Home > Name List By n > N-(2,6-dichlorophenyl)-N-prop-2-enyl-4,5-dihydro-1H-imidazol-2-amine

CAS No 33178-86-8 , N-(2,6-dichlorophenyl)-N-prop-2-enyl-4,5-dihydro-1H-imidazol-2-amine

  • Name: N-(2,6-dichlorophenyl)-N-prop-2-enyl-4,5-dihydro-1H-imidazol-2-amine
  • Synonyms: 33178-86-8; Alinidinum [INN-Latin]; 2-(N-Allyl-N-(2,6-dichlorophenyl)amino)-2-imidazoline;Alinidin; Alinidina [INN-Spanish]; ST-567;N-(2,6-dichlorophenyl)-N-prop-2-enyl-4,5-dihydro-1H-imidazol-2-amine;
  • CAS Registry Number:
  • Flash Point: 171.7°C
  • Boiling Point: 360.2°Cat760mmHg
  • Density: 1.3g/cm3
  • Refractive index: 1.611
  • Flash Point: 171.7°C
  • Molecular Weight: 270.15772
  • InchiKey: OXTYVEUAQHPPMV-UHFFFAOYSA-N
  • InChI: InChI=1S/C12H13Cl2N3/c1-2-8-17(12-15-6-7-16-12)11-9(13)4-3-5-10(11)14/
    h2-5H,1,6-8H2,(H,15,16)
  • Molecular Formula: C12H13Cl2N3
  • Molecular Structure:CAS No:33178-86-8 N-(2,6-dichlorophenyl)-N-prop-2-enyl-4,5-dihydro-1H-imidazol-2-amine

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33178-86-8 Alinidine

  • Alinidine, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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33178-86-8 Alinidine

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33178-86-8 1H-Imidazol-2-amine,N-(2,6-dichlorophenyl)-4,5-dihydro-N-2-propen-1-yl-

  • China Guangzhou WeiBo Chemical Co., Ltd. [Importer/Exporter]
  • Tel: 020-33640779 32416961
  • Fax: 020-26277554
  • Address: NO.1002-39,jinbi building,shijinshicha road,baiyun district,guanghzou city guangzhou,guangdongChina
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33178-86-8 1H-Imidazol-2-amine,N-(2,6-dichlorophenyl)-4,5-dihydro-N-2-propen-1-yl-

  • China NANTONG CHEM-TECH.(GROUP) CO.,LTD [Manufacturers]
  • Tel: 0086-513-85081108 85335860
  • Fax: 0086-513-85085921
  • Address: 7/F Beihao BLDG, No. 91,Zhongxiu Middle Road, Nantong,China Nantong,jiangsuChina
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33178-86-8 ALINIDINE

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
    No. 217 Zhongshan Rd.
    (N)Nanjing 210009,China null,nullChina
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References of N-(2,6-dichlorophenyl)-N-prop-2-enyl-4,5-dihydro-1H-imidazol-2-amine
Title: Alinidine
CAS Registry Number: 33178-86-8
CAS Name: N-(2,6-Dichlorophenyl)-4,5-dihydro-N-2-propenyl-1H-imidazol-2-amine
Synonyms: 2-(N-allyl-2,6-dichloroanilino)-2-imidazoline; 2-[N-allyl-N-(2,6-dichlorophenyl)amino]-2-imidazoline
Manufacturers' Codes: ST-567
Molecular Formula: C12H13Cl2N3
Molecular Weight: 270.16
Percent Composition: C 53.35%, H 4.85%, Cl 26.25%, N 15.55%
Literature References: Specific bradycardic agent; analog of clonidine, q.v. Prepn: H. St?hle et al., DE 1958201; eidem, US 3708485 (1971, 1973 both to Boehringer, Ing.); eidem, J. Med. Chem. 23, 1217 (1980). Clinical pharmacology: D. W. G. Harron et al., J. Cardiovasc. Pharmacol. 4, 213 (1982). Mode of action study: J. S. Millar, E. M. Vaughan Williams, Lancet 1, 1291 (1981). HPLC determn in human plasma: U.-W. Wiegand et al., J. Chromatogr. 223, 238 (1981). Clinical pharmacokinetics: eidem, J. Cardiovasc. Pharmacol. 4, 59 (1982). Hemodynamic effects in angina or infarction: M. L. Simoons, P. G. Hugenholtz, Eur. Heart J. 5, 227 (1984). Review of pharmacology and potential therapeutic uses: D. W. G. Harron, R. G. Shanks, ibid. 6, 722-729 (1985).
Properties: Crystals, mp 130-131° (St?hle, 1973); also reported as mp 127-129° (St?hle, 1980). pKa 10.42.
Melting point: mp 130-131° (St?hle, 1973); mp 127-129° (St?hle, 1980)
pKa: pKa 10.42
 
Derivative Type: Hydrobromide
Molecular Formula: C12H14BrCl2N3
Molecular Weight: 351.07
Percent Composition: C 41.05%, H 4.02%, Br 22.76%, Cl 20.20%, N 11.97%
Properties: Crystals from methanol + water, mp 193-194°.
Melting point: mp 193-194°