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CAS No 390-28-3 , 2-amino-1-(2,5-dimethoxyphenyl)propan-1-ol

  • Name: 2-amino-1-(2,5-dimethoxyphenyl)propan-1-ol
  • Synonyms: Methoxamedrine; Metossamina [DCIT]; Vasoxine; Methoxamedrin; Vasoxyl; Methoxaminum; Pseudomethoxamine;2-amino-1-(2,5-dimethoxyphenyl)propan-1-ol; Methoxamin;
  • CAS Registry Number:
  • Flash Point: 176.6°C
  • Boiling Point: 368.4°Cat760mmHg
  • Density: g/cm3
  • Flash Point: 176.6°C
  • EINECS: 206-867-3
  • Molecular Weight: 211.25758
  • InchiKey: WJAJPNHVVFWKKL-UHFFFAOYSA-N
  • InChI: InChI=1S/C11H17NO3/c1-7(12)11(13)9-6-8(14-2)4-5-10(9)15-3/h4-7,11,13H,
    12H2,1-3H3
  • Molecular Formula: C11H17NO3
  • Molecular Structure:CAS No:390-28-3 2-amino-1-(2,5-dimethoxyphenyl)propan-1-ol

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390-28-3 Methoxamine

  • IUPAC NAME-2-amino-1-(2,5-dimethoxyphenyl)propan-1-ol MOLECULAR FORMULA-C11H17NO3 MOLAR MASS-211.258 Methoxamine is an α1-adrenergic receptor agonist similar in structure to phenylephrine and 2,5-DMA.
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390-28-3 Benzenemethanol,a-(1-aminoethyl)-2,5-dimethoxy-

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390-28-3 Methoxamine

  • Methoxamine, Min 99%
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390-28-3 Methoxamine

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390-28-3 Methoxamine

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390-28-3 Methoxamine

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390-28-3 Methoxamine

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390-28-3 METHOXAMINE

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References of 2-amino-1-(2,5-dimethoxyphenyl)propan-1-ol
Title: Methoxamine
CAS Registry Number: 390-28-3
CAS Name: a-(1-Aminoethyl)-2,5-dimethoxybenzenemethanol
Synonyms: a-(1-aminoethyl)-2,5-dimethoxybenzyl alcohol; 2-amino-1-(2,5-dimethoxyphenyl)-1-propanol; b-hydroxy-b-(2,5-dimethoxyphenyl)isopropylamine; b-(2,5-dimethoxyphenyl)-b-hydroxyisopropylamine; 2,5-dimethoxynorephedrine
Molecular Formula: C11H17NO3
Molecular Weight: 211.26
Percent Composition: C 62.54%, H 8.11%, N 6.63%, O 22.72%
Literature References: a1-Adrenergic agonist. Prepn: Baltzly et al., US 2359707 (1944 to Burroughs Wellcome). Metabolism: A. Klutch, M. Bordun, J. Med. Chem. 10, 860 (1967). Clinical pharmacology: N. T. Smith, C. Whitcher, Anesthesiology 28, 735 (1967); P. D. Snashall et al., Clin. Sci. Mol. Med. 54, 283 (1978). HPLC determn in plasma: I. A. Al-Meshal et al., J. Liq. Chromatogr. 12, 1589 (1989). Therapeutic use: P. M. C. Wright et al., Anesth. Analg. 75, 56 (1992); L. Cabanes et al., N. Engl. J. Med. 326, 1661 (1992). Comprehensive description: A. M. Al-Obaid, M. M. El-Domiaty, Anal. Profiles Drug Subs. 20, 399-431 (1991).
 
Derivative Type: Hydrochloride
CAS Registry Number: 61-16-5
Trademarks: Vasoxine (Burroughs Wellcome); Vasoxyl (Burroughs Wellcome); Vasylox (Burroughs Wellcome)
Molecular Formula: C11H17NO3.HCl
Molecular Weight: 247.72
Percent Composition: C 53.33%, H 7.32%, N 5.65%, O 19.38%, Cl 14.31%
Properties: Crystals, mp 212-216°. pKa (25°C) 9.2. Very sol in water: One gram dissolves in 2.5 ml water, in 12 ml ethanol. Practically insol in ether, benzene, chloroform. pH of a 2% aq soln between 4.5 and 5.5.
Melting point: mp 212-216°
pKa: pKa (25°C) 9.2
 
Therap-Cat: Antihypotensive.
Keywords: a-Adrenergic Agonist; Antihypotensive.