Home > Name List By n > N, N-dimethyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine-2- sulfonamide

CAS No 316-81-4 , N,
N-dimethyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine-2-
sulfonamide

  • Name: N,
    N-dimethyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine-2-
    sulfonamide
  • Synonyms: Cephalmin;N,
    N-dimethyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine-2-
    sulfonamide; Mazeptyl; Thioproperazin; Sulfenazin; Majeptyl;Thioperazine; Megeptil; Thioproperazinum [INN-Latin]; Vontil;
  • CAS Registry Number:
  • Melting Point: 140ºC
  • Flash Point: 324°C
  • Boiling Point: 612.2°Cat760mmHg
  • Density: 1.237g/cm3
  • Refractive index: 1.615
  • Safety Statements: Moderately toxic by ingestion. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of SOx and NOx.
  • Flash Point: 324°C
  • EINECS: 206-262-4
  • Molecular Weight: 446.6292
  • InchiKey: VZYCZNZBPPHOFY-UHFFFAOYSA-N
  • InChI: InChI=1S/C22H30N4O2S2/c1-23(2)30(27,
    28)18-9-10-22-20(17-18)26(19-7-4-5-8-21(19)29-22)12-6-11-25-15-13-24(3)
    14-16-25/h4-5,7-10,17H,6,11-16H2,1-3H3
  • Molecular Formula: C22H30N4O2S2
  • Molecular Structure:CAS No:316-81-4 N,<br />N-dimethyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine-2-<br />sulfonamide

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References of N,
N-dimethyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine-2-
sulfonamide
Title: Thioproperazine
CAS Registry Number: 316-81-4
CAS Name: N,N-Dimethyl-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine-2-sulfonamide
Synonyms: 3-dimethylsulfamoyl-10-[3-(4-methylpiperazino)propyl]phenothiazine; 2-dimethylsulfamoyl-10-[3￠-(4￠￠-piperazino)propyl]phenothiazine; thioperazine
Manufacturers' Codes: RP-7843; SKF-5883
Molecular Formula: C22H30N4O2S2
Molecular Weight: 446.63
Percent Composition: C 59.16%, H 6.77%, N 12.54%, O 7.16%, S 14.36%
Literature References: Prepn: GB 814512 (1959 to Rh?ne-Poulenc).
Properties: Crystals, mp 140°.
Melting point: mp 140°
 
Derivative Type: Fumarate
Molecular Formula: C22H30N4O2S2.C4H4O4
Molecular Weight: 562.70
Percent Composition: C 55.50%, H 6.09%, N 9.96%, O 17.06%, S 11.40%
Properties: Crystals, mp 182°.
Melting point: mp 182°
 
Derivative Type: Dimethanesulfonate
CAS Registry Number: 2347-80-0
Synonyms: Thioproperazine mesylate
Trademarks: Majeptil (RPR); Vontil (SKB)
Molecular Formula: C22H30N4O2S2.2CH3SO3H
Molecular Weight: 638.84
Percent Composition: C 45.12%, H 6.00%, N 8.77%, O 20.04%, S 20.08%
 
Therap-Cat: Antipsychotic; antiemetic.
Keywords: Antiemetic; Antipsychotic; Phenothiazines.