Home > Name List By 1 > 1-(tert-butylamino)-3-(3,4-dihydro-2H-thiochromen-8-yloxy)propan-2-ol

CAS No 34784-64-0 , 1-(tert-butylamino)-3-(3,4-dihydro-2H-thiochromen-8-yloxy)propan-2-ol

  • Name: 1-(tert-butylamino)-3-(3,4-dihydro-2H-thiochromen-8-yloxy)propan-2-ol
  • Synonyms: EINECS 280-519-9;1-(tert-butylamino)-3-(3,4-dihydro-2H-thiochromen-8-yloxy)propan-2-ol; Racemic teraterol; S-2395; Tertatolol [BAN:INN]; Tertatololum [Latin]; dl-Tertatalol; Tertatololum;dl-Tertatolol;
  • CAS Registry Number:
  • Molecular Weight: 295.4402
  • InchiKey: HTWFXPCUFWKXOP-UHFFFAOYSA-N
  • InChI: InChI=1S/C16H25NO2S/c1-16(2,
    3)17-10-13(18)11-19-14-8-4-6-12-7-5-9-20-15(12)14/h4,6,8,13,17-18H,5,7,
    9-11H2,1-3H3
  • Molecular Formula: C16H25NO2S
  • Molecular Structure:CAS No:34784-64-0 1-(tert-butylamino)-3-(3,4-dihydro-2H-thiochromen-8-yloxy)propan-2-ol

Related products

Select to

34784-64-0 Tertatolol

  • Tertatolol, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
Contact Supplier

34784-64-0 Tertatolol

  • Tertatolol
  • China interchem [Manufacturer]
  • Tel: +86-23-67030787
  • Fax: +86-23-67030809
  • Address: 17F.,Venus science incubation center,No.60 xingguang road,New north zone,Chongqing,China 401121 ChongiqngCHINA Chongiqng,nullChina
Contact Supplier

34784-64-0 TERTATOLOL

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
Contact Supplier

Select to

1/1
References of 1-(tert-butylamino)-3-(3,4-dihydro-2H-thiochromen-8-yloxy)propan-2-ol
Title: Tertatolol
CAS Registry Number: 34784-64-0
CAS Name: 1-[(3,4-Dihydro-2H-1-benzothiopyran-8-yl)oxy]-3-[(1,1-dimethylethyl)amino]-2-propanol
Synonyms: (±)-1-tert-butylamino-3-(1-thiachroman-8-yloxy)-2-propanol; dl-8-[2-hydroxy-3-[(tert-butylamino)propyl]oxy]thiochromane
Molecular Formula: C16H25NO2S
Molecular Weight: 295.44
Percent Composition: C 65.05%, H 8.53%, N 4.74%, O 10.83%, S 10.85%
Literature References: Nonselective b-adrenergic blocker. Prepn: C. Malen, M. Laubie, DE 2115201; eidem, US 3960891 (1971, 1976 both to Sci. Union et Cie). Pharmacology in animals: M. Laubie et al., Arch. Int. Pharmacodyn. Ther. 201, 323, 334 (1973); B. R. Walker et al., J. Cardiovasc. Pharmacol. 7, 1193 (1985). Synergistic effect with indapamide, q.v.: E. Marmo et al., Drugs Exp. Clin. Res. 11, 709 (1985). GC-MS determn in plasma and urine: S. Staveris et al., J. Chromatogr. 339, 97 (1985). Pharmacology in humans and mechanism of action study: A. De Blasi et al., Clin. Pharmacol. Ther. 39, 245 (1986). Preliminary evaluation in hypertension: J. P. Degaute et al., Am. J. Hypertens. 1, 263S (1988).
Properties: Crystals from hexane, mp 70-72°.
Melting point: mp 70-72°
 
Derivative Type: Hydrochloride
CAS Registry Number: 33580-30-2
Manufacturers' Codes: S-2395; SE-2395
Trademarks: Artex (Servier); Artexal (Servier); Prenalex (Itherapia)
Molecular Formula: C16H25NO2S.HCl
Molecular Weight: 331.90
Percent Composition: C 57.90%, H 7.90%, N 4.22%, O 9.64%, S 9.66%, Cl 10.68%
Properties: Crystals from acetonitrile, mp 180-183°. pKa 9.8. LD50 in rats, mice (mg/kg): 40, 37 i.v.; 90, 120 i.p. (Laubie).
Melting point: mp 180-183°
pKa: pKa 9.8
Toxicity data: LD50 in rats, mice (mg/kg): 40, 37 i.v.; 90, 120 i.p. (Laubie)
 
Therap-Cat: Antihypertensive.
Keywords: ?Adrenergic Blocker; Antihypertensive; Aryloxypropanolamine Derivatives.