References of 3-(morpholin-4-ylmethyl)-1-[(E)-(5-nitrofuran-2-yl)methylideneamino]
imidazolidine-2,4-dione
Title: Nifurfoline
CAS Registry Number: 3363-58-4
CAS Name: 3-(4-Morpholinylmethyl)-1-[[(5-nitro-2-furanyl)methylene]amino]-2,4-imidazolidinedione
Synonyms: 3-(morpholinomethyl)-1-[(5-nitrofurfurylidene)amino]hydantoin
Trademarks: Urbac (Merck-Cl¢enot)
Molecular Formula: C13H15N5O6
Molecular Weight: 337.29
Percent Composition: C 46.29%, H 4.48%, N 20.76%, O 28.46%
Literature References: Prepn: J. A. Bofill-Auge, J. M. Espinos-Taya,
ES 297087 (1964),
C.A. 63, 11572e (1966);
GB 1245095 (1971 to Esteve),
C.A. 75, 121382h (1971).
Properties: Yellow cryst, mp 206°; also reported as mp 194-196°, J. Klosa, H. Starke,
DD 508615 (1966),
C.A. 66, 65501w (1967).
Melting point: mp 206°; also reported as mp 194-196°
Therap-Cat: Antibacterial.
Keywords: Antibacterial (Synthetic); Nitrofurans.