Home > Name List By other > (2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-hydroxy-2,4a,6a,6b,9,9, 12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12, 14b-dode...

CAS No 471-53-4 , (2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-hydroxy-2,4a,6a,6b,9,9,
12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,
14b-dodecahydro-1H-picene-2-carboxylic acid

  • Name: (2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-hydroxy-2,4a,6a,6b,9,9,
    12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,
    14b-dodecahydro-1H-picene-2-carboxylic acid
  • Synonyms: 471-53-4; GLYCYRRHETINIC ACID;enoxolone;(2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-hydroxy-2,4a,6a,6b,9,9,
    12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,
    14b-dodecahydro-1H-picene-2-carboxylic acid; Arthrodont; 18beta-Glycyrrhetinic acid; Rhetinic Acid; Jintan; Uralenic acid; Glycyrrhetic acid;
  • CAS Registry Number:
  • Transport: HAZARD
  • Melting Point: 292-295 ºC
  • Flash Point: 323.7°C
  • Boiling Point: 588.3°Cat760mmHg
  • Density: 1.14g/cm3
  • Refractive index: 162 ° (C=1, MeOH)
  • Alpha: 165 º (C=1, CHCL3,ON DRY BA)
  • Safety Statements: R22;R36
  • Hazard Symbols: Xn: Harmful;
  • Flash Point: 323.7°C
  • EINECS: 207-444-6
  • Molecular Weight: 470.68384
  • InchiKey: MPDGHEJMBKOTSU-YKLVYJNSSA-N
  • InChI: InChI=1S/C30H46O4/c1-25(2)21-8-11-30(7)23(28(21,
    5)10-9-22(25)32)20(31)16-18-19-17-27(4,24(33)34)13-12-26(19,
    3)14-15-29(18,30)6/h16,19,21-23,32H,8-15,17H2,1-7H3,(H,33,34)/t19-,21-,
    22-,23+,26+,27-,28-,29+,30+/m0/s1
  • Risk Statements: S22;S24/25
  • Molecular Formula: C30H46O4
  • Molecular Structure:CAS No:471-53-4 (2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-hydroxy-2,4a,6a,6b,9,9,<br />12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,<br />14b-dodecahydro-1H-picene-2-carboxylic acid

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471-53-4 Glycyrrhetinic acid

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471-53-4 GLYCYRRHETINIC ACID

  • United States DeWolf Chemical, Inc. [Manufacturer]
  • Tel: 800-521-0065/ 401-434-3515
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  • Address: DeWolf Chemical, Inc.
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471-53-4 Enoxolone

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471-53-4 Enoxolone

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471-53-4 Glycyrrhetinic acid

  • Glycyrrhetinic acid, 97%
  • China glycyrrhiza@fanzhigroup.com [Manufacturer]
  • Tel: 0086 931 8559501
  • Fax: 0086 931 8559500
  • Address: 9F., Block A?Entrepreneur Building , Innovation Park, No.268,South Side Beach, Lanzhou, China 730010 LANZHOUCHINA LANZHOU,nullChina
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471-53-4 18-BETA-GLYCYRRHETIC ACID (ENOXOLONE)

  • China VITAL-CHEM ZHUHAI CO., LTD [Manufacturer]
  • Tel: 86-756-3337592/ 86-756-3374435
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  • Address: 2B/F,BLOCK 3 NO.169 SHIHUA WEST ROAD,
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471-53-4 Enoxolone

  • China Fanzhi Pharmacy [Manufacturers]
  • Tel: 86 931 8553009, 8559501
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  • Address: No.268,Nanmiantan,Lanzhou,China Lanzhou,GansuChina
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471-53-4 Enoxolone

  • China Fanzhi Pharmacy Co., Ltd. [Manufacturers]
  • Tel: 86-931-8559501/8559502
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  • Address: 9F/.,A, Entrepreneur Building,268 NanMiantan,Lanzhou, China 730010 Nanmiantan,LanzhouChina
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471-53-4 18-alpha-Glycyrrhetinic acid

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471-53-4 Glycyrrhetic acid

  • Glycyrrhetic acid
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
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  • Address: CHEMOS GmbH
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References of (2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-hydroxy-2,4a,6a,6b,9,9,
12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,
14b-dodecahydro-1H-picene-2-carboxylic acid
Title: Enoxolone
CAS Registry Number: 471-53-4
CAS Name: (3b,20b)-3-Hydroxy-11-oxoolean-12-en-29-oic acid
Synonyms: 3b-hydroxy-11-oxoolean-12-en-30-oic acid; glycyrrhetic acid; 18b-glycyrrhetinic acid; uralenic acid
Trademarks: Arthrodont (Veyron-Froment); Biosone (Berk); P.O. 12 (Bioth?ax)
Molecular Formula: C30H46O4
Molecular Weight: 470.68
Percent Composition: C 76.55%, H 9.85%, O 13.60%
Literature References: From glycyrrhizic acid, q.v. Structure: Ruzicka et al., Helv. Chim. Acta 26, 2143, 2278 (1943). Stereochemistry: Beaton, Spring, J. Chem. Soc. 1955, 3126. Prepn from shredded licorice root: Mer, Am. Perfum. Aromat. 74(6), 39 (1959). Manuf: GB 833184 (1960 to Carlo Erba). Identity with uralenic acid: Belous et al., Zh. Obshch. Khim. 35, 401 (1965). Metabolism: Parke et al., J. Pharm. Pharmacol. 15, 500 (1963). Mechanism of action: Helbing, Berntsen, Pharm. Weekbl. 100, 1438 (1965).
Properties: Needles from alcohol + petr ether, mp 296°. [a]D21 +86° (alc); [a]D20 +145.5° (dioxane); [a]D20 +163° (chloroform). Freely sol in chloroform, dioxane. Soluble in alcohol, pyridine, acetic acid. Practically insol in petr ether.
Melting point: mp 296°
Optical Rotation: [a]D21 +86° (alc); [a]D20 +145.5° (dioxane); [a]D20 +163° (chloroform)
 
Derivative Type: 18a-Hydrogen Form
Properties: Platelets from dil alcohol, mp 335°. [a]D20 +140° (alcohol); [a]D +98° (c = 0.1 in chloroform). Sol in alcohol, dioxane, chloroform.
Melting point: mp 335°
Optical Rotation: [a]D20 +140° (alcohol); [a]D +98° (c = 0.1 in chloroform)
 
Therap-Cat: Anti-inflammatory (topical).
Keywords: Glucocorticoid.