Title: Fenbendazole
CAS Registry Number: 43210-67-9
CAS Name: [5-(Phenylthio)-1
H-benzimidazol-2-yl]carbamic acid methyl ester
Synonyms: 5-(phenylthio)-2-benzimidazolecarbamic acid methyl ester; methyl 5-(phenylthio)-2-benzimidazolecarbamate
Manufacturers' Codes: HOE-881v
Trademarks: Panacur (Intervet)
Molecular Formula: C15H13N3O2S
Molecular Weight: 299.35
Percent Composition: C 60.18%, H 4.38%, N 14.04%, O 10.69%, S 10.71%
Literature References: Prepn: H. Loewe
et al., DE 2164690;
eidem, US 3954791 (1973, 1976 both to Hoechst); C. Baeder
et al., Experientia 30, 753 (1974). Efficacy vs gastrointestinal nematodes in swine: Enigk
et al., Dtsch. Tieraerztl. Wochenschr. 81, 177 (1974).
Properties: Light brownish-gray, odorless, tasteless crystalline powder, mp 233° (dec). Insol in water; insol or only very slightly sol in the usual solvents. Freely sol in DMSO.
Melting point: mp 233° (dec)
Therap-Cat-Vet: Anthelmintic (Nematodes).