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CAS No 49843-98-3 , 1H-Carbazole-1-carboxamide,6-chloro-2,3,4,9-tetrahydro-

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49843-98-3 EX-527(Selisistat)

  • EX-527 is a novel, potent, and specific small-molecule inhibitor of SIRT1 catalytic activity to examine the role of SIRT1 in p53 acetylation and cell survival after DNA damage. Treatment with EX-527 dramatically increased acetylation at lysine 382 of...
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