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CAS No 3572-43-8 , 2,4-dibromo-6-[[cyclohexyl(methyl)amino]methyl]aniline

  • Name: 2,4-dibromo-6-[[cyclohexyl(methyl)amino]methyl]aniline
  • Synonyms: Bromhexinum [INN-Latin]; Bromhexine [INN:BAN]; Benzenemethanamine;2,4-dibromo-6-[[cyclohexyl(methyl)amino]methyl]aniline;3572-43-8; 2-amino-3,5-dibromo-N-cyclohexyl-N-methyl-;
  • CAS Registry Number:
  • Density: 1.57 g/cm3
  • Refractive index: 1.626
  • EINECS: 222-684-1
  • Molecular Weight: 376.13
  • InchiKey: OJGDCBLYJGHCIH-UHFFFAOYSA-N
  • InChI: InChI=1S/C14H20Br2N2/c1-18(12-5-3-2-4-6-12)9-10-7-11(15)8-13(16)14(10)
    17/h7-8,12H,2-6,9,17H2,1H3
  • Molecular Formula: C14H20Br2N2
  • Molecular Structure:CAS No:3572-43-8 2,4-dibromo-6-[[cyclohexyl(methyl)amino]methyl]aniline

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3572-43-8 Bromhexine

  • IUPAC NAME-2,4-dibromo-6-{[cyclohexyl(methyl)amino]methyl}aniline MOLECULAR FORMULA-C14H20Br2N2 MOLAR MASS-376.13 Bromhexine is a mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus. In addition, b...
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3572-43-8 Bamifylline

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3572-43-8 Bamifylline

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3572-43-8 Bromhexine

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3572-43-8 BROMHEXINE

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3572-43-8 Bisolvon, 99%

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3572-43-8 Bromhexine

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References of 2,4-dibromo-6-[[cyclohexyl(methyl)amino]methyl]aniline
Title: Bromhexine
CAS Registry Number: 3572-43-8
CAS Name: 2-Amino-3,5-dibromo-N-cyclohexyl-N-methylbenzenemethanamine
Synonyms: 3,5-dibromo-Na-cyclohexyl-Na-methyltoluene-a,2-diamine; N-cyclohexyl-N-methyl-2-(2-amino-3,5-dibromo)benzylammonium; N-(2-amino-3,5-dibromobenzyl)-N-methylcyclohexylammonium
Molecular Formula: C14H20Br2N2
Molecular Weight: 376.13
Percent Composition: C 44.71%, H 5.36%, Br 42.49%, N 7.45%
Literature References: Prepn: Keck, Ann. 662, 171 (1963); K. Thomae, BE 625022 (1963), C.A. 61, 5564 (1964). Pharmacology: R. Engelhorn, S. Püschmann, Arzneim.-Forsch. 13, 474 (1963). Metabolism: R. Jauch et al., ibid. 25, 1954 (1975). Toxicity: Boyd, Sheppard, Arch. Int. Pharmacodyn. Ther. 163, 284 (1966).
Properties: Crystals from abs ethanol, dec 237.5-238°. One gram dissolves in 250 ml of water or 10% ethanol. Approx LD50 orally in rabbits: >10 g/kg (Boyd, Sheppard).
Toxicity data: Approx LD50 orally in rabbits: >10 g/kg (Boyd, Sheppard)
 
Derivative Type: Hydrochloride
CAS Registry Number: 611-75-6
Manufacturers' Codes: NA-274
Trademarks: Auxit (BMS); Bisolvon (Thomae); Ophtosol (Winzer); Quentan (Boehringer, Ing.)
Molecular Formula: C14H20Br2N2.HCl
Molecular Weight: 412.59
Percent Composition: C 40.75%, H 5.13%, Br 38.73%, N 6.79%, Cl 8.59%
 
Therap-Cat: Expectorant; mucolytic.
Therap-Cat-Vet: Expectorant.
Keywords: Expectorant; Mucolytic.