Home > Name List By 2 > 2,6-Methano-3-benzazocin-8-ol,3-(cyclopropylmethyl)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-

CAS No 3572-80-3 , 2,6-Methano-3-benzazocin-8-ol,3-(cyclopropylmethyl)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-

  • Name: 2,6-Methano-3-benzazocin-8-ol,3-(cyclopropylmethyl)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-
  • Synonyms: Cyclazocine [USAN:INN]; WIN 20740;Ciclazocina; Cyclazocinum [INN-Latin]; Cyclazocinum; UM 407; 3572-80-3; NIH 7981;2,6-Methano-3-benzazocin-8-ol,3-(cyclopropylmethyl)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-;
  • CAS Registry Number:
  • Flash Point: 188.7°C
  • Boiling Point: 399.2°Cat760mmHg
  • Density: 1.123g/cm3
  • Refractive index: 1.591
  • Safety Statements: A poison by subcutaneous, intravenous, and intraperitoneal routes. Experimental reproductive effects. Used in the treatment of narcotic addiction. When heated to decomposition it emits toxic fumes of NOx.
  • Flash Point: 188.7°C
  • EINECS: 222-689-9
  • Molecular Weight: 271.3972
  • InchiKey: YQYVFVRQLZMJKJ-UHFFFAOYSA-N
  • InChI: InChI=1S/C18H25NO/c1-12-17-9-14-5-6-15(20)10-16(14)18(12,
    2)7-8-19(17)11-13-3-4-13/h5-6,10,12-13,17,20H,3-4,7-9,11H2,1-2H3
  • Molecular Formula: C18H25NO
  • Molecular Structure:CAS No:3572-80-3 2,6-Methano-3-benzazocin-8-ol,3-(cyclopropylmethyl)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-

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References of 2,6-Methano-3-benzazocin-8-ol,3-(cyclopropylmethyl)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-
Title: Cyclazocine
CAS Registry Number: 3572-80-3
CAS Name: 3-(Cyclopropylmethyl)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-2,6-methano-3-benzazocin-8-ol
Manufacturers' Codes: Win-20740; NSC-107429
Molecular Formula: C18H25NO
Molecular Weight: 271.40
Percent Composition: C 79.66%, H 9.28%, N 5.16%, O 5.90%
Literature References: Analgesic with mixed narcotic agonist-antagonist properties. Prepn: Archer, BE 611000 (1962 to Sterling Drug), C.A. 58, 2439c (1963). Crystal structure: I. L. Karle et al., Acta Crystallogr. B25, 1469 (1969). Supraspinal analgesic effects: S. Sasson, C. Kornetsky, Life Sci. 38, 21 (1986). Evaluation in anorexia and motor disruption in rats: J. W. Henck et al., Pharmacol. Biochem. Behav. 22, 671 (1985). Determn by HPLC: I. Jane, A. McKinnon, J. Chromatogr. 323, 191 (1985). Review of use in treatment of opiate addiction: M. J. Goldstein, Int. J. Addict. 15, 939 (1980).
Properties: Crystals from methanol, mp 201-204°.
Melting point: mp 201-204°
Therap-Cat: Narcotic antagonist.
Keywords: Narcotic Antagonist.