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CAS No 50-81-7 , (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one

  • Name: (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one
  • Synonyms: Cebione; Ascorbicap; Cecon; Cevalin; ascorbate;(2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one; vitamin C; Ascoltin; Cevex;l-ascorbic acid;
  • CAS Registry Number:
  • Melting Point: 190-192 ºC
  • Density: 1,65 g/cm3
  • Refractive index: 21 ° (C=10, H2O)
  • Alpha: 20.5 º (C=10,H2O)
  • Water Solubility: 333 G/L (20 ºC)
  • Safety Statements: S24/25
  • Hazard Symbols: Xn
  • EINECS: 200-066-2
  • Molecular Weight: 176.12412
  • InchiKey: CIWBSHSKHKDKBQ-JLAZNSOCSA-N
  • InChI: InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,
    5+/m0/s1
  • Risk Statements: S24/25
  • Molecular Formula: C6H8O6
  • Molecular Structure:CAS No:50-81-7 (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one
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50-81-7 L(+)-Ascorbic acid

  • L(+)-Ascorbic acid Synonyms:3-Keto-L-gulofuranolactone;3-Oxo-L-gulofuranolactone;3-oxo-l-gulofuranolactone(enolform);Adenex;Allercorb;Antiscorbic vitamin;antiscorbicvitamin;Antiscorbutic vitamin CAS:50-81-7 MF:C6H8O6 MW:176.12 EINECS:200-066-2 Produc...
  • Min. Order: 10000
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  • China Zhuhaishi Shuangbojie Technology Co.,Ltd. [Manufacturer]
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  • Address: NO.101,Guofang Road,Gongbei,Zhuhai zhuhai,GuangdongChina
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50-81-7 L(+)-Ascorbic acid

  • Product Name: L(+)-Ascorbic acid Synonyms: 3-Keto-L-gulofuranolactone;3-Oxo-L-gulofuranolactone;3-oxo-l-gulofuranolactone(enolform);Adenex;Allercorb;Antiscorbic vitamin;antiscorbicvitamin;Antiscorbutic vitamin CAS: 50-81-7 EINECS: 200-066-2 MF: C6H8O...
  • China Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd. [Manufacturer, Trading Company]
  • Tel: 86-731-22292056
  • Address: No. 388, Huangshan Rd, Tianyuan District, Zhuzhou City, Hunan Province, P.R.China. zhuzhou,HunanChina
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50-81-7 L(+)-Ascorbic acid

  • L(+)-Ascorbic acid Synonyms:3-Keto-L-gulofuranolactone;3-Oxo-L-gulofuranolactone;3-oxo-l-gulofuranolactone(enolform);Adenex;Allercorb;Antiscorbic vitamin;antiscorbicvitamin;Antiscorbutic vitamin CAS:50-81-7 MF:C6H8O6 MW:176.12 EINECS:200-066-2 Produc...
  • Min. Order: 100000
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  • China Hubei Yuancheng Saichuang Technology Co.,Ltd. [Manufacturer]
  • Tel: 86-27-50756228
  • Fax: 86-27-88048077
  • Address: Wuchang wuhan,HubeiChina
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50-81-7 Vitamin C

  • Vitamin C Name: L(+)-Ascorbic acid,L-Ascorbic acid,VC EINECS: 200-066-2 Molecular Formula: C6H8O6 CAS Registry Number: 50-81-7 HS Code: 29362700 Molecular Structure: This structure is also available as a 2d Mol file Chemical Properties Appearance: Wh...
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  • China Hubei Yuancheng Saichuang Technology Co.,Ltd [Manufacturer]
  • Tel: 86-027-50755973
  • Address: No.496,Zhongshan Road,Wuchang District wuhan,HubeiChina
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50-81-7 99% High Quality Vitamin C with Nurition Supplement CAS 50-81-7

  • 99% High Quality Vitamin C with Nurition Supplement CAS 50-81-7 Product Description L(+)-Ascorbic acid Synonyms: 3-Keto-L-gulofuranolactone; 3-Oxo-L-gulofuranolactone Mp: 190~192o C Cas: 50-81-7 EINECS: 200-066-2 MF: C6H8O6 MW: 176.12 Assay: 99% Char...
  • Min. Order: 5000
  • FOB Price: USD1 - 1 /
  • China Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd. [Trading Company]
  • Tel: 86-731-22292017
  • Fax: --
  • Address: No. 388, Huangshan Rd, Tianyuan District, Zhuzhou City, Hunan Province, P.R.China. zhuzhou,HunanChina
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50-81-7 Acerola Cherry Extract; Malpighia Glabra L-Vitamin C 17% 25% 50-81-7

