Home > Name List By n > N,N-dimethyl-1-pyrido[3,2-b][1,4]benzothiazin-10-ylpropan-2-amine

CAS No 482-15-5 , N,N-dimethyl-1-pyrido[3,2-b][1,4]benzothiazin-10-ylpropan-2-amine

  • Name: N,N-dimethyl-1-pyrido[3,2-b][1,4]benzothiazin-10-ylpropan-2-amine
  • Synonyms: Actapront;Andanton; Isothipendylum [INN-Latin]; Nilergex;N,N-dimethyl-1-pyrido[3,2-b][1,4]benzothiazin-10-ylpropan-2-amine; Isothipendylum; Odantol; Isothipendyl [INN:BAN]; Udantol;
  • CAS Registry Number:
  • Flash Point: 208.6°C
  • Boiling Point: 421.3°Cat760mmHg
  • Density: 1.167g/cm3
  • Refractive index: 1.62
  • Safety Statements: A poison by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic vapors of NOx and SOx.
  • Flash Point: 208.6°C
  • EINECS: 207-578-5
  • Molecular Weight: 285.40716
  • InchiKey: OQJBSDFFQWMKBQ-UHFFFAOYSA-N
  • InChI: InChI=1S/C16H19N3S/c1-12(18(2)3)11-19-13-7-4-5-8-14(13)20-15-9-6-10-17-
    16(15)19/h4-10,12H,11H2,1-3H3
  • Molecular Formula: C16H19N3S
  • Molecular Structure:CAS No:482-15-5 N,N-dimethyl-1-pyrido[3,2-b][1,4]benzothiazin-10-ylpropan-2-amine

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References of N,N-dimethyl-1-pyrido[3,2-b][1,4]benzothiazin-10-ylpropan-2-amine
Title: Isothipendyl
CAS Registry Number: 482-15-5
CAS Name: N,N,a-Trimethyl-10H-pyrido[3,2-b][1,4]benzothiazine-10-ethanamine
Synonyms: 10-(2-dimethylamino-2-methylethyl)-10H-pyrido[3,2-b][1,4]benzothiazine; 10-(2-dimethylaminopropyl)-1-azaphenothiazine; N-dimethylaminoisopropylthiophenylpyridylamine
Manufacturers' Codes: D-201
Molecular Formula: C16H19N3S
Molecular Weight: 285.41
Percent Composition: C 67.33%, H 6.71%, N 14.72%, S 11.23%
Literature References: Prepn: H. L. Yale, F. Sowinski, J. Am. Chem. Soc. 80, 1651 (1958). Pharmacology: A. von Schlichtegroll, Arzneim.-Forsch. 8, 489 (1958). Clinical evaluation: N. W. Klehr et al., Therapiewoche 34, 6050 (1984); E. Milsmann, P. Rohdewald, Dermatologica 170, 230 (1985). Spectroscopic determn: M. H. Abdel-Hay et al., J. Pharm. Belg. 45, 259 (1990). HPLC determn: A. Turcant et al., Clin. Chem. 37, 1210 (1991).
Properties: bp0.4mm 171-174°. LD50 in mice (mg/kg): 65 ±2 i.p.; 222 ±18 orally (Schlichtegroll).
Boiling point: bp0.4mm 171-174°
Toxicity data: LD50 in mice (mg/kg): 65 ±2 i.p.; 222 ±18 orally (Schlichtegroll)
 
Derivative Type: Hydrochloride
CAS Registry Number: 1225-60-1
Trademarks: Andantol (Sumitomo); Andanton (Lacer); Nilergex
Molecular Formula: C16H19N3S.HCl
Molecular Weight: 321.87
Percent Composition: C 59.70%, H 6.26%, N 13.05%, S 9.96%, Cl 11.01%
Properties: Sol in water.
 
Therap-Cat: Antihistaminic.
Keywords: Antihistaminic; Tricyclics; Other Tricyclics.