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CAS No 304-84-7 , N,N-diethyl-4-hydroxy-3-methoxybenzamide Search by region : Germany

  • Name: N,N-diethyl-4-hydroxy-3-methoxybenzamide
  • Synonyms: Cardiovanil; Etamivan; Analepticon; Simaron; Vandid; Cardiovamil; N,N-Diethylvanillamide;Vanillic acid diethylamide;N,N-diethyl-4-hydroxy-3-methoxybenzamide;
  • CAS Registry Number:
  • Transport: UN 2811 6.1/PG 3
  • Melting Point: 96-97 °C
  • Flash Point: 196.6°C
  • Boiling Point: 401.4°Cat760mmHg
  • Density: 1.115g/cm3
  • Refractive index: 1.536
  • Safety Statements: Poison by ingestion, intravenous, subcutaneous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx.
  • Hazard Symbols: T: Toxic;
  • Flash Point: 196.6°C
  • EINECS: 206-157-3
  • Molecular Weight: 223.26828
  • InchiKey: BQJODPIMMWWMFC-UHFFFAOYSA-N
  • InChI: InChI=1S/C12H17NO3/c1-4-13(5-2)12(15)9-6-7-10(14)11(8-9)16-3/h6-8,14H,
    4-5H2,1-3H3
  • Risk Statements: 25
  • Molecular Formula: C12H17NO3
  • Molecular Structure:CAS No:304-84-7 N,N-diethyl-4-hydroxy-3-methoxybenzamide

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References of N,N-diethyl-4-hydroxy-3-methoxybenzamide
Title: Ethamivan
CAS Registry Number: 304-84-7
CAS Name: N,N-Diethyl-4-hydroxy-3-methoxybenzamide
Synonyms: N,N-diethylvanillamide; vanillic acid diethylamide; vanillic diethylamide
Trademarks: Vandid (3M Pharma); Cardiovanil; Emivan (USV)
Molecular Formula: C12H17NO3
Molecular Weight: 223.27
Percent Composition: C 64.55%, H 7.67%, N 6.27%, O 21.50%
Literature References: Prepd by dissolving vanillic acid O-acyl amide in NaOH and neutralizing with CO2 or acid: Kratzl, Kvasnicka, Monatsh. Chem. 83, 18 (1952); by refluxing a mixture of vanillic acid, P2O5 and powdered glass in xylene and treating with K2CO3: eidem, US 2641612 (1953 to Oesterr. Stickstoffwerke). Toxicity study: Caujolle et al., Compt. Rend. 243, 609 (1956).
Properties: Needles from ligroin, mp 95-95.5°. LD50 i.p. in rats: 28 mg/kg (Caujolle).
Melting point: mp 95-95.5°
Toxicity data: LD50 i.p. in rats: 28 mg/kg (Caujolle)
Therap-Cat: CNS stimulant; respiratory stimulant.
Keywords: CNS Stimulant; Respiratory Stimulant.