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CAS No 481-49-2 , Cepharanthine

  • Name: Cepharanthine
  • Synonyms: Cepharanthine (JAN); 481-49-2;Cepharanthin; NSC623442; O-Methylcepharanoline;Cepharanthine; CCRIS 6539; Cepharantin; (+)-Cepharanthine;
  • CAS Registry Number:
  • Melting Point: 140 - 145
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: 1.227 g/cm3
  • Refractive index: 1.608
  • Safety Statements: Poison by subcutaneous, intravenous, and intraperitoneal routes. Moderately toxic by ingestion. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx.
  • Flash Point: °C
  • Molecular Weight: 606.70742
  • InchiKey: YVPXVXANRNDGTA-WDYNHAJCSA-N
  • InChI: InChI=1S/C37H38N2O6/c1-38-13-11-24-18-31(41-4)33-20-27(24)28(38)16-23-7-
    10-30(40-3)32(17-23)44-26-8-5-22(6-9-26)15-29-35-25(12-14-39(29)2)19-34-
    36(37(35)45-33)43-21-42-34/h5-10,17-20,28-29H,11-16,21H2,1-4H3/t28-,
    29+/m1/s1
  • Molecular Formula: C37H38N2O6
  • Molecular Structure:CAS No:481-49-2 Cepharanthine

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481-49-2 1H-4,6:16,19-Dietheno-21,25-metheno-12H-[1,3]dioxolo[4,5-g]pyrido[2',3':17,18][1,10]dioxacycloeicosino[2,3,4-ij]isoquinoline,2,3,13,14,14a,15,26,26a-octahydro-22,30-dimethoxy-1,14-dimethyl-, (14aS,26aR)-

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References of Cepharanthine
Title: Cepharanthine
CAS Registry Number: 481-49-2
CAS Name: 6￠,12￠-Dimethoxy-2,2￠-dimethyl-6,7-[methylenebis(oxy)]oxyacanthan
Molecular Formula: C37H38N2O6
Molecular Weight: 606.71
Percent Composition: C 73.25%, H 6.31%, N 4.62%, O 15.82%
Literature References: From tubers of Stephania cephalantha Hayata, and Stephania sasahii Hayata, Menispermaceae: Kondo et al., US 2206407 (1940); Kondo, Hasegawa, US 2248241 (1941). Structure: Kondo, Keimatsu, Ber. 71, 2553 (1938); Tomita, Sasaki, Pharm. Bull. 2, 89, 375 (1954). Total synthesis (dl-form): Tomita et al., Tetrahedron Lett. 1967, 1201.
Properties: Yellow powder, mp 145-155°. Obtained by drying solvated needles from acetone + benzene. [a]D20 +277° (c = 2 in chloroform). Soluble in the usual organic solvents except petr ether.
Melting point: mp 145-155°
Optical Rotation: [a]D20 +277° (c = 2 in chloroform)