Title: Agmatine
CAS Registry Number: 306-60-5
CAS Name: 4-(Aminobutyl)guanidine
Synonyms: 1-amino-4-guanidobutane
Molecular Formula: C5H14N4
Molecular Weight: 130.19
Percent Composition: C 46.13%, H 10.84%, N 43.03%
Literature References: Decarboxylated arginine. Found in pollen of
Ambrosia artemisifolia L.,
Compositae, in ergot, in sponges, in herring sperm, in octopus muscle: F. W. Heyl,
J. Am. Chem. Soc. 41, 670 (1919); A. Kossel,
Z. Physiol. Chem. 66, 257 (1910); J. L. Irvin, D. W. Wilson,
J. Biol. Chem. 127, 565 (1939). Prepn of salts:
DE 463576 (1928 to Schering-Kahlbaum AG). Synthesis: A. Kossel,
Z. Physiol. Chem. 68, 170 (1910); K. Odo,
J. Chem. Soc. Jpn. 67, 132 (1946); K. Dose,
Ber. 90, 1251 (1957). Use as marker for tumor cells: F. S. Steven
et al., Anticancer Res. 9, 247 (1989); F. S. Steven
et al., J. Enzyme Inhib. 4, 63 (1990).
Derivative Type: Sulfate
CAS Registry Number: 2482-00-0
Molecular Formula: C5H14N4.H2SO4
Molecular Weight: 228.27
Percent Composition: C 26.31%, H 7.06%, N 24.54%, S 14.05%, O 28.04%
Properties: Needles from dil methanol, mp 231°. Fairly sol in water. Nearly insol in alcohol.
Melting point: mp 231°
Derivative Type: Gold chloride
Molecular Formula: C5H14N4.2HCl.2AuCl3
Molecular Weight: 809.76
Percent Composition: C 7.42%, H 1.99%, N 6.92%, Cl 35.03%, Au 48.65%
Properties: Yellow needles from water, dec 223°.
Use: Biochemical probe