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CAS No 31793-07-4 , 2-[3-chloro-4-(2,5-dihydropyrrol-1-yl)phenyl]propanoic acid

  • Name: 2-[3-chloro-4-(2,5-dihydropyrrol-1-yl)phenyl]propanoic acid
  • Synonyms: 2-[3-chloro-4-(2,5-dihydropyrrol-1-yl)phenyl]propanoic acid; BRN 1686438; Pirprofenum [INN-Latin]; 31793-07-4; Pirprofeno [INN-Spanish]; Pirprofene [INN-French];Rengasil; EINECS 250-805-8; SU-21524;
  • CAS Registry Number:
  • Flash Point: 202.2°C
  • Boiling Point: 410.8°Cat760mmHg
  • Density: 1.298g/cm3
  • Refractive index: 1.604
  • Safety Statements: Poison by ingestion and intravenous routes. When heated to decomposition it emits toxic fumes of Cl− and NOx.
  • Flash Point: 202.2°C
  • EINECS: 250-805-8
  • Molecular Weight: 251.70876
  • InchiKey: PIDSZXPFGCURGN-UHFFFAOYSA-N
  • InChI: InChI=1S/C13H14ClNO2/c1-9(13(16)17)10-4-5-12(11(14)8-10)15-6-2-3-7-15/
    h2-5,8-9H,6-7H2,1H3,(H,16,17)
  • Molecular Formula: C13H14ClNO2
  • Molecular Structure:CAS No:31793-07-4 2-[3-chloro-4-(2,5-dihydropyrrol-1-yl)phenyl]propanoic acid

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31793-07-4 Pirprofen

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References of 2-[3-chloro-4-(2,5-dihydropyrrol-1-yl)phenyl]propanoic acid
Title: Pirprofen
CAS Registry Number: 31793-07-4
CAS Name: 3-Chloro-4-(2,5-dihydro-1H-pyrrol-1-yl)-a-methylbenzeneacetic acid
Synonyms: 3-chloro-4-(3-pyrrolin-1-yl)hydratropic acid
Manufacturers' Codes: Su-21524
Trademarks: Rangasil (Novartis); Rengasil (Novartis); Seflenyl (Novartis)
Molecular Formula: C13H14ClNO2
Molecular Weight: 251.71
Percent Composition: C 62.03%, H 5.61%, Cl 14.08%, N 5.56%, O 12.71%
Literature References: Non-steroidal anti-inflammatory. Prepn: R. W. Carney, G. DeStevens, US 3641040 (1972 to Ciba); R. W. Carney et al., Experientia 29, 938 (1973). Metabolism: R. C. Luders et al., Clin. Pharmacol. Ther. 21, 721 (1977). Pharmacology: G. Wilhelmi, Pharmacology 16, 268 (1978). Pharmacokinetics: M. Beth et al., J. Clin. Pharmacol. 15, 563 (1975). Comparative efficacy: R. J. Saykaly et al., ibid. 19, 59 (1979). Review of pharmacology and therapeutic efficacy: P. A. Todd, R. Beresford, Drugs 32, 509-537 (1986).
Properties: Crystals from benzene-hexane, mp 98-100°.
Melting point: mp 98-100°
Therap-Cat: Anti-inflammatory.
Keywords: Anti-inflammatory (Nonsteroidal); Arylpropionic Acid Derivatives.
 
 
Status: This monograph has been retired and is no longer subject to revision or update.