Home > Name List By other > (1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-6-sulfo-2,3,4,9,10, 10a-hexahydrophenanthrene-1-carboxylic acid

CAS No 33159-27-2 , (1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-6-sulfo-2,3,4,9,10,
10a-hexahydrophenanthrene-1-carboxylic acid

  • Name: (1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-6-sulfo-2,3,4,9,10,
    10a-hexahydrophenanthrene-1-carboxylic acid
  • Synonyms: Ecabet [INN]; Ecabet (INN); Gastrom; Ecabetum;(1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-6-sulfo-2,3,4,9,10,
    10a-hexahydrophenanthrene-1-carboxylic acid;ecabet sodium; 12-sulfodehydroabietic acid; Ecabetum [INN-Latin]; NCGC00181160-01;
  • CAS Registry Number:
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: 1.241 g/cm3
  • Refractive index: 1.562
  • Flash Point: °C
  • Molecular Weight: 380.49832
  • InchiKey: IWCWQNVIUXZOMJ-MISYRCLQSA-N
  • InChI: InChI=1S/C20H28O5S/c1-12(2)14-10-13-6-7-17-19(3,8-5-9-20(17,
    4)18(21)22)15(13)11-16(14)26(23,24)25/h10-12,17H,5-9H2,1-4H3,(H,21,
    22)(H,23,24,25)/t17-,19-,20-/m1/s1
  • Molecular Formula: C20H28O5S
  • Molecular Structure:CAS No:33159-27-2 (1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-6-sulfo-2,3,4,9,10,<br />10a-hexahydrophenanthrene-1-carboxylic acid

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33159-27-2 Ecabet

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References of (1R,4aS,10aR)-1,4a-dimethyl-7-propan-2-yl-6-sulfo-2,3,4,9,10,
10a-hexahydrophenanthrene-1-carboxylic acid
Title: Ecabet
CAS Registry Number: 33159-27-2
CAS Name: (1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-Octahydro-1,4a-dimethyl-7-(1-methylethyl)-6-sulfo-1-phenanthrenecarboxylic acid
Synonyms: dehydro-6-sulfoabietic acid; 12-sulfodehydroabietic acid
Molecular Formula: C20H28O5S
Molecular Weight: 380.50
Percent Composition: C 63.13%, H 7.42%, O 21.02%, S 8.43%
Literature References: Prepn: L. F. Fieser, W. P. Campbell, J. Am. Chem. Soc. 60, 2631 (1938); H. Wada et al., Chem. Pharm. Bull. 33, 1472 (1985). Metabolism in animals: Y. Ito et al., J. Pharmacobio-Dyn. 14, 533 (1991). Efficacy in healing expt ulcers in rats: Y. Onoda et al., Arzneim.-Forsch. 41, 546 (1991). Gastroprotective effects in rats in comparison with sucralfate, q.v.: M. Kinoshita et al., Dig. Dis. Sci. 40, 661 (1995). Bactericidal activity against Helicobacter pylori: K. Shibata et al., Antimicrob. Agents Chemother. 39, 1295 (1995).
Properties: As the hemihydrate, [a]D25 +72.4° (c = 2.5 in alcohol).
Optical Rotation: [a]D25 +72.4° (c = 2.5 in alcohol)
 
Derivative Type: Sodium salt
CAS Registry Number: 86408-72-2
Manufacturers' Codes: TA-2711
Trademarks: Gastron (Tanabe)
Molecular Formula: C20H27NaO5S
Molecular Weight: 402.48
Percent Composition: C 59.68%, H 6.76%, Na 5.71%, O 19.88%, S 7.97%
Properties: Occurs as pentahydrate, mp >300°. [a]D20 +59.4° (c = 0.5).
Melting point: mp >300°
Optical Rotation: [a]D20 +59.4° (c = 0.5)
 
Therap-Cat: Antiulcerative.
Keywords: Antiulcerative.