Title: Opipramol
CAS Registry Number: 315-72-0
CAS Name: 4-[3-(5
H-Dibenz[
b,f]azepin-5-yl)propyl]-1-piperazineethanol
Synonyms: 5-[g-[4-(b-hydroxyethyl)piperazino]propyl]dibenzo[
b,f]azepine;
N-[3-[4-(2-hydroxyethyl)piperazino]propyl]iminostilbene; 4-[3-(5
H-dibenzo[
b,f]azepin-5-yl)propyl]-1-(2-hydroxyethyl)piperazine
Molecular Formula: C23H29N3O
Molecular Weight: 363.50
Percent Composition: C 76.00%, H 8.04%, N 11.56%, O 4.40%
Literature References: Prepn:
FR M209 (1961 to Rh?ne-Poulenc),
C.A. 58, 3442f (1963); Schindler,
DE 1133729;
CH 359143;
CH 360061 (all 1962 to Geigy),
C.A. 58, 10219a, 10218f, 10218h (1963).
Properties: Crystals, mp 100-101°.
Melting point: mp 100-101°
Derivative Type: Dihydrochloride
CAS Registry Number: 909-39-7
Trademarks: Dinsidon (Novartis); Ensidon (Novartis); Insidon (Novartis)
Molecular Formula: C23H29N3O.2HCl
Molecular Weight: 436.42
Percent Composition: C 63.30%, H 7.16%, N 9.63%, O 3.67%, Cl 16.25%
Properties: Crystals from ethanol, mp 210° (
FR M209); mp 228-230° (
DE 1133729). Sol in water, alcohol; sparingly sol in acetone.
Melting point: mp 210° (
FR M209); mp 228-230° (
DE 1133729)
Therap-Cat: Antidepressant; antipsychotic.
Keywords: Antidepressant; Tricyclics; Antipsychotic; Other Tricyclics.