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CAS No 33005-95-7 , 2-(5-benzoylthiophen-2-yl)propanoic acid

  • Name: 2-(5-benzoylthiophen-2-yl)propanoic acid
  • Synonyms: Surgam SR; Acido tiaprofenico; Novo-Tiaprofenic; 33005-95-7; Nu-Tiaprofenic;2-(5-benzoylthiophen-2-yl)propanoic acid; PMS-Tiaprofenic; Dom-tiaprofenic;Tiaprofensaeure; Surgam;
  • CAS Registry Number:
  • Flash Point: 226.1ºC
  • Boiling Point: 450.3ºC at 760 mmHg
  • Density: 1.29 g/cm3
  • Refractive index: 1.612
  • Safety Statements: Poison by ingestion, subcutaneous, and intraperitoneal routes. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of SOx.
  • Flash Point: 226.1ºC
  • EINECS: 251-329-3
  • Molecular Weight: 260.30828
  • InchiKey: GUHPRPJDBZHYCJ-UHFFFAOYSA-N
  • InChI: InChI=1S/C14H12O3S/c1-9(14(16)17)11-7-8-12(18-11)13(15)10-5-3-2-4-6-10/
    h2-9H,1H3,(H,16,17)
  • Molecular Formula: C14H12O3S
  • Molecular Structure:CAS No:33005-95-7 2-(5-benzoylthiophen-2-yl)propanoic acid

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References of 2-(5-benzoylthiophen-2-yl)propanoic acid
Title: Tiaprofenic Acid
CAS Registry Number: 33005-95-7
CAS Name: 5-Benzoyl-a-methyl-2-thiopheneacetic acid
Synonyms: a-methyl-5-benzoyl-2-thienylacetic acid
Manufacturers' Codes: FC-3001; RU-15060
Trademarks: Suralgan (Poli); Surgam (HMR)
Molecular Formula: C14H12O3S
Molecular Weight: 260.31
Percent Composition: C 64.60%, H 4.65%, O 18.44%, S 12.32%
Literature References: Non-steroidal anti-inflammatory. Prepn: F. Clémence, O. Le Martret, DE 2055264 and FR 2112111 (1971 and 1972 to Roussel-UCLAF), C.A. 75, 63597u (1971) and 78, 97473c (1973); F. Clémence et al., Eur. J. Med. Chem. - Chim. Ther. 9, 390 (1974). Pharmacology: eidem, ibid.; H. Fujimura et al., Oyo Yakuri 9, 715 (1975), C.A. 83, 188321w (1975). Review of pharmacology and efficacy in rheumatic diseases and pain control: E. M. Sorkin, R. N. Brogden, Drugs 29, 208-235 (1985).
Properties: mp 96° (isopropyl ether).
Melting point: mp 96° (isopropyl ether)
Therap-Cat: Anti-inflammatory.
Keywords: Anti-inflammatory (Nonsteroidal); Arylpropionic Acid Derivatives.