Home > Name List By c > Cyclo[(2Z)-3-[(aminocarbonyl)amino]-2,3-didehydroalanyl-(2S)-2-[(4R)-2-amino-3,4,5,6-tetrahydro-4-pyrimidinyl]glycyl-(2S)-2-[...

CAS No 33103-22-9 , Cyclo[(2Z)-3-[(aminocarbonyl)amino]-2,3-didehydroalanyl-(2S)-2-[(4R)-2-amino-3,4,5,6-tetrahydro-4-pyrimidinyl]glycyl-(2S)-2-[[(3R,4R)-3,6-diamino-4-hydroxy-1-oxohexyl]amino]-b-alanyl-L-seryl-L-seryl]

  • Name: Cyclo[(2Z)-3-[(aminocarbonyl)amino]-2,3-didehydroalanyl-(2S)-2-[(4R)-2-amino-3,4,5,6-tetrahydro-4-pyrimidinyl]glycyl-(2S)-2-[[(3R,4R)-3,6-diamino-4-hydroxy-1-oxohexyl]amino]-b-alanyl-L-seryl-L-seryl]
  • Synonyms: Viomycin, 1-[(3R,4R)-4-hydroxy-3,6-diaminohexanoicacid]-6-[L-2-(2-amino-1,4,5,6-tetrahydro-4-pyrimidinyl)glycine]-, (R)-;1,4,7,10,13-Pentaazacyclohexadecane, cyclic peptide deriv.;Cyclo[(2Z)-3-[(aminocarbonyl)amino]-2,3-didehydroalanyl-(2S)-2-[(4R)-2-amino-3,4,5,6-tetrahydro-4-pyrimidinyl]glycyl-(2S)-2-[[(3R,4R)-3,6-diamino-4-hydroxy-1-oxohexyl]amino]-b-alanyl-L-seryl-L-seryl];TuberactinomycinN (8CI,9CI); Enviomycin;
  • CAS Registry Number:
  • Flash Point: °C
  • Boiling Point: °Cat760mmHg
  • Density: 1.8g/cm3
  • Refractive index: 1.762
  • Flash Point: °C
  • Molecular Weight: 0
  • InChI: InChI=1/C25H43N13O10/c26-3-1-16(41)10(27)5-17(42)33-12-6-31-23(47)18(11-2-4-30-24(28)37-11)38-20(44)13(7-32-25(29)48)34-21(45)14(8-39)36-22(46)15(9-40)35-19(12)43/h7,10-12,14-16,18,39-41H,1-6,8-9,26-27H2,(H,31,47)(H,33,42)(H,34,45)(H,35,43)(H,36,46)(H,38,44)(H3,28,30,37)(H3,29,32,48)/b13-7-
  • Molecular Formula: C25H43 N13 O10
  • Molecular Structure:CAS No:33103-22-9 Cyclo[(2Z)-3-[(aminocarbonyl)amino]-2,3-didehydroalanyl-(2S)-2-[(4R)-2-amino-3,4,5,6-tetrahydro-4-pyrimidinyl]glycyl-(2S)-2-[[(3R,4R)-3,6-diamino-4-hydroxy-1-oxohexyl]amino]-b-alanyl-L-seryl-L-seryl]

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33103-22-9 Tuberactinomycin N

  • Tuberactinomycin N, Min 99%
  • China Finechemie Co., Ltd. [Manufacturer]
  • Tel: +86-23-99186710
  • Fax: +86-23-99186729
  • Address: 28th Floor Mordern Building,New-Tech Zone400020 ChongqingCHINA Chongqing,nullChina
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33103-22-9 Enviomycin

  • Enviomycin
  • Germany CHEMOS GmbH [Manufacturer]
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    93128 Regenstauf
    Germany null,nullGermany
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33103-22-9 ENVIOMYCIN

  • China Nanjing Chemlin Chemical Industry Co.,Ltd. [Manufacturer]
  • Tel: +86 25 8369-7070/ +86 138 51816776 (Mobile)
  • Fax: +86 25 8345-3275
  • Address: Rm.902 Longyin Plaza,
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References of Cyclo[(2Z)-3-[(aminocarbonyl)amino]-2,3-didehydroalanyl-(2S)-2-[(4R)-2-amino-3,4,5,6-tetrahydro-4-pyrimidinyl]glycyl-(2S)-2-[[(3R,4R)-3,6-diamino-4-hydroxy-1-oxohexyl]amino]-b-alanyl-L-seryl-L-seryl]
Title: Enviomycin
CAS Registry Number: 33103-22-9
CAS Name: Tuberactinomycin N
Synonyms: (R)-1-[(3R,4R)-4-hydroxy-3,6-diaminohexanoic acid]-6-[L-2-(2-amino-1,4,5,6-tetrahydro-4-pyrimidinyl)glycine]viomycin
Molecular Formula: C25H43N13O10
Molecular Weight: 685.69
Percent Composition: C 43.79%, H 6.32%, N 26.56%, O 23.33%
Literature References: Polypeptide antibiotic produced by a mutant of Streptomyces griseoverticillatus var. tuberacticus. Isoln and characterization: T. Ando et al., J. Antibiot. 24, 680 (1971); A. Nagata et al., in Advan. Antimicrob. Antineopl. Chemother. vol. 1/2, M. Hejzlar et al., Eds. (University Park Press, Baltimore, 1972) pp 1039-1041. Prepn: J. Abe et al., DE 2133181; eidem, US 3892732 (1972, 1975 both to Toyo Brewing Co., Ltd.). Structural studies: H. Yoshioka et al., Tetrahedron Lett. 1971, 2043; T. Wakamiya, T. Shiba, J. Antibiot. 28, 292 (1975). Pharmacology: H. Hamakawa et al., Oyo Yakuri 8, 817 (1974), C.A. 82, 51530y (1975). Metabolism: T. Shimizu et al., Jpn. J. Antibiot. 27, 279 (1974). Total synthesis: T. Shiba et al., J. Antibiot. 32, 1078 (1979).
 
Derivative Type: Hydrochloride
Molecular Formula: C25H43N13O10.3HCl
Molecular Weight: 795.07
Percent Composition: C 37.77%, H 5.83%, N 22.90%, O 20.12%, Cl 13.38%
Properties: White crystalline powder, mp >245° (dec). [a]D21 -19.1°. uv max (water, 0.1N HCl): 268 nm (E1%1cm 342); uv max (0.1N NaOH): 288 nm (E1%1cm 215). Very sol in water, slightly sol in methanol, ethanol. Insol in common organic solvents.
Melting point: mp >245° (dec)
Optical Rotation: [a]D21 -19.1°
Absorption maximum: uv max (water, 0.1N HCl): 268 nm (E1%1cm 342); uv max (0.1N NaOH): 288 nm (E1%1cm 215)
 
Derivative Type: Sulfate
Trademarks: Tuberactin (Toyo Jozo)
Molecular Formula: C50H92N26O32S3
Molecular Weight: 1665.62
Percent Composition: C 36.05%, H 5.57%, N 21.86%, O 30.74%, S 5.78%
Properties: White crystalline powder. Sol in water, slightly sol in usual organic solvents. LD50 in mice, rats (mg/kg): 485, 680 i.v. (Hamakawa).
Toxicity data: LD50 in mice, rats (mg/kg): 485, 680 i.v. (Hamakawa)
 
Therap-Cat: Antibacterial (tuberculostatic).
Keywords: Antibacterial (Antibiotics); Polypeptides; Antibacterial (Tuberculostatic).