Title: Fructose-1,6-diphosphate
CAS Registry Number: 488-69-7
CAS Name: D-Fructose 1,6-bis(dihydrogen phosphate)
Synonyms: 1,6-D-fructosediphosphoric acid; hexose diphosphate; Harden-Young ester
Molecular Formula: C6H14O12P2
Molecular Weight: 340.12
Percent Composition: C 21.19%, H 4.15%, O 56.45%, P 18.21%
Literature References: Formed from fructose-6-phosphate in the presence of ATP, Mg2+ and the enzyme phosphohexokinase. Prepn from glucose, mannose, fructose, sucrose by the action of yeasts: A. Harden,
Alcoholic Fermentation (Longmans, Green & Co., New York, 4th ed., 1932); v. Lebedev,
Biochem. Z. 36, 254 (1911);
cf DE 292817;
DE 293864;
DE 301590. Fructose-1,6-diphosphate is reversibly split in the presence of aldolase forming 1-phosphodihydroxyacetone and 3-phosphoglyceraldehyde: Meyerhof
et al., Biochem. Z. 286, 301 (1936). Metabolism regulation study: M. E. Kirtley, M. McKay,
Mol. Cell. Biochem. 18, 141 (1977).
Derivative Type: Sodium salt monohydrate
Trademarks: Esafosfina (Foscama)
Therap-Cat: Roborant; tonic.