  • Acerola Cherry Extract; Malpighia Glabra L-Vitamin C 17% 25% 50-81-7 Product Description Part Used: Fruit Molecular Formula: C6H8O6 Molecular Weight: 176.12 Specification: Vitamin C 17%, 25%. Acerola is a small tree that grows in dry areas of the Car...
  • Min. Order: 5000
  • FOB Price: USD1 - 1 /
  • China Zhuzhou Yuancheng Hezhong Technology Development Co., Ltd. [Trading Company]
  • Tel: 86-731-22292017
  • Fax: --
  • Address: No. 388, Huangshan Rd, Tianyuan District, Zhuzhou City, Hunan Province, P.R.China. zhuzhou,HunanChina
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50-81-7 Ascorbic Acid

  • China Chemrio International Limited [Manufacturer]
  • Tel: +86 574 2789 1268/ +86-139 5789 5864 (mobile)
  • Fax: +86 574 2789 1266
  • Address: Chemrio International Limited
    Room 611-612, Wante Business Center
    No.487 Yangmuqi Road,
    Hi-tech Park Ningbo, 315040,China null,nullChina
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50-81-7 L-(+)-Ascorbic acid

  • L-(+)-Ascorbic acidVitamin C, >99.5%
  • United States INDOFINE Chemical Co., Inc. [Manufacturer]
  • Tel: (908) 359-6778
  • Fax: (908) 359-1179
  • Address: 121 Stryker Lane
    Bldg 30, Suite 1
    Hillsborough, NJ 08844 null,nullUnited States
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50-81-7 Ascorbic acid

  • Ascorbic acid
  • United States Chem-Impex International, Inc. [Manufacturer]
  • Tel: 630 766 2112
  • Fax: 630 766 2218
  • Address: 935 Dillon Drive Wood Dale IL 60191 USA ,nullUnited States
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50-81-7 L(+)-Ascorbic acid

  • United States HBCChem, Inc. [Manufacturers]
  • Tel: +1-510-219-6317
  • Fax: +1-510-675-0318
  • Address: null Union City,CaliforniaUnited States
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References of (2R)-2-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one
Title: Ascorbic Acid
CAS Registry Number: 50-81-7
CAS Name: L-Ascorbic acid
Synonyms: vitamin C; 3-oxo-L-gulofuranolactone; L-threo-hex-2-enonic acid g-lactone; L-3-keto-threo-hexuronic acid lactone; L-xylo-ascorbic acid; antiscorbutic vitamin; cevitamic acid
Trademarks: Ascorbicap (Valeant); Ascorbin (Montavit); Ascorvit (Jenapharm); Cantan (Aventis); Cebion (Merck KGaA); Cecon (Abbott); Celaskon (Leciva); Celin (GSK); Cetebe (GSK); Cevalin (Lilly); Ce-Vi-Sol (BMS); Cevitan (Aventis); Cewin (Sanofi-Synthelabo); C-Vimin (AstraZeneca); Hicee (Takeda); Hybrin (Pfizer); Laroscorbine (Roche); Redoxon (Roche); Ribena (GSK); Vitacimin (Takeda); Vitacin (Towa Yakuhin); Vitascorbol (Aventis)
Molecular Formula: C6H8O6
Molecular Weight: 176.12
Percent Composition: C 40.92%, H 4.58%, O 54.51%
Literature References: Physiological antioxidant. Coenzyme for a number of hydroxylation reactions; required for collagen synthesis. Widely distributed in plants and animals. Most primates (including humans), guinea pigs, and some birds and fish cannot synthesize ascorbic acid. Inadequate intake results in deficiency syndromes such as scurvy. Dietary sources include citrus fruits, potatoes, peppers, broccoli, cabbage, and rose hips. First isolated from the adrenal cortex of ox and later from lemons and paprika (originally called hexuronic acid): A. Szent-Gy?rgyi, Biochem. J. 22, 1387 (1928); W. N. Haworth, A. Szent-Gy?rgyi, Nature 131, 24 (1933). Structure studies: R. W. Herbert et al., J. Chem. Soc. 1933, 1270. Synthesis: R. G. Ault et al., ibid. 1419; T. Reichstein et al., Helv. Chim. Acta 16, 561, 1019 (1933); 17, 311, 510 (1934). Review of discovery, structure and synthesis: E. L. Hirst, Fortschr. Chem. Org. Naturst. 2, 132-159 (1939). Crystal structure: J. Hvoself, Acta Chem. Scand. 18, 841 (1964). Review of syntheses: T. C. Crawford, S. A. Crawford, Adv. Carbohydr. Chem. 37, 79-155 (1980). HPLC determn in plasma: J. Lykkesfeldt et al., Anal. Biochem. 229, 329 (1995). Discussion of use in the treatment of the common cold: L. Pauling, Proc. Natl. Acad. Sci. USA 68, 2678 (1971); H. Hemil?, Scand. J. Infect. Dis. 26, 1 (1994). Clinical applications in immunology, lipid metabolism and cancer: Int. J. Vitam. Nutr. Res. 1982, Suppl. 23, 294 pp. Comprehensive description: I. A. Al-Meshal, M. M. A. Hassan, Anal. Profiles Drug Subs. 11, 45-78 (1982). Reviews: G. M. Jaffe in Kirk-Othmer Encyclopedia of Chemical Technology vol. 24 (John Wiley & Sons, New York, 3rd Ed., 1984) pp 8-40; "Vitamin C" in Vitamins, W. Friedrich, Ed. (Walter de Gruyter, Berlin, 1988) pp 929-1001. Review of pharmacology and clinical applications: M. Levine, N. Engl. J. Med. 314, 892-902 (1986); H. E. Sauberlich, Annu. Rev. Nutr. 14, 371-391 (1994).
Properties: Crystals (usually plates, sometimes needles, monoclinic system). Pleasant, sharp acidic taste. mp 190-192° (some dec). d 1.65. [a]D25 +20.5 to +21.5° (c = 1 in water); [a]D23 +48° (c = 1 in methanol). pH = 3 (5 mg/ml); pH = 2 (50 mg/ml); pK1 = 4.17; pK2 = 11.57. uv max at pH 2: 245 nm (E1%1cm 695); at pH 6.4: 265 nm (E1%1cm 940). Redox potential (first stage): E10 +0.166 V (pH 4). One gram dissolves in about 3 ml water, 30 ml alc, 50 ml abs alc, 100 ml glycerol, 20 ml propylene glycol. Soly in water: 80.0% at 100°; 40.0% at 45°. Insol in ether, chloroform, benzene, petr ether, oils, fats, fat solvents. Strong reducing agent. Stable to air when dry; aq solns are rapidly oxidized by air.
Melting point: mp 190-192° (some dec)
pKa: pK1 = 4.17; pK2 = 11.57
Optical Rotation: [a]D25 +20.5 to +21.5° (c = 1 in water); [a]D23 +48° (c = 1 in methanol)
Absorption maximum: uv max at pH 2: 245 nm (E1%1cm 695); at pH 6.4: 265 nm (E1%1cm 940)
Density: d 1.65
 
Derivative Type: Calcium hypophosphite
Synonyms: Asphocalcium
Trademarks: Calscorbat (Aerocid)
Molecular Formula: C6H9CaO8P
Molecular Weight: 280.18
Percent Composition: C 25.72%, H 3.24%, Ca 14.30%, O 45.68%, P 11.05%
 
Derivative Type: Calcium salt
CAS Registry Number: 5743-27-1
Synonyms: Calcium ascorbate
Molecular Formula: C12H14CaO12
Molecular Weight: 390.31
Percent Composition: C 36.93%, H 3.62%, Ca 10.27%, O 49.19%
Literature References: Prepn: Ruskin, Merrill, Science 105, 504 (1947).
Properties: Dihydrate, triclinic crystals, [a]D20 +95.6° (c = 2.4). Freely sol in water. Practically insol in methanol, ethanol.
Optical Rotation: [a]D20 +95.6° (c = 2.4)
 
Derivative Type: Sodium salt
CAS Registry Number: 134-03-2
Synonyms: Sodium ascorbate
Trademarks: Cenolate (Abbott); Xitix (Woelm)
Molecular Formula: C6H7NaO6
Molecular Weight: 198.11
Percent Composition: C 36.38%, H 3.56%, Na 11.60%, O 48.46%
Literature References: Prepn: Holland, US 2442005 (1948).
Properties: Minute crystals, dec 218°. [a]D20 +104.4°. Soly in water: 62 g/100 ml at 25°; 78 g/100 ml at 75°.
Optical Rotation: [a]D20 +104.4°
 
Use: As antimicrobial and antioxidant in foodstuffs.
Therap-Cat: Vitamin (antiscorbutic).
Therap-Cat-Vet: Vitamin (antiscorbutic).
Keywords: Vitamin/Vitamin Source; Vitamin C.