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CAS No 4940-39-0 , 4-oxochromene-2-carboxylic acid

  • Name: 4-oxochromene-2-carboxylic acid
  • Synonyms: Atremon; 4-Oxo-4H-1-benzopyran-2-carboxylic acid;chromocarb; Chromone-2-carboxylic acid;4-oxochromene-2-carboxylic acid; 4940-39-0; 4-Oxo-4H-chromene-2-carboxylic acid;
  • CAS Registry Number:
  • Melting Point: 260 ºC
  • Density: 1.493 g/cm3
  • Safety Statements: R36/37/38
  • Hazard Symbols: Xi: Irritant;
  • EINECS: 225-583-0
  • Molecular Weight: 190.15224
  • InchiKey: RVMGXWBCQGAWBR-UHFFFAOYSA-N
  • InChI: InChI=1S/C10H6O4/c11-7-5-9(10(12)13)14-8-4-2-1-3-6(7)8/h1-5H,(H,12,13)
  • Risk Statements: S26;S37/39
  • Molecular Formula: C10H6O4
  • Molecular Structure:CAS No:4940-39-0 4-oxochromene-2-carboxylic acid
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4940-39-0 CHROMONE-2-CARBOXYLIC ACID; 97%

  • Germany ABCR GmbH & Co KG [Manufacturer]
  • Tel: +49 721 95061-0
  • Fax: +49 721 95061-80
  • Address: Im Schlehert 10
    76187 Karlsruhe
    Germany null,nullGermany
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4940-39-0 CHROMONE-2-CARBOXYLIC ACID, 97%

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong null,nullHong kong
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4940-39-0 Chromone-2-carboxylic acid

  • China Chemrio International Limited [Manufacturer]
  • Tel: +86 574 2789 1268/ +86-139 5789 5864 (mobile)
  • Fax: +86 574 2789 1266
  • Address: Chemrio International Limited
    Room 611-612, Wante Business Center
    No.487 Yangmuqi Road,
    Hi-tech Park Ningbo, 315040,China null,nullChina
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4940-39-0 Chromone-2-carboxylic acid

  • China Hangzhou Sage Chemical Co., Ltd. [Manufacturer]
  • Tel: +86-571-86818502
  • Fax: +86-571-86818503
  • Address: RM501 Tower A, New Youth Plaza, NO.8 Jia Shan Road, Hangzhou, Zhejiang 310014, null,ZhejiangChina
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4940-39-0 Chromone-2-carboxylic acid

  • China Shanghai Xunxin Chemical Co., Ltd [Manufacturers]
  • Tel: +86-(21)-38218795
  • Fax: +86-(21)-38218795
  • Address: 580 Lane, Kanghong Road, Pudong New District, Shanghai 201315, Shanghai,ShanghaiChina
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4940-39-0 Chromone-2-carboxylic acid

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4940-39-0 Chromone-2-carboxylic acid

  • China China Langchem Inc. null
  • Tel: +86-(21)-58956006
  • Fax: +86-(21)-58956100
  • Address: 514 Room, 1# Building, 88# Cailun Road, Zhangjiang High Tech Park, Shanghai 201203, null,nullChina
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4940-39-0 CHROMOCARB

  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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4940-39-0 CHROMONE-2-CARBOXYLIC ACID

  • United States Carbocore, Inc. [Manufacturer]
  • Tel: 281-367-6833
  • Fax: 281-419-4974
  • Address: Carbocore, Inc.
    P.O. Box 131508
    The Woodlands, TX
    77393-1508 USA null,nullUnited States
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4940-39-0 4-Oxo-4H-1-benzopyran-2-carboxylic acid

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References of 4-oxochromene-2-carboxylic acid
Title: Chromocarb
CAS Registry Number: 4940-39-0
CAS Name: 4-Oxo-4H-1-benzopyran-2-carboxylic acid
Synonyms: 2-chromonecarboxylic acid; 4-oxo-4H-chromene-2-carboxylic acid; benzo-g-pyronecarboxylic acid
Molecular Formula: C10H6O4
Molecular Weight: 190.15
Percent Composition: C 63.16%, H 3.18%, O 33.66%
Literature References: Prepn: S. Ruhemann, H. E. Stapleton, J. Chem. Soc. 77, 1179 (1900); J. Schmutz et al., Helv. Chim. Acta 34, 767 (1951); G. Pifferi et al., J. Heterocycl. Chem. 14, 1257 (1977). Prepn of diethylamine salt: P. A. Tronche, ZA 6807352; eidem, US 3816470 (1969, 1974 both to Ferlux). Pharmacology of diethylamine salt in animals: J. Couquelet et al., C.R. Seances Soc. Biol. Ses Fil. 164, 329 (1970); P. Conquet et al., ibid. 800. Clinical comparison with dipyridamole of effect on platelet function: A. Vittoria et al., Curr. Ther. Res. 35, 1033 (1984). Clinical trial in diabetes with vascular disease: N. Ciavarella et al., ibid. 36, 293 (1984). Bioavailability in humans: J.-M. Aiache et al., Biopharm. Drug Dispos. 7, 301 (1986).
Properties: Colorless needles from alcohol, mp 250-251° (dec) (Ruhemann, Stapleton); also reported as mp 255-256° (Pifferi). uv max: 230, 305 nm (e 20220, 8075). Sol in alcohol, ammonia. Sparingly sol in water.
Melting point: mp 250-251° (dec) (Ruhemann, Stapleton); mp 255-256° (Pifferi)
Absorption maximum: uv max: 230, 305 nm (e 20220, 8075)
 
Derivative Type: Diethylamine
CAS Registry Number: 23915-80-2
Trademarks: Angiophtal (Merck & Co.); Campel (Farmitalia); Fludarene (Merck & Co.)
Molecular Formula: C14H17NO4
Molecular Weight: 263.29
Percent Composition: C 63.86%, H 6.51%, N 5.32%, O 24.31%
Properties: Microcrystalline powder from alcohol + acetone, mp 138°. Sol in water. LD50 in mice: ~800 mg/kg i.v.; >5 g/kg orally (Tronche, 1974).
Melting point: mp 138°
Toxicity data: LD50 in mice: ~800 mg/kg i.v.; >5 g/kg orally (Tronche, 1974)
 
Therap-Cat: Diethylamine salt as capillary protectant.
Keywords: Vasoprotectant.