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CAS No 38677-85-9 , 2-[2-methyl-3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid

  • Name: 2-[2-methyl-3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid
  • Synonyms: Flunixinum [INN-Latin];Flunixine; Flunixino; 38677-85-9; Flunixino [INN-Spanish]; Flunixine [INN-French];2-[2-methyl-3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid; Sch 14714; Flunixinum;
  • CAS Registry Number:
  • Transport: UN2811 6.1/PG 3
  • Melting Point: 226 - 228 C
  • Flash Point: 182.8°C
  • Boiling Point: 378.7°C at 760 mmHg
  • Density: 1.403g/cm3
  • Refractive index: 1.582
  • Safety Statements: 26-36
  • Hazard Symbols: Xi,Xn
  • Flash Point: 182.8°C
  • EINECS: 255-836-0
  • Molecular Weight: 296.24455
  • InchiKey: NOOCSNJCXJYGPE-UHFFFAOYSA-N
  • InChI: InChI=1S/C14H11F3N2O2/c1-8-10(14(15,
    16)17)5-2-6-11(8)19-12-9(13(20)21)4-3-7-18-12/h2-7H,1H3,(H,18,19)(H,20,
    21)
  • Risk Statements: 36/37/38-22
  • Molecular Formula: C14H11F3N2O2
  • Molecular Structure:CAS No:38677-85-9 2-[2-methyl-3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid
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38677-85-9 FLUNIXINE

  • Hong kong Advanced Technology & Industrial Co., Ltd. [Manufacturer]
  • Tel: (852) 2390 2293/ (852) 2394 5546
  • Fax: (852) 2789 8314
  • Address: Unit B, 1/F., Cheong Shing Bldg.,
    17 Walnut St., Tai Kok Tsui, Kln,
    Hong Kong null,nullHong kong
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38677-85-9 3-Pyridinecarboxylicacid, 2-[[2-methyl-3-(trifluoromethyl)phenyl]amino]-

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38677-85-9 Flunixin

  • Flunixin
  • China Sunkingchem Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-28-88007744
  • Fax: +86-28-85193812
  • Address: A-703, Gaofa Building, Jiuxing Road 6#, Hi-Tech Zone 610041, Chengdu, Sichuan, China.610041 ChengduCHINA Chengdu,nullChina
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38677-85-9 Vadocaine

  • Vadocaine, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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38677-85-9 Flunixin

  • United States LGM Pharma [Manufacturer]
  • Tel: 561-981-9994
  • Fax: 561-892-0580
  • Address: 922 Clint Moore Road
    Boca Raton, FL 33487 null,nullUnited States
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38677-85-9 Flunixine

  • Flunixine, 99%
  • China Facus Pharmaceutical Co., Ltd. [Manufacturer]
  • Tel: +86-(0)574-62378411
  • Fax: +86-(0)574-62378410
  • Address: 24Fl,Yuanjing Building,Beilun District, Zhejiang 315800 NingboCHINA Ningbo,nullChina
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38677-85-9 Tobuterol, 99%

  • Tobuterol, 99%
  • China Pleapharma Co.,Ltd [Manufacturer]
  • Tel: 86 23 67030808
  • Fax: 86 23 67030809
  • Address: 22F,Jingxin center,No.70 Xingguang Road,Yubei Zone,Chongqing402232 chongqingCHINA chongqing,nullChina
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38677-85-9 Flunixin Meglumine

  • Flunixin Meglumine CAS: 38677-85-9 MF: C14H11F3N2O2 MW: 296.25 Description: White or almost white needle crystal powder. Stable. Imcompatible with strong bases, strong oxidizing agents. Usage: Cyclooxigenase inhibitor. Anti-inflammatory, analgesic, a...
  • China Jinan Jiaquan Chemical Co.,Ltd [Manufacturer, Trading Company]
  • Tel: 86-0531-62318366
  • Address: Room 502 of Yidonghuayuan No.6-1 Huaxin Road Licheng District Jinan,ShandongChina
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38677-85-9 Flunixine

  • Flunixine
  • China Hangzhou Pharma & Chem Co., Ltd. [Manufacturer]
  • Tel: +86 571 87040515
  • Fax: +86 571 87214761
  • Address: Hangzhou Pharma & Chem Co., Ltd.
    139 Qingchun Road, Hangzhou City,
    Zhejiang, China 310003 null,nullChina
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38677-85-9 FLUNIXIN MEGLUMINE

  • CBNumber: CB2471194 Chemical Name: FLUNIXIN MEGLUMINE Molecular Formula: C14H11F3N2O2 Formula Weight: 296.25 CAS No.: 38677-85-9 Usage Cyclooxigenase inhibitor. Anti-inflammatory; analgesic; antipyretic
  • China jinan jiaquan chemical [Manufacturer]
  • Tel: 86-531-62318366
  • Fax: 86-531-62318377
  • Address: Yidonghuayuan Huaxin Road Licheng District Jinan China jinan,nullChina
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References of 2-[2-methyl-3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid
Title: Flunixin
CAS Registry Number: 38677-85-9
CAS Name: 2-[[2-Methyl-3-(trifluoromethyl)phenyl]amino]-3-pyridinecarboxylic acid
Synonyms: 2-(2-methyl-3-trifluoromethylanilino)nicotinic acid; 2-(a3,a3,a3-trifluoro-2,3-xylidino)nicotinic acid
Manufacturers' Codes: Sch-14714
Molecular Formula: C14H11F3N2O2
Molecular Weight: 296.24
Percent Composition: C 56.76%, H 3.74%, F 19.24%, N 9.46%, O 10.80%
Literature References: Cyclooxygenase inhibitor. Prepn: M. H. Sherlock, N. Sperber, BE 679271; eidem, US 3337570 (1966, 1967 both to Schering). Prepn of the acid and meglumine salt: M. H. Sherlock, BE 812772; idem, US 3839344 (both 1974 to Schering). Pharmacodynamics in horses: M. M. Hardee, J. N. Moore, Res. Vet. Sci. 40, 152 (1986); and pharmacokinetics: L. R. Soma et al., J. Vet. Pharmacol. Ther. 15, 292 (1992). GC determn in urine: M. Johansson, E. -L. Anlér, J. Chromatogr. 427, 55 (1988). Clinical evaluation in horses: J. W. Houdeshell, P. W. Hennessey, J. Equine Med. Surg. 1, 57 (1977). Experimental use in food-producing animals: M. Kopcha, A. S. Ahl, J. Am. Vet. Med. Assoc. 194, 45 (1989). Comparative toxicological study in horses: C. G. MacAllister et al., ibid. 202, 71 (1993).
Properties: Crystals from acetone/hexane, mp 226-228°. pKa¢ 5.82.
Melting point: mp 226-228°
pKa: pKa¢ 5.82
 
Derivative Type: Meglumine salt
CAS Registry Number: 42461-84-7
Trademarks: Banamine (Schering-Plough); Binixin (Bayer); Finadyne (Fisons)
Molecular Formula: C14H11F3N2O2.C7H17NO5
Molecular Weight: 491.46
Percent Composition: C 51.32%, H 5.74%, F 11.60%, N 8.55%, O 22.79%
Properties: Colorless cryst from ethanol/ether, mp 135-137°. Crystals from acetonitrile, mp 136-139°. Sol in water.
Melting point: mp 135-137°; mp 136-139°
 
Therap-Cat-Vet: Anti-inflammatory; analgesic; antipyretic.