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CAS No 484-20-8 , 4-methoxyfuro[3,2-g]chromen-7-one

  • Name: 4-methoxyfuro[3,2-g]chromen-7-one
  • Synonyms: 484-20-8; Psoraderm; BERGAPTAN; 5-Methoxypsoralen;4-methoxyfuro[3,2-g]chromen-7-one; Majudin; 5-Methoxyfuranocoumarin; Heraclin; bergaptene;Bergapten;
  • CAS Registry Number:
  • Transport: UN 1759
  • Melting Point: 190-193 ºC
  • Density: 1.368 g/cm3
  • Refractive index: 1.635
  • Water Solubility: negligible in water
  • Safety Statements: R43
  • Hazard Symbols: Xi: Irritant;
  • EINECS: 207-604-5
  • Molecular Weight: 216.18952
  • InchiKey: BGEBZHIAGXMEMV-UHFFFAOYSA-N
  • InChI: InChI=1S/C12H8O4/c1-14-12-7-2-3-11(13)16-10(7)6-9-8(12)4-5-15-9/h2-6H,
    1H3
  • Risk Statements: S36/37
  • Molecular Formula: C12H8O4
  • Molecular Structure:CAS No:484-20-8 4-methoxyfuro[3,2-g]chromen-7-one

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484-20-8 5-METHOXYPSORALEN

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
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484-20-8 BERGAPTEN

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484-20-8 Bergapten

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484-20-8 7H-Furo[3,2-g][1]benzopyran-7-one,4-methoxy-

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484-20-8 BERGAPTEN

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References of 4-methoxyfuro[3,2-g]chromen-7-one
Title: Bergapten
CAS Registry Number: 484-20-8
CAS Name: 4-Methoxy-7H-furo[3,2-g][1]benzopyran-7-one
Synonyms: 5-methoxypsoralen; bergaptan; bergaptene; heraclin; majudin; 5-MOP
Trademarks: Psoraderm-5 (Sunlife)
Molecular Formula: C12H8O4
Molecular Weight: 216.19
Percent Composition: C 66.67%, H 3.73%, O 29.60%
Literature References: Naturally occurring analog of psoralen and isomer of methoxsalen, q.q.v., found in a wide variety of plants. It was first isolated from oil of bergamot from Citrus bergamia Risso, Aurantiodiae: Pomeranz, Monatsh. Chem. 12, 379 (1891), 14, 28 (1893). Isoln from Fagara xanthoxyloides Lam., Rutaceae: H. Thoms, E. Baetcke, Ber. 44, 3326 (1911); 45, 3705 (1912). Synthesis: E. Sp?th et al., Ber. 70, 478 (1937); W. N. Howell, R. Robertson, J. Chem. Soc. 1937, 293; G. Caporale, Farmaco Ed. Sci. 13, 784 (1958); V. K. Ahluwalia et al., Indian J. Chem. 7, 831 (1969). Use in photochemotherapy of psoriasis: H. H?nigsmann et al., Br. J. Dermatol. 101, 369 (1979). Mutagenicity studies: B. R. Scott et al., Mutat. Res. 39, 29 (1976); M. J. Ashwood-Smith et al., Nature 285, 407 (1980). Phototoxicity study: A. Kornhauser et al., Science 217, 733 (1982).
Properties: Needles from alcohol, mp 188° (sublimes). Practically insol in boiling water. Slightly sol in glacial acetic acid, chloroform, benzene, warm phenol. Sol in abs alcohol: 1 part in 60. Its soln in sulfuric acid is yellow-gold.
Melting point: mp 188° (sublimes)
Use: Has been used to promote tanning in suntan preparations.
Therap-Cat: Antipsoriatic.
Keywords: Antipsoriatic.