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CAS No 5053-06-5 , 8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one

  • Name: 8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
  • Synonyms: 5053-06-5; Fenspirida [INN-Spanish];8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one;Respiride; Viarespan; Fenspiride (INN); Fenspiridum [INN-Latin]; EINECS 225-751-3; Fenspiride [INN];
  • CAS Registry Number:
  • Flash Point: 240.6°C
  • Boiling Point: 474.3°Cat760mmHg
  • Density: 1.19g/cm3
  • Refractive index: 1.591
  • Flash Point: 240.6°C
  • EINECS: 225-751-3
  • Molecular Weight: 260.3315
  • InchiKey: FVNFBBAOMBJTST-UHFFFAOYSA-N
  • InChI: InChI=1S/C15H20N2O2/c18-14-16-12-15(19-14)7-10-17(11-8-15)9-6-13-4-2-1-
    3-5-13/h1-5H,6-12H2,(H,16,18)
  • Molecular Formula: C15H20N2O2
  • Molecular Structure:CAS No:5053-06-5 8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one

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  • Name Fenspiride Synonyms 8-Phenethyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one Molecular Formula C15H20N2O2 Molecular Weight 260.34 CAS Registry Number 5053-06-5 EINECS 225-751-3 Assay:98.5%min Indication: Anti asthma and chronic bronchitis
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References of 8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
Title: Fenspiride
CAS Registry Number: 5053-06-5
CAS Name: 8-(2-Phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
Synonyms: decaspiride; DESP
Molecular Formula: C15H20N2O2
Molecular Weight: 260.33
Percent Composition: C 69.20%, H 7.74%, N 10.76%, O 12.29%
Literature References: a-Adrenergic blocker. Prepn: NL 6504602; Regnier et al., US 3399192 (1965 and 1968, both to Sci. Union et Cie-Soc. Franc. Recherche Méd.). Pharmacology: LeDouarec et al., Arzneim.-Forsch. 19, 1263 (1969); Duhault et al., ibid. 22, 1947 (1972).
 
Derivative Type: Hydrochloride
CAS Registry Number: 5053-08-7
Manufacturers' Codes: NAT-333; NDR-5998A
Trademarks: Decaspir (Pulitzer); Fluiden (Lafare); Pneumorel (Stroder); Respiride (Schiapparelli); Tegencia (Elmu); Viarespan (Servier)
Molecular Formula: C15H20N2O2.HCl
Molecular Weight: 296.79
Percent Composition: C 60.70%, H 7.13%, N 9.44%, O 10.78%, Cl 11.95%
Properties: Crystals decomp 232-233°. Soluble in water. LD50 i.v. in mice: 106 mg/kg; orally in rats: 437 mg/kg (LeDouarec).
Toxicity data: LD50 i.v. in mice: 106 mg/kg; orally in rats: 437 mg/kg (LeDouarec)
 
Therap-Cat: Bronchodilator.
Keywords: a-Adrenergic Blocker; Bronchodilator.