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CAS No 38304-91-5 , 3-hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine

  • Name: 3-hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine
  • Synonyms: Loniten; Alostil; Rogaine;3-hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine; Lonolox; Minoximen; Regaine; Theroxidil; Alopexil; Tricoxidil;
  • CAS Registry Number:
  • Melting Point: 272-274 °C (dec.)(lit.)
  • Density: 1.52 g/cm3
  • Refractive index: 1.724
  • Water Solubility: Soluble in ethanol (29mg/ml), DMSO (6.5mg/ml), and water (2.2mg/ml)
  • Safety Statements: S26-S36-S45-S36/37/39-S22
  • Hazard Symbols: Xn: Harmful;
  • EINECS: 253-874-2
  • Molecular Weight: 209.2483
  • InchiKey: ZIMGGGWCDYVHOY-UHFFFAOYSA-N
  • InChI: InChI=1S/C9H15N5O/c10-7-6-8(12-9(11)14(7)15)13-4-2-1-3-5-13/h6,11,15H,
    1-5,10H2
  • Risk Statements: R22-R36/37/38
  • Molecular Formula: C9H15N5O
  • Molecular Structure:CAS No:38304-91-5 3-hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine
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38304-91-5 3-hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine

  • Minoxidil Model NO.:FH-M-034 Minoxidil Appearance:White Crystalline Powder Minoxidil Purity:99% Minoxidil CAS No.:38304-91-5 Minoxidil Einecs No.:253-874-2 Minoxidil Function 1:Treating Male Pattern Alopecia. Minoxidil Function 2:Dropping The Blood P...
  • China Wuhan Yuancheng Technology Development Co., Ltd [Manufacturer, Trading Company, Distributor/Wholesaler]
  • Tel: 86-188-72220796
  • Address: No.496 Zhongshan Road, Wuchang District, Wuhan wuhan,HubeiChina
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38304-91-5 3-hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine

  • Minoxidil Model NO.:FH-M-034 Minoxidil Appearance:White Crystalline Powder Minoxidil Purity:99% Minoxidil CAS No.:38304-91-5 Minoxidil Einecs No.:253-874-2 Minoxidil Function 1:Treating Male Pattern Alopecia. Minoxidil Function 2:Dropping The Blood P...
  • China Hubei Yuancheng Hezhong Technology Co.,Ltd [Manufacturer, Trading Company]
  • Tel: 86-188-72220796
  • Address: No.496 wuhan,HubeiChina
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38304-91-5 3-hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine

  • Minoxidil CAS No.:38304-91-5 Minoxidil Einecs No.:253-874-2 Minoxidil Function 1:Treating Male Pattern Alopecia. Minoxidil Function 2:Dropping The Blood Pressure. Minoxidil Trademark:Frankherb Minoxidil Specification:USP / BP Minoxidil HS Code:293299...
  • China WuHan YuanCheng FeiChuang Technology Co.,Ltd [Manufacturer, Trading Company]
  • Tel: 86-188-72220796
  • Address: No.496 wuhan,HubeiChina
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38304-91-5 3-hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine

  • Minoxidil CAS No.:38304-91-5 Minoxidil Einecs No.:253-874-2 Minoxidil Function 1:Treating Male Pattern Alopecia. Minoxidil Function 2:Dropping The Blood Pressure. Minoxidil Trademark:Frankherb Minoxidil Specification:USP / BP Minoxidil HS Code:293299...
  • China WuHan YuanCheng GongChuang Technology Co.,Ltd [Manufacturer, Trading Company, Distributor/Wholesaler]
  • Tel: 86-188-72220796
  • Address: No.496 wuhan,HubeiChina
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38304-91-5 minoxidil

  • supply: 4cec 4cdc 4mpb bkebdp fubamb 5fabd mmbc 5F-ADB HEXEN, fubamb,4-cec,4-DCD,bk-ebdp,STG78,5fmdmb2201,4-mpd,4CLMPD,MDPHP,4eec,5cabp,mdpt,bmdp,2-fdck,mmaf buff BK-ebdp fubamb 5fadb Bromadoline 2fdck Skype:+86 17037496173 E-mail:cindy@hbmeihua.cn W...
  • Min. Order: 1000
  • FOB Price: USDfalse - false /
  • China Meihua Biological Technology Co.,Ltd [Manufacturer]
  • Tel: 86-311-83953206
  • Address: Dajing Street,Qiaoxi District Shijiazhuang City,HebeiChina
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38304-91-5 3-hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine

  • Isotretinoin CAS: 4759-48-2 Isotretinoin EINECS Number: 225-296-0 Isotretinoin Formula: C20H27O2 Isotretinoin MW: 299.4277 Isotretinoin Assay:99%
  • China Hubei Yuancheng Saichuang Technology Co,Ltd [Manufacturer, Trading Company, Distributor/Wholesaler]
  • Tel: 86-188-72220799
  • Address: No.496 ZhongShan Road, Wuchang District, Wuhan,Hubei wuhan,HubeiChina
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38304-91-5 3-hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine

  • Minoxidil CAS No.:38304-91-5 Minoxidil Einecs No.:253-874-2 Minoxidil Function 1:Treating Male Pattern Alopecia. Minoxidil Function 2:Dropping The Blood Pressure. Minoxidil Trademark:Frankherb Minoxidil Specification:USP / BP Minoxidil HS Code:293299...
  • China Hubei Yuancheng Saisi Technology Co., Ltd [Manufacturer, Trading Company, Distributor/Wholesaler]
  • Tel: 86-188-72220796
  • Address: No.496,Wuchang Distreet wuhan,HubeiChina
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38304-91-5 Minoxidil

  • Product Name: Minoxidil Synonyms:alopexil CAS: 38304-91-5 MF: C9H15N5O MW: 209.25 EINECS:253-874-2 Chemical Properties: White Crystalline Solid Application: Minoxidil is an antihypertensive drug and a hair growth stimulant Vasodilator; treatment of h...
  • Min. Order: 1000
  • China Jinan Jiage Biological Technology Co., Ltd [Manufacturer]
  • Tel: 86-156-50036328
  • Address: Luneng Cambridge,Tianqiao District,Jinan,Shandong Jinan,ShandongChina
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38304-91-5 CAS 38304-91-5 Minoxidil

  • CAS 38304-91-5 Minoxidil Product Name: Minoxidil Alias: Ioniten,Monoxodyl,Lonolox CAS: 38304-91-5 EINECS: 253-874-2 Molecular Formula: C9H15N5O Molecular Weight: 209.25 Purity: 99% Grade: Pharmaceutical Grade Appearance: White Or Almost White Crystal...
  • Min. Order: 500
  • FOB Price: USDfalse - false /
  • China Jianan Jiage Biological Technology Co., Ltd [Manufacturer]
  • Tel: 86-0531-85826061
  • Address: NO.19 Lunengkang Bridge, Platform Bridge District JiNan,ShandongChina
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38304-91-5 Minoxidil

  • Minoxidil Product name: Minoxidil Other name: Minoxidil (Subject To Patent Free); Minoxidil Base CAS No.: 38304-91-5 Assay: 99% Packing: 25kg/drum M.F.: C9H15N5O M.W.: 209.25 Reference standard: USP Appearance: White or white crystalline powder
  • China Hubei Yuancheng Pharmaceutical Co., Ltd [Manufacturer]
  • Tel: 086-027-50756084
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  • Address: Zhongshan Road Wuhan,HubeiChina
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References of 3-hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine
Title: Minoxidil
CAS Registry Number: 38304-91-5
CAS Name: 6-(1-Piperidinyl)-2,4-pyrimidinediamine 3-oxide
Synonyms: 6-amino-1,2-dihydro-1-hydroxy-2-imino-4-piperidinopyrimidine; 2,3-dihydro-3-hydroxy-2-imino-6-(1-piperidinyl)-4-pyrimidinamine; 2,4-diamino-6-piperidinopyrimidine 3-oxide; 6-piperidino-2,4-diaminopyrimidine 3-oxide; PDP
Manufacturers' Codes: U-10858
Trademarks: Alopexil (Fabre); Alostil (Pfizer); Loniten (Pfizer); Lonolox (Pfizer); Minoximen (Menarini); Normoxidil (Medosan); Prexidil (Bioindustria); Regaine (Pfizer); Rogaine (Pfizer); Tricoxidil (Pfizer)
Molecular Formula: C9H15N5O
Molecular Weight: 209.25
Percent Composition: C 51.66%, H 7.23%, N 33.47%, O 7.65%
Literature References: Prepn: NL 6615385; W. C. Anthony et al., US 3382247 (1967, 1968 both to Upjohn); J. M. McCall et al., J. Org. Chem. 40, 3304 (1975). See also W. C. Anthony, US 3644364 (1972 to Upjohn). Metabolism: R. C. Thomas et al., J. Pharm. Sci. 64, 1360 (1975). Pharmacology and pharmacokinetics: D. T. Lowenthal et al., J. Clin. Pharmacol. 18, 500 (1978). Percutaneous absorption and excretion: T. J. Franz, Arch. Dermatol. 121, 203 (1985). Clinical studies: O. Andersson, R. Sivertsson, Acta Med. Scand. 205, 213 (1979); M. Moser, Adv. Cardiol. 26, 38 (1979). Clinical trial in early male pattern baldness: E. A. Olsen et al., J. Am. Acad. Dermatol. 13, 185 (1985). Toxicology: R. G. Carlson, E. S. Feenstra, Toxicol. Appl. Pharmacol. 39, 1 (1977). Review of pharmacology and therapeutic use: V. M. Campese, Drugs 22, 257-278 (1981). Review of topical application in baldness: E. Novak et al., Int. J. Dermatol. 24, 82 (1985). Comprehensive description: D. K. J. Gorecki, Anal. Profiles Drug Subs. 17, 185-219 (1988).
Properties: Crystals from methanol-acetonitrile, mp 248°, dec 259-261° (Anthony, 1972). pKa 4.61. uv max (ethanol): 230, 261, 285 nm (e 35210, 11210, 11790); (0.01N H2SO4): 232, 280 nm (e 26350, 23850); (0.01N KOH): 231, 261.5, 285 nm (e 36100, 11400, 12040). Soly (mg/ml): propylene glycol 75, methanol 44, ethanol 29, 2-propanol 6.7, dimethylsulfoxide 6.5, water 2.2, chloroform 0.5, acetone <0.5, ethylacetate <0.5, diethyl ether <0.5, benzene <0.5, acetonitrile <0.5. LD50 in rats, mice (mg/kg): 49, 51 i.v. (Carlson, Feenstra).
Melting point: mp 248°
pKa: pKa 4.61
Absorption maximum: uv max (ethanol): 230, 261, 285 nm (e 35210, 11210, 11790); (0.01N H2SO4): 232, 280 nm (e 26350, 23850); (0.01N KOH): 231, 261.5, 285 nm (e 36100, 11400, 12040)
Toxicity data: LD50 in rats, mice (mg/kg): 49, 51 i.v. (Carlson, Feenstra)
Therap-Cat: Antihypertensive. Antialopecia agent.
Keywords: Antialopecia Agent; Antihypertensive.