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CAS No 42924-53-8 , 4-(6-methoxynaphthalen-2-yl)butan-2-one

  • Name: 4-(6-methoxynaphthalen-2-yl)butan-2-one
  • Synonyms: Listran; Consolan; Mebutan; Relif; Nabumetona; Arthaxan; Relifen;Relafen; Relifex;4-(6-methoxynaphthalen-2-yl)butan-2-one;
  • CAS Registry Number:
  • Melting Point: 80-810C
  • Density: 1.084 g/cm3
  • Refractive index: 1.572
  • Safety Statements: Moderately toxic by ingestion and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes.
  • Hazard Symbols: Xn
  • Molecular Weight: 228.28634
  • InchiKey: BLXXJMDCKKHMKV-UHFFFAOYSA-N
  • InChI: InChI=1S/C15H16O2/c1-11(16)3-4-12-5-6-14-10-15(17-2)8-7-13(14)9-12/h5-
    10H,3-4H2,1-2H3
  • Risk Statements: 22-40
  • Molecular Formula: C15H16O2
  • Molecular Structure:CAS No:42924-53-8 4-(6-methoxynaphthalen-2-yl)butan-2-one
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42924-53-8 NABUMETONE

  • China Ancheng Pharma Limited [Manufacturers]
  • Tel: +86-755-82713308
  • Fax: 0086-755-82713413
  • Address: Flat 1812, 18/F., Min Hua Building, 7 Jing Tian Bei Steet, Futian District,Shenzhen,China Shenzhen,guangdongChina
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42924-53-8 Nabumetone

  • China Levachem Co. Ltd. [Manufacturers]
  • Tel: 86-25-83247442 / 443 / 445 / 446 / 447
  • Fax: +86-25-83247441
  • Address: 2112, SuNing Universal Mansion, 188 Guangzhou Road, Nanjing-210024, China Nanjing,jiangsuChina
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42924-53-8 Nabumetone

  • Nabumetone
  • China Hallopharma [Manufacturer]
  • Tel: 0086-23-67030808
  • Fax: 0086-23-67030818
  • Address: 17F,Venus Science Incubate Center,No.60 Xingguang Road,New North Zone,401121 ChongqingCHINA Chongqing,nullChina
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42924-53-8 Nabumetone

  • Nabumetone
  • China Inter-Chemical [Manufacturer]
  • Tel: 0086-23-67030808
  • Fax: 0086-23-67030818
  • Address: 17F,Venus Science Incubate Center,No.60 Xingguang Road,New North Zone,401121 ChongqingCHINA Chongqing,nullChina
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42924-53-8 Nabumetone

  • China YANGZHOU CHEMICAL CO.,LTD. [Manufacturers]
  • Tel: 86-514-87864167
  • Fax: +86-514-87859301,87859302,87859303
  • Address: 7/F,18 WEST WENCHANG ROAD,YANGZHOU,JIANGSU,CHINA yangzhou,jiangsuChina
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42924-53-8 Nabumetone

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42924-53-8 Nabumetone

  • Nabumetone
  • China Tune Chemicals Co., Ltd [Manufacturer]
  • Tel: +86 571 85627657
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  • Address: Room 205D Harson Mansion Zhongshan Road310004 Hangzhou null,nullChina
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42924-53-8 Nabumetone

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42924-53-8 NABUMETONE

  • China Kangrui BIO-TECH Co.,Ltd.(H.K.) [Manufacturers]
  • Tel: 0086-571-86680744
  • Fax: 0086-571-86680744
  • Address: 3-704, Xixi Fengshang, Wensan West Road, Hangzhou, Zhejiang, China Hangzhou,ZhejiangChina
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42924-53-8 NABUMETONE

  • India VARDA Biotech (P) Ltd. [Manufacturer]
  • Tel: +91-22-6693 5686 / 2673 0141 / 2673 4258
  • Fax: +91-22-6693 5687
  • Address: 110 & 111, Kartik Complex
    New link Road, Andheri-(W)
    Mumbai-400053, INDIA. null,nullIndia
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References of 4-(6-methoxynaphthalen-2-yl)butan-2-one
Title: Nabumetone
CAS Registry Number: 42924-53-8
CAS Name: 4-(6-Methoxy-2-naphthalenyl)-2-butanone
Synonyms: 4-(6-methoxy-2-naphthyl)-butan-2-one
Manufacturers' Codes: BRL-14777
Trademarks: Arthaxan (GSK); Balmox (GSK); Consolan (Novo); Nabuser (Geymonat); Relafen (GSK); Relifen (GSK); Relifex (GSK)
Molecular Formula: C15H16O2
Molecular Weight: 228.29
Percent Composition: C 78.92%, H 7.06%, O 14.02%
Literature References: Nonacidic, lipophillic prodrug; metabolized in vivo to 6-methoxy-2-naphthylacetic acid which inhibits prostaglandin synthesis. Prepn: A. W. Lake, C. J. Rose, DE 2442305; eidem, US 4061779 (1975, 1977 both to Beecham); A. C. Goudie et al., J. Med. Chem. 21, 1260 (1978). Pharmacology: E. A. Boyle et al., J. Pharm. Pharmacol. 34, 562 (1982); B. Nunn, P. D. Chamberlain, ibid. 576. Metabolism: R. E. Haddock et al., Xenobiotica 14, 327 (1984). HPLC determn in plasma: J. E. Ray, R. O. Day, J. Chromatogr. 336, 234 (1984). Symposia on pharmacology, pharmacokinetics and clinical efficacy: Int. Congr. Symp. Ser. - R. Soc. Med. 69, 1-215 (1985); J. Rheumatol. 19, Suppl. 36, 1-91 (1992). Review: S. L. Dahl, Ann. Pharmacother. 27, 456-463 (1993).
Properties: Crystals from ethanol, mp 80°.
Melting point: mp 80°
Therap-Cat: Anti-inflammatory; analgesic.
Keywords: Anti-inflammatory (Nonsteroidal).