Home > Name List By other > (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16, 17-decahydrocyclopenta[a]phenanthrene-3,17-diol

CAS No 50-28-2 , (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,
17-decahydrocyclopenta[a]phenanthrene-3,17-diol

  • Name: (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,
    17-decahydrocyclopenta[a]phenanthrene-3,17-diol
  • Synonyms: Estrace;(8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,
    17-decahydrocyclopenta[a]phenanthrene-3,17-diol; Diogynets; Dihydrofolliculin; progynon;beta-Estradiol; 17beta-Estradiol; Aquadiol; Oestradiol; Aerodiol;
  • CAS Registry Number:
  • Transport: HAZARD
  • Melting Point: 173 ºC
  • Flash Point: 209.6°C
  • Boiling Point: 445.9°Cat760mmHg
  • Density: 1.17g/cm3
  • Refractive index: 1.599
  • Water Solubility: practically insoluble
  • Safety Statements: R45
  • Hazard Symbols: T: Toxic;
  • Flash Point: 209.6°C
  • EINECS: 200-023-8
  • Molecular Weight: 272.38196
  • InchiKey: VOXZDWNPVJITMN-ZBRFXRBCSA-N
  • InChI: InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-
    7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1
  • Risk Statements: S53;S45
  • Molecular Formula: C18H24O2
  • Molecular Structure:CAS No:50-28-2 (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,<br />17-decahydrocyclopenta[a]phenanthrene-3,17-diol
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50-28-2 Estradiol

  • Dehydroepiandrosterone Stanozolol Boldenone undecylenate Testosterone Testosterone enanthate Testosterone propionate Metandienone Oxymetholone Trenbolone trenbolone enanthate Trenbolone acetate Nandrolone Decanoate Testosterone cypionate Oxandrolone ...
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50-28-2 Estradiol

  • Quick Details ProName: Estradiol hot sales CasNo: 50-28-2 Molecular Formula: C18H24O2 Appearance: White powder Application: Pharmaceuticals DeliveryTime: Within 15 workdays after payment PackAge: according to the clients requirement Port: All Chinese...
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50-28-2 (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16, 17-decahydrocyclopenta[a]phenanthrene-3,17-diol

  • Function and use: It is a kind of estrogen, can promote and regulate the normal development of women's genitals and secondary. Can cause hyperplasia of mammary gland carcinoma development, but in larger doses, can inhibit pituitary prolactin release,...
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50-28-2 (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16, 17-decahydrocyclopenta[a]phenanthrene-3,17-diol

  • Estradiol CAS No.: 50-28-2 Estradiol Molecular Formula: C18H24O2 Estradiol Molecular Weight: 272.38 Estradiol Assay: 98.66% Estradiol Reference Standard: USP28 Estradiol Appearance: White or creamy white crystalline powder Description
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50-28-2 (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16, 17-decahydrocyclopenta[a]phenanthrene-3,17-diol

  • Estradiol CAS No.: 50-28-2 Estradiol Molecular Formula: C18H24O2 Estradiol Molecular Weight: 272.38 Estradiol Assay: 98.66% Estradiol Reference Standard: USP28 Estradiol Appearance: White or creamy white crystalline powder Description
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50-28-2 (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16, 17-decahydrocyclopenta[a]phenanthrene-3,17-diol

  • Estradiol CAS No.: 50-28-2 Estradiol Molecular Formula: C18H24O2 Estradiol Molecular Weight: 272.38 Estradiol Assay: 98.66% Estradiol Reference Standard: USP28 Estradiol Appearance: White or creamy white crystalline powder
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50-28-2 (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16, 17-decahydrocyclopenta[a]phenanthrene-3,17-diol

  • Estradiol CAS No.: 50-28-2 Estradiol Molecular Formula: C18H24O2 Estradiol Molecular Weight: 272.38 Estradiol Assay: 98.66% Estradiol Reference Standard: USP28 Estradiol Appearance: White or creamy white crystalline powder Description
  • China Hubei Yuancheng Saisi Technology Co., Ltd [Manufacturer, Trading Company, Distributor/Wholesaler]
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50-28-2 (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16, 17-decahydrocyclopenta[a]phenanthrene-3,17-diol

  • Estradiol CAS No.: 50-28-2 Estradiol Molecular Formula: C18H24O2 Estradiol Molecular Weight: 272.38 Estradiol Assay: 98.66% Estradiol Reference Standard: USP28 Estradiol Appearance: White or creamy white crystalline powder Description
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50-28-2 Assay 98% Female Estrogen Hormone Powder Estradiol Raw Steroids Powder Cas 50-28-2

  • Assay 98% Female Estrogen Hormone Powder Estradiol Raw Steroids Powder Cas 50-28-2 Product name: Estradiol,Dihydrofolliculin CAS No.: 50-28-2 Molecular Formula: C18H24O2 Molecular Weight: 272.38 Assay: 98.66% Reference Standard: USP28 Appearance: Whi...
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50-28-2 Estradiol

  • Estradiol(CAS No.: 50-28-2) Synonyms:Estradiol,powder,hormone,steroid,Estra-1,3,5(10)-triene-3,17-diol, (17b)-;Estra-1,3,5(10)-triene-3,17b-diol;Estrace;Estraderm Formula: C18H24O2 Molecular Weight: 272.39 EINECS: 200-023-8 Purity:99% Appearance: whi...
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References of (8R,9S,13S,14S,17S)-13-methyl-6,7,8,9,11,12,14,15,16,
17-decahydrocyclopenta[a]phenanthrene-3,17-diol
Title: Estradiol
CAS Registry Number: 50-28-2
CAS Name: (17b)-Estra-1,3,5(10)-triene-3,17-diol
Synonyms: b-estradiol; cis-estradiol; 3,17-epidihydroxyestratriene; dihydrofollicular hormone; dihydrofolliculin; dihydroxyestrin; dihydrotheelin
Trademarks: Climara (Berlex); Estrace (Warner-Chilcott); Estraderm (Novartis); Estradot (Novartis); Estring (Pharmacia & Upjohn); Estrofem (Novo Nordisk); Estrogel (Solvay); Evorel (Janssen-Cilag); Menostar (Berlex); Systen (Janssen-Cilag); Vivelle (Novartis); Vivelle-Dot (Novartis); Zumenon (Solvay)
Molecular Formula: C18H24O2
Molecular Weight: 272.38
Percent Composition: C 79.37%, H 8.88%, O 11.75%
Literature References: Potent mammalian estrogenic hormone produced by the ovary. Triggers the production of gonadotropins leading to ovulation. Isoln from follicular fluid of sow ovaries: D. W. MacCorquodale et al., J. Biol. Chem. 115, 435 (1936). Has also been isolated from urine of pregnant women and mares. Prepn from estrone: A. Butenandt, C. Georgens, Z. Physiol. Chem. 248, 129 (1937); F. Hildebrandt et al., US 2096744 (1938 to Schering); from cholesterol: H. H. Inhoffen, G. Zühlsdorff, Ber. 74, 1914 (1941). Total syntheses: U. Eder et al., Ber. 109, 2948 (1976); W. Oppolzer, D. A. Roberts, Helv. Chim. Acta 63, 1703 (1980). Pharmacology: R. W. Lievertz, Am. J. Obstet. Gynecol. 156, 1289 (1987). HPLC determn in plasma and urine: W. Slikker et al., J. Chromatogr. 224, 205 (1981). Pharmacokinetics: W. Kuhnz et al., Arzneim.-Forsch. 43, 966 (1993). Clinical evaluation in osteoporosis: J. W. W. Studd et al., Br. J. Obstet. Gynaecol. 101, 787 (1994). Comprehensive description: E. G. Salole, Anal. Profiles Drug Subs. 15, 283-318 (1986). Physiologic review: H. G. Burger, Int. J. Gynaecol. Obstet. 1989, Suppl. 1, 5-9. Review of clinical safety and efficacy in estrogen replacement therapy: A. Cheang et al., Drug Saf. 9, 365-379 (1993); H. L. Judd, J. Reprod. Med. 39, 343-352 (1994).
Properties: White crystalline powder. Prisms from 80% alc, stable in air, mp 173-179°. [a]D25 +76 to +83° (dioxane). uv max: 225, 280 nm. Precipitated by digitonin. Practically insol in water. Freely sol in alcohol; sol in acetone, dioxane, other organic solvents; solns of fixed alkali hydroxides; sparingly sol in vegetable oils. 1 mg = 10,000 international units.
Melting point: mp 173-179°
Optical Rotation: [a]D25 +76 to +83° (dioxane)
Absorption maximum: uv max: 225, 280 nm
 
Derivative Type: Hemihydrate
CAS Registry Number: 35380-71-3
Trademarks: Estroclim (Sigma-Tau); Menorest (Novartis); Vagifem (Novo Nordisk)
Molecular Formula: C18H24O2.?H2O
Molecular Weight: 281.39
Percent Composition: C 76.83%, H 8.96%, O 14.21%
 
Derivative Type: 3-Acetate
CAS Registry Number: 4245-41-4
Trademarks: Femring (Warner-Chilcott); Femtrace (Warner-Chilcott)
Molecular Formula: C20H26O3
Molecular Weight: 314.42
Percent Composition: C 76.40%, H 8.33%, O 15.27%
 
Derivative Type: 3-Benzoate
CAS Registry Number: 50-50-0
Synonyms: Estradiol benzoate
Trademarks: Agofollin (Biotika); Duralease (Merial); Ovahormon (Teikoku Zoki); Progynon B (Schering AG)
Molecular Formula: C25H28O3
Molecular Weight: 376.49
Percent Composition: C 79.75%, H 7.50%, O 12.75%
Properties: Crystals from alc, mp 191-196°. Stable in air. [a]D25 +58 to +63° (c = 2 in dioxane). Sol in alc, acetone, dioxane; slightly sol in ether, vegetable oils.
Melting point: mp 191-196°
Optical Rotation: [a]D25 +58 to +63° (c = 2 in dioxane)
 
Derivative Type: 17b-Cyclopentanepropanoate
CAS Registry Number: 313-06-4
Synonyms: Estradiol cypionate; ECP
Molecular Formula: C26H36O3
Molecular Weight: 396.56
Percent Composition: C 78.75%, H 9.15%, O 12.10%
Literature References: Prepn: Ott, US 2611773 (1952 to Upjohn).
Properties: Crystals from benzene + petr ether, mp 151-152°. [a]D25 +45° (chloroform). Sol in ether, methanol, benzene, chloroform, peanut oil, cottonseed oil, corn oil, sesame oil.
Melting point: mp 151-152°
Optical Rotation: [a]D25 +45° (chloroform)
 
Derivative Type: Dipropionate
CAS Registry Number: 113-38-2
Trademarks: Ovahormon Depot (Teikoku)
Molecular Formula: C24H32O4
Molecular Weight: 384.51
Percent Composition: C 74.97%, H 8.39%, O 16.64%
Literature References: Prepn: K. Miescher, C. Scholz, US 2205627 (1940 to Ciba).
Properties: mp 104-105°.
Melting point: mp 104-105°
 
Derivative Type: 17-Heptanoate
CAS Registry Number: 4956-37-0
Synonyms: Estradiol enanthate
Manufacturers' Codes: SQ-16150
Molecular Formula: C25H36O3
Molecular Weight: 384.55
Percent Composition: C 78.08%, H 9.44%, O 12.48%
Literature References: Prepn: Gauthier et al., Ann. Pharm. Fr. 16, 757 (1958).
Properties: Crystals from diisopropyl ether, mp 94-96°.
Melting point: mp 94-96°
 
Derivative Type: 17-Valerate
CAS Registry Number: 979-32-8
Trademarks: Climaval (Novartis); Delestrogen (Monarch); Pelanin Depot (Mochida); Progynon Depot (Schering AG); Progynova (Schering AG)
Molecular Formula: C23H32O3
Molecular Weight: 356.50
Percent Composition: C 77.49%, H 9.05%, O 13.46%
Literature References: Prepn: K. Miescher, C. Scholz, US 2233025 (1941 to Ciba). Comprehensive description: K. Florey, Anal. Profiles Drug Subs. 4, 192-208 (1975).
Properties: Crystals, mp 144-145°.
Melting point: mp 144-145°
 
CAUTION: These substances are listed as known human carcinogens: Report on Carcinogens, Eleventh Edition (PB2005-104914, 2004) p III-115.
Therap-Cat: Estrogen.
Therap-Cat-Vet: Estrogen.
Keywords: Estrogen; Steroidal.