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CAS No 438-60-8 , 3-(11H-dibenzo[1,2-a:1',2'-e][7]annulen-11-yl)-N-methylpropan-1-amine Search by region : Germany

  • Name: 3-(11H-dibenzo[1,2-a:1',2'-e][7]annulen-11-yl)-N-methylpropan-1-amine
  • Synonyms: 3-(11H-dibenzo[1,2-a:1',2'-e][7]annulen-11-yl)-N-methylpropan-1-amine; Vivactil; Protryptyline; Impril; Rhotrimine; Novo-Tripramine; Novopramine; Apo-Imipramine; Triptil;Amimetilina;
  • CAS Registry Number:
  • Density: 1.026 g/cm3
  • EINECS: 207-119-9
  • Molecular Weight: 263.37674
  • InchiKey: BWPIARFWQZKAIA-UHFFFAOYSA-N
  • InChI: InChI=1S/C19H21N/c1-20-14-6-11-19-17-9-4-2-7-15(17)12-13-16-8-3-5-10-18
    (16)19/h2-5,7-10,12-13,19-20H,6,11,14H2,1H3
  • Molecular Formula: C19H21N
  • Molecular Structure:CAS No:438-60-8 3-(11H-dibenzo[1,2-a:1',2'-e][7]annulen-11-yl)-N-methylpropan-1-amine

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438-60-8 Protriptyline

  • Protriptyline
  • Germany CHEMOS GmbH [Manufacturer]
  • Tel: 0049 9402/9336 0
  • Fax: 0049 9402/9336 13
  • Address: CHEMOS GmbH
    Werner-von-Siemensstr. 3
    93128 Regenstauf
    Germany null,nullGermany
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References of 3-(11H-dibenzo[1,2-a:1',2'-e][7]annulen-11-yl)-N-methylpropan-1-amine
Title: Protriptyline
CAS Registry Number: 438-60-8
CAS Name: N-Methyl-5H-dibenzo[a,d]cycloheptene-5-propanamine
Synonyms: 5-(3-methylaminopropyl)-5H-dibenzo[a,d]cycloheptene; 7-(3-methylaminopropyl)-1,2:5,6-dibenzocycloheptatriene; amimetilina
Molecular Formula: C19H21N
Molecular Weight: 263.38
Percent Composition: C 86.64%, H 8.04%, N 5.32%
Literature References: Prepn: Engelhardt, Christy, BE 617967 (1962 to Merck & Co.), C.A. 59, 517f (1963); Tishler et al., US 3244748 and US 3271451 (both 1966 to Merck & Co.); Engelhardt et al., J. Med. Chem. 11, 325 (1968). Metabolism in man, pig and dog: Sisenwine et al., J. Pharmacol. Exp. Ther. 175, 51 (1970). Use in treatment of sleep apnea: R. W. Clark et al., Neurology 29, 1287 (1979); L. G. Brownell et al., N. Engl. J. Med. 307, 1037 (1982).
 
Derivative Type: Hydrochloride
CAS Registry Number: 1225-55-4
Manufacturers' Codes: MK-240
Trademarks: Concordin (Merck & Co.); Triptil (Merck & Co.); Vivactil (Merck & Co.)
Molecular Formula: C19H21N.HCl
Molecular Weight: 299.84
Percent Composition: C 76.11%, H 7.40%, N 4.67%, Cl 11.82%
Properties: Crystals from isopropanol-ethyl ether, mp 169-171°. uv max: 290 nm (e 13311). Freely sol in water. pKa 8.2.
Melting point: mp 169-171°
pKa: pKa 8.2
Absorption maximum: uv max: 290 nm (e 13311)
 
Therap-Cat: Antidepressant.
Keywords: Antidepressant; Tricyclics.