,4,
    9H2/t8-/m0/s1
  • Risk Statements: S28;S36/37;S45
  • Molecular Formula: C8H11NO3
  • Molecular Structure:CAS No:51-41-2 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol
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  • Product name:Norepinephrine CAS No.:51-41-2 Molecular formula:C8H11NO3 Molecular weight:169.18 Product Specifications:Pharmacopoeial grade Purity:99%+ Email: dahuasales02@whdhwy.com WhatApp/WeChat:+86 15623424115
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51-41-2 Norepinephrine

  • Norepinephrine Synonyms: (-)-alpha-(aminomethyl)protocatechuylalcohol;(-)-noradrec;4-(2-amino-1-hydroxyethyl)-2-benzenedio(r)-;adrenor;aktamin;arterenolfreebase(noradrenaline);d-(-)-noradrenaline;l-1-(3,4-dihydroxyphenyl)-2-aminoethanol CAS: 51-41-2 ...
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51-41-2 Norepinephrine(NE,NA,norepi )

  • CAS:51-41-2 EINECS:205-750-4 MF:C8H11NO3 MW:169.18 Purity:98%min Appearance:White or Off-white crystal powder Flash(ing) Point:190.9℃ Boiling Point:392.1℃ at 760 mmHg Melting Point:100℃-106℃。 Density:1.402g/cm3 Description:Norepinephrine (INN) (...
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51-41-2 L-NORADRENALINE; 98%

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51-41-2 Norepinephrine

  • IUPAC NAME-4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol MOLECULAR FORMULA-C8H11NO3 MOLAR MASS-169.18 g mol orepinephrine or noradrenaline is a catecholamine with multiple roles including as a hormone and a neurotransmitter.[3] It is the hormone an...
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  • L-NORADRENALINE, 98%
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51-41-2 Norepinephrine

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References of 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol
Title: Norepinephrine
CAS Registry Number: 51-41-2
CAS Name: 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol
Synonyms: (-)-a-(aminomethyl)-3,4-dihydroxybenzyl alcohol; l-3,4-dihydroxyphenylethanolamine; noradrenaline; levarterenol
Trademarks: Adrenor; Levophed (Winthrop)
Molecular Formula: C8H11NO3
Molecular Weight: 169.18
Percent Composition: C 56.79%, H 6.55%, N 8.28%, O 28.37%
Literature References: Demethylated precursor of epinephrine, q.v. Occurs in animals and man, and is a sympathomimetic hormone of both adrenal origin and adrenergic orthosympathetic postganglionic origin in man. Physiologic review: Malmejac, Physiol. Rev. 44, 186 (1964). It has also been found in plants, e.g., Portulaca olerocea L., Portulacaceae: Fing et al., Nature 191, 1108 (1961). Synthesis of dl-form: Payne, Ind. Chem. 37, 523 (1961). Historic review of synthesis: Loewe, Arzneim.-Forsch. 4, 583 (1954). Resolution of dl-form: Tullar, J. Am. Chem. Soc. 70, 2067 (1948); idem, US 2774789 (1956 to Sterling Drug). Configuration: Pratesi et al., J. Chem. Soc. 1959, 4062. Comprehensive description: C. F. Schwender, Anal. Profiles Drug Subs. 1, 149-173 (1972); T. D. Wilson, ibid. 11, 555-586 (1982).
Properties: Microcrystals, dec 216.5-218°. [a]D25 -37.3° (c = 5 in water with 1 equiv HCl).
Optical Rotation: [a]D25 -37.3° (c = 5 in water with 1 equiv HCl)
 
Derivative Type: Hydrochloride
CAS Registry Number: 329-56-6
Trademarks: Arterenol (HMR)
Molecular Formula: C8H11NO3.HCl
Molecular Weight: 205.64
Percent Composition: C 46.73%, H 5.88%, N 6.81%, O 23.34%, Cl 17.24%
Properties: Crystals, mp 145.2-146.4°. [a]D25 -40° (c = 6). Freely sol in water. Solns slowly oxidize under the influence of light and oxygen in a manner comparable to epinephrine hydrochloride.
Melting point: mp 145.2-146.4°
Optical Rotation: [a]D25 -40° (c = 6)
 
Derivative Type: d-Bitartrate
CAS Registry Number: 69815-49-2
Synonyms: Levarterenol bitartrate
Trademarks: Aktamin; Binodrenal
Molecular Formula: C8H11NO3.C4H6O6
Molecular Weight: 319.26
Percent Composition: C 45.14%, H 5.37%, N 4.39%, O 45.10%
Properties: Obtained as the monohydrate, crystals, mp 102-104°. [a]D25 -10.7° (c = 1.6 in H2O). When anhydr, mp 158-159° (some decompn). Freely sol in water.
Melting point: mp 102-104°; mp 158-159° (some decompn)
Optical Rotation: [a]D25 -10.7° (c = 1.6 in H2O)
 
Derivative Type: dl-Form
Properties: Crystals, dec 191°. Sparingly sol in water; very slightly sol in alc, ether; readily sol in dilute acids, caustic.
 
Therap-Cat: Adrenergic (vasopressor); antihypotensive.
Therap-Cat-Vet: Sympathomimetic; vasopressor in shock.
Keywords: a-Adrenergic Agonist; Antihypotensive.