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CAS No 479-18-5 , 7-(2,3-dihydroxypropyl)-1,3-dimethylpurine-2,6-dione Search by region : China

  • Name: 7-(2,3-dihydroxypropyl)-1,3-dimethylpurine-2,6-dione
  • Synonyms: Neutrafillina; Neutraphyllin;Diprophylline;7-(2,3-dihydroxypropyl)-1,3-dimethylpurine-2,6-dione; Neutraphylline; Aristophyllin; Lufyllin; Glyphylline; Neostenovasan;
  • CAS Registry Number:
  • Melting Point: 160-165 ºC
  • Flash Point: 310.4°C
  • Boiling Point: 589.6°C at 760 mmHg
  • Density: 1.57g/cm3
  • Refractive index: 1.5403 (172 C)
  • Water Solubility: 33 G/100 ML (25 ºC)
  • Safety Statements: R22
  • Hazard Symbols: Xn: Harmful;
  • Flash Point: 310.4°C
  • EINECS: 207-526-1
  • Molecular Weight: 254.24256
  • InchiKey: KSCFJBIXMNOVSH-UHFFFAOYSA-N
  • InChI: InChI=1S/C10H14N4O4/c1-12-8-7(9(17)13(2)10(12)18)14(5-11-8)3-6(16)4-15/
    h5-6,15-16H,3-4H2,1-2H3
  • Risk Statements: R22
  • Molecular Formula: C10H14N4O4
  • Molecular Structure:CAS No:479-18-5 7-(2,3-dihydroxypropyl)-1,3-dimethylpurine-2,6-dione

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479-18-5 diprophylline

  • China Syntechem Co.,Ltd [Manufacturer]
  • Tel: +86-519-89882658
  • Fax: +86-519-8512 5369
  • Address: Syntechem Co.,Ltd
    18 South Zhulin Rd.
    Tianning district,Changzhou
    Jiangsu China 213022 null,nullChina
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479-18-5 diprophylline

  • China Taiyuan RHF CO., ltd. [Manufacturers]
  • Tel: 0351-7436719
  • Fax: +86-351-7436719
  • Address: Shuangta South Alley 46,2-1, YingZe Area,Taiyuan, ShanXi null,ShanXiChina
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479-18-5 diprophylline

  • China Xilin Chemical Group Co., Ltd null
  • Tel: +86-(0)-15527136576
  • Fax: +86-(27)-83820093
  • Address: 16# Luojiashan, Wuchang District, Wuhan, Hubei 430071, null,nullChina
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479-18-5 diprophylline

  • China YiPeng Chemical [Manufacturers]
  • Tel: 571 85376369
  • Fax: 571 88233092
  • Address: Building 4,High-tech Industrial Park,No. 588 Feijiatang Road,Xiacheng District, Hangzhou, China null,ZheJiangChina
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479-18-5 Diprophylline

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479-18-5 Dyphylline

  • China Watson International Ltd. null
  • Tel: +86-(512)-55117610
  • Fax: +86-(512)-55117630
  • Address: Room 1209, Asia Pacific Plaza, Huaqiao International Business Park, Kunshan, Jiangsu 215332, null,nullChina
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479-18-5 diprophylline

  • China Hangzhou Starshine Pharmaceutical Co., LTD [Manufacturers]
  • Tel: +86-571-89939756 85122191
  • Fax: +86-571-85122157
  • Address: ROOM A, 20 TH FLOOR, WEST BUILDING, INTERNATIONAL GARDEN, NO.160 TIANMUSHAN ROAD, HANGZHOU, CHINA null,ZhejiangChina
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479-18-5 Diprophylline

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479-18-5 Dyphylline

  • China Edengene Chemical Limited [Manufacturers]
  • Tel: +86-(519)-85208709
  • Fax: +86-(519)-85130733
  • Address: 1402, Aite Building, 238-2, Tongjiang Nan Road, Changzhou, Jiangsu, Changzhou,JiangsuChina
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479-18-5 Diprophylline

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References of 7-(2,3-dihydroxypropyl)-1,3-dimethylpurine-2,6-dione
Title: Dyphylline
CAS Registry Number: 479-18-5
CAS Name: 7-(2,3-Dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
Synonyms: 7-(2,3-dihydroxypropyl)theophylline; (1,2-dihydroxy-3-propyl)theophylline; glyphylline; glyfyllin; diprophylline; AFI-phyllin
Trademarks: Astmamasit (Showa Yakuhin); Asthmolysin (Kade); Astrophyllin; Circair (Circle); Coronarin; Cor-Theophyllin (Paramedical); Dilor (Savage); Hiphyllin; Hyphylline; Lufyllin (Mallinckrodt); Neostenovasan; Neothylline (Lemmon); Neotilina; Neo-Vasophylline; Neutrafil; Neutraphylline (Dorsey); Prophyllen (Streuli); Silbephylline (Berk); Solufilin; Solufyllin; Theal ampules (Boehringer, Mann.); Thefylan
Molecular Formula: C10H14N4O4
Molecular Weight: 254.24
Percent Composition: C 47.24%, H 5.55%, N 22.04%, O 25.17%
Literature References: Prepn: Jones, Maney, US 2575344 (1951 to State Univ. of Iowa); Roth, Arch. Pharm. 292, 234 (1959). Toxicity data: R. A. Al'tshuler, Med. Prom. SSSR 16, 57 (1962), C.A. 61, 6230g (1964).
Properties: Extremely bitter crystals from alcohol, mp 158°. uv max (0.001% in H2O): 273 nm (A1%1cm 361). Freely sol in water; one gram dissolves in 3 ml H2O at 25°. Soly (g/100 ml): alc 2; chloroform 1. pH (1% aq soln) 6.6 to 7.3. LD50 in mice (mg/kg): 3400 orally; 1430 s.c. (Al'tshuler).
Melting point: mp 158°
Absorption maximum: uv max (0.001% in H2O): 273 nm (A1%1cm 361)
Toxicity data: LD50 in mice (mg/kg): 3400 orally; 1430 s.c. (Al'tshuler)
Therap-Cat: Bronchodilator.
Keywords: Bronchodilator; Xanthine Derivatives.