Title: Cepharanthine
CAS Registry Number: 481-49-2
CAS Name: 6¢,12¢-Dimethoxy-2,2¢-dimethyl-6,7-[methylenebis(oxy)]oxyacanthan
Molecular Formula: C37H38N2O6
Molecular Weight: 606.71
Percent Composition: C 73.25%, H 6.31%, N 4.62%, O 15.82%
Literature References: From tubers of
Stephania cephalantha Hayata, and
Stephania sasahii Hayata,
Menispermaceae: Kondo
et al., US 2206407 (1940); Kondo, Hasegawa,
US 2248241 (1941). Structure: Kondo, Keimatsu,
Ber. 71, 2553 (1938); Tomita, Sasaki,
Pharm. Bull. 2, 89, 375 (1954). Total synthesis (
dl-form): Tomita
et al., Tetrahedron Lett. 1967, 1201.
Properties: Yellow powder, mp 145-155°. Obtained by drying solvated needles from acetone + benzene. [a]D20 +277° (c = 2 in chloroform). Soluble in the usual organic solvents except petr ether.
Melting point: mp 145-155°
Optical Rotation: [a]D20 +277° (c = 2 in chloroform)