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CAS No 4093-35-0 , 4-amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide

  • Name: 4-amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide
  • Synonyms: 4093-35-0;Artomey; Valopride; Viaben; Emoril; Bromoprida [Spanish];4-amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide; Bromopridum [INN-Latin]; Emepride; Bromoprida [INN-Spanish];
  • CAS Registry Number:
  • Flash Point: 217.3°C
  • Boiling Point: 435.8°Cat760mmHg
  • Density: 1.313g/cm3
  • Refractive index: 1.565
  • Safety Statements: Poison by ingestion and intraperitoneal routes. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and Br−.
  • Hazard Symbols: Xn: Harmful;
  • Flash Point: 217.3°C
  • EINECS: 223-842-2
  • Molecular Weight: 344.24738
  • InchiKey: GIYAQDDTCWHPPL-UHFFFAOYSA-N
  • InChI: InChI=1S/C14H22BrN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)
    20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19)
  • Risk Statements: 20/21/22
  • Molecular Formula: C14H22BrN3O2
  • Molecular Structure:CAS No:4093-35-0 4-amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide

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References of 4-amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide
Title: Bromopride
CAS Registry Number: 4093-35-0
CAS Name: 4-Amino-5-bromo-N-[2-(diethylamino)ethyl]-2-methoxybenzamide
Synonyms: 4-amino-5-bromo-N-[2-(diethylamino)ethyl]-o-anisamide
Trademarks: Emepride (Roche); Emoril (Roemmers); Viadil (Pharma Investi)
Molecular Formula: C14H22BrN3O2
Molecular Weight: 344.25
Percent Composition: C 48.85%, H 6.44%, Br 23.21%, N 12.21%, O 9.30%
Literature References: Prepn: M. L. Thominet, BE 620543; idem, US 3177252 (1962, 1965 both to Soc. d'Etudes Sci. Ind. de l'Ile-de-France); H. Mori, K. Shibata, DE 2119724 (1971 to Teikoku Hormone Manuf. Co.), C.A. 76, 99375e (1972). Action on guinea-pig ileum: J. Fontaine, J. J. Reuse, Arch. Int. Pharmacodyn. Ther. 213, 322 (1975). Effects on intestinal peristalsis in dogs: P. Sava et al., Arzneim.-Forsch. 29, 799 (1979). Clinical study: M. Fischer et al., Fortschr. Med. 97, 883 (1979). Pharmacokinetics: P. W. Lücker et al., Arzneim.-Forsch. 33, 453 (1983).
 
Derivative Type: Hydrochloride
CAS Registry Number: 52423-56-0
Trademarks: Cascapride (Cascan); Plesium (Chiesi); Praiden (Italchemie); Valopride (Vita); Viaben (Schrholz)
Molecular Formula: C14H22BrN3O2.HCl
Molecular Weight: 380.71
Percent Composition: C 44.17%, H 6.09%, Br 20.99%, N 11.04%, O 8.41%, Cl 9.31%
 
Derivative Type: Dihydrochloride monohydrate
Trademarks: Opridan (Locatelli)
Molecular Formula: C14H22BrN3O2.2HCl.H2O
Molecular Weight: 435.18
Percent Composition: C 38.64%, H 6.02%, Br 18.36%, N 9.66%, O 11.03%, Cl 16.29%
 
Therap-Cat: Antiemetic.
Keywords: Antiemetic.