References of (1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione
Title: Curcumin
CAS Registry Number: 458-37-7
CAS Name: (1
E,6
E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione
Synonyms: turmeric yellow; diferuloylmethane; C.I. 75300; C.I. Natural Yellow 3
Molecular Formula: C21H20O6
Molecular Weight: 368.38
Percent Composition: C 68.47%, H 5.47%, O 26.06%
Literature References: Natural dyestuff from root of
Curcuma longa L.,
Zingiberaceae. Isoln: Vogel,
Ann. 44, 297 (1842); Perkin, Phipps,
J. Chem. Soc. (Trans.)
85, I, 64 (1904); Rao, Shintre,
J. Soc. Chem. Ind. 47, 54T (1928). Synthesis: Lampe,
Ber. 51, 1347 (1918). Production: Stieglitz, Horn,
DE 859145 (1952 to Hoechst). Biosynthesis studies: Roughley, Whiting,
Tetrahedron Lett. 1971, 3741. Chromatography: Srinivasan,
J. Pharm. Pharmacol. 5, 448 (1953).
See also: H. J. Conn's Biological Stains, R. D. Lillie, Ed. (Williams & Wilkins, Baltimore, 9th ed., 1977) pp 474-476. Pharmacology and anti-inflammatory activity: Srimal, Dhawan,
ibid. 25, 447 (1973).
Properties: Orange-yellow, cryst powder, mp 183°. Insol in water, ether. Sol in alcohol, glacial acetic acid. Gives a brownish-red color with alkali; a light-yellow color with acids.
Melting point: mp 183°
Use: For preparing curcuma paper, pH range 8-9. In the detection of boron.
