Home > Name List By 1 > 11-(1-methylpiperidin-4-ylidene)-5,6-dihydrobenzo[1,2]cyclohepta[3, 4-b]pyridine

CAS No 3964-81-6 , 11-(1-methylpiperidin-4-ylidene)-5,6-dihydrobenzo[1,2]cyclohepta[3,
4-b]pyridine

  • Name: 11-(1-methylpiperidin-4-ylidene)-5,6-dihydrobenzo[1,2]cyclohepta[3,
    4-b]pyridine
  • Synonyms: Azatidine; Azatadina; Azatadinum [INN-Latin];Optimine; Azatadina [INN-Spanish]; Azatadine [INN:BAN]; Azatadine maleate; Azatadinum;11-(1-methylpiperidin-4-ylidene)-5,6-dihydrobenzo[1,2]cyclohepta[3,
    4-b]pyridine;
  • CAS Registry Number:
  • Melting Point: 124-126ºC
  • Density: 1.127 g/cm3
  • EINECS: 223-615-8
  • Molecular Weight: 290.40208
  • InchiKey: SEBMTIQKRHYNIT-UHFFFAOYSA-N
  • InChI: InChI=1S/C20H22N2/c1-22-13-10-16(11-14-22)19-18-7-3-2-5-15(18)8-9-17-6-
    4-12-21-20(17)19/h2-7,12H,8-11,13-14H2,1H3
  • Molecular Formula: C20H22N2
  • Molecular Structure:CAS No:3964-81-6 11-(1-methylpiperidin-4-ylidene)-5,6-dihydrobenzo[1,2]cyclohepta[3,<br />4-b]pyridine

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References of 11-(1-methylpiperidin-4-ylidene)-5,6-dihydrobenzo[1,2]cyclohepta[3,
4-b]pyridine
Title: Azatadine
CAS Registry Number: 3964-81-6
CAS Name: 6,11-Dihydro-11-(1-methyl-4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
Synonyms: 4-aza-5-(N-methyl-4-piperidinylidene)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene
Molecular Formula: C20H22N2
Molecular Weight: 290.40
Percent Composition: C 82.72%, H 7.64%, N 9.65%
Literature References: Prepn: F. J. Villani, BE 647043 (1964 to Scherico); idem, US 3326924 (1967 to Schering); idem et al., J. Med. Chem. 15, 750 (1972). Pharmacology: S. Tozzi et al., Agents Actions 4, 264 (1974). Toxicity studies: H. Tanaka et al., Jitchuken Zenrinsho Kenkyuho 1, 173 (1975), C.A. 84, 25951h (1976). Clinical evaluation in allergic rhinitis: J. D. Wilson et al., N. Z. Med. J. 94, 79 (1981).
Properties: Crystals from isopropyl ether, mp 124-126°.
Melting point: mp 124-126°
 
Derivative Type: Dimaleate
CAS Registry Number: 3978-86-7
Manufacturers' Codes: Sch-10649
Trademarks: Bonamid (Heilmittelwerke); Idulian (Schering); Optimine (Schering); Zadine (Schering)
Molecular Formula: C20H22N2.2C4H4O4
Molecular Weight: 522.55
Percent Composition: C 64.36%, H 5.79%, N 5.36%, O 24.49%
Properties: Crystals from ethyl acetate-methanol, mp 152-154°.
Melting point: mp 152-154°
 
Therap-Cat: Antihistaminic.
Keywords: Antihistaminic; Tricyclics; Other Tricyclics